Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,252 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04622540Recruiting
Study for living donor liver transplant patients
This study looks at living donor liver transplant care and follows patients for about 3 years to see how they do over time. If you had (or are scheduled for) a living donor liver transplant and can be followed long-term, this trial may be able to collect your outcomes.
SeoulAges 19–79 - NCT04524871RecruitingPhase 1/Phase 2
Immunotherapy combinations for advanced liver cancer
This Phase 1/2 study tests new combinations of immune system medicines in people with advanced liver cancer that cannot be cured by surgery. It looks for safer treatment and signs that the medicines can shrink or control the cancer.
Costa Mesa, CaliforniaAges 18 years+ - NCT04678583Recruiting
Surgery plan for RAS-mutant colon cancer liver metastases
This trial studies an approach to surgically removing liver metastases from colon (or rectal) cancer that has an RAS gene mutation (KRAS or NRAS). If you qualify, you would be evaluated for whether a “complete” (R0) liver operation is planned and technically possible, aiming to improve cancer control by how the liver is cut.
Mannheim, Baden-WurttembergAges 18 years+ - NCT06472973Recruiting
Addiction support after liver transplant
This trial tests a special addiction support program for people who have had a liver transplant because of alcohol-related liver disease. The goal is to help them stay healthy and avoid drinking again.
BesançonAges 18 years+ - NCT03746210Recruiting
Testing a painless scan to study liver spots in cirrhosis
This trial studies “focal liver lesions,” meaning specific spots in the liver, using a non-invasive (no surgery or biopsy) approach. It may help doctors better understand what these spots are in people who have cirrhosis.
BonnAges 18–99 - NCT06743464Recruiting
Rifaximin before liver transplant for better early liver function
This trial tests whether taking the antibiotic rifaximin just before and after a living-donor liver transplant can help prevent early problems with the new liver. It may be an option for adults having this surgery at the study hospital.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT07685353Recruiting
Genes and graft fat after liver transplant study
This study looks at how genetic differences between liver donors and recipients affect fat buildup in the new liver after transplantation. It may help doctors understand why some transplanted livers develop steatosis (fatty liver) after the surgery.
New DelhiAges 18 years+ - NCT06638502RecruitingPhase 1/Phase 2
Testing HRX215 for liver recovery after surgery
This trial tests a drug called HRX215 to see if it is safe and helps the liver recover after surgery to remove colon cancer tumors that have spread to the liver. It is for people who are having either a minor or major liver resection and have a low risk of liver failure.
Baltimore, MarylandAges 18–75 - NCT07480057Recruiting
Bone health changes after liver transplant
This study tracks how liver transplantation affects your bone density and mineral metabolism. It aims to find changes early, which can help prevent fractures later.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT06988852RecruitingPhase 2
Chemo infusion into liver for colorectal cancer spread
This trial tests a strong chemotherapy combination given directly into the liver's blood supply (called HAIC) for people whose colorectal cancer has spread only to the liver and cannot be removed with surgery yet. The goal is to shrink the liver tumors enough so they can be surgically removed.
Wuhan, HubeiAges 18–75 - NCT07268196Recruiting
How a liver transplant affects sexual function
This study looks at how a liver transplant affects a person's sex life and sexual function. It includes married men who either are waiting for a transplant or have already had one with a healthy working liver.
New Delhi, National Capital Territory of DelhiAges 18–60 - NCT06833619Recruiting
A new way to get a liver biopsy using endoscopic ultrasound
This trial tests a new method for taking a small piece of liver tissue using a special ultrasound camera on a thin, flexible tube. It is for adults who need a liver biopsy because their liver function tests are not normal.
SohagAges 18–100 - NCT07450144Recruiting
Chatbot to Help Reduce Alcohol in Fatty Liver Disease
This study tests a chatbot that helps people with fatty liver disease reduce how much they drink. If you drink regularly and are ready to change, this tool could support you.
Hong KongAges 18 years+ - NCT07651748Enrolling by invitationPhase 1/Phase 2
Testing Secretin to Improve Donated Liver Quality
This trial tests whether adding a hormone called secretin to a machine that preserves donated livers outside the body can improve liver quality and transplant outcomes. You may qualify if you're an adult receiving a standard deceased-donor liver transplant that needs special preservation techniques.
Rotterdam, South HollandAges 18 years+ - NCT07317193Recruiting
Genetic causes of adult bile duct disease
This study looks for new genes that might cause abnormal liver test results or specific bile duct diseases in adults, when standard testing hasn't found a clear cause. It also uses healthy blood donors as a comparison group.
Milan, MilanoAges 18–65 - NCT03694691Recruiting
Creating a checklist for keeping donated livers viable
This study looks at a way to predict whether a donated liver will work well after being kept alive outside the body (“machine perfused”). It may help doctors choose the best livers and improve transplant outcomes.
Boston, MassachusettsAges 18–75 - NCT02784119Recruiting
Temporary bypass during liver transplant to help extended-donor livers
This trial studies a temporary surgical bypass during liver transplantation to improve how well the new liver works, especially when the donor liver is “extended criteria.” It may help patients whose transplant plan includes a higher-risk donor liver by testing whether the bypass better protects the graft.
BordeauxAges 18 years+ - NCT06212635Recruiting
Bleeding risk in liver cirrhosis and liver cancer
This trial studies bleeding problems in people with advanced liver cirrhosis or liver cancer. It aims to improve understanding of when blood transfusions or treatments are needed.
Stockholm, HuddingeAges 18 years+ - NCT06890234Enrolling by invitation
Monitoring liver grafts with a tiny probe during transplant
This study uses a tiny probe placed in the new liver during transplant surgery to monitor its health in real time. It may help doctors detect problems early and improve recovery after transplant.
Ljubljana, SloveniaAges 18–65 - NCT07033364Recruiting
Liver function study after radiation treatment for metastases
This trial studies how well the liver works after stereotactic body radiation therapy (SBRT) for cancer that spread to the liver. If you had this specific type of radiation in three large doses, you may help researchers learn more about liver recovery.
AmsterdamAges 18 years+ - NCT06814990Recruiting
Heart and liver study for TIPSS patients
This study uses MRI and echocardiography to check heart function in people with alcohol-related liver cirrhosis who need a TIPSS procedure. It aims to learn more about how the heart works in these patients.
Jena, ThuringiaAges 18–99 - NCT06374875RecruitingPhase 4
Does metabolic surgery reduce liver scarring?
This study tests if weight loss surgery can improve liver fibrosis (scarring) in people with obesity and advanced liver disease. It may help those considering surgery to know if their liver health can get better.
Phoenix, ArizonaAges 18–75 - NCT07737340Recruiting
Metabolic liver disease in new HIV patients
This study looks at liver health in people newly diagnosed with HIV, before they start HIV treatment. It aims to understand early changes in the liver related to metabolism.
Ankara, AnkaraAges 18 years+ - NCT07191886Recruiting
Managing liver disease: what matters to you?
This study asks people with liver disease about their needs and concerns during regular clinic visits. Your answers may help doctors improve care for others.
Indianapolis, IndianaAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,252 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.