Clinical trials
Low Back Pain clinical trials
Below are recruiting low back pain clinical trials, each written for real people, not researchers. We’re tracking 348 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05986292RecruitingPhase 2
Study of new treatments for chronic pain
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
Birmingham, AlabamaAges 18 years+ - NCT05991440Recruiting
Race and income differences in chronic low back pain study
This study looks at how race and income affect chronic low back pain. Researchers want to understand differences in pain and daily function between Black and White adults with long-lasting back pain.
St Louis, MissouriAges 18–85 - NCT06106191Recruiting
Mindfulness program for chronic low back pain
This trial tests a mindfulness-based program designed to help people with long-term low back pain. It aims to see if combining mindfulness with a personalized approach can improve pain management and daily functioning.
Boston, MassachusettsAges 18 years+ - NCT06153199Recruiting
Managing low back pain in nursery and landscape workers
This study tests a self-management program to help people who work in nurseries or landscaping manage their low back pain. It aims to give you practical tools to reduce pain and stay active at work.
Gainesville, FloridaAges 18 years+ - NCT06208514Recruiting
Brief Pain Exposure Therapy for chronic pain conditions
This study tests a type of talk therapy called Brief Pain Exposure Therapy (BPET) for people with certain chronic pain conditions like fibromyalgia, lupus, or chronic low back pain. It aims to help reduce pain by changing how your brain responds to it.
Ann Arbor, MichiganAges 18 years+ - NCT06271447Recruiting
Pain questionnaire study for chronic low back pain
This study looks at how well pain questionnaires measure changes in chronic low back pain over time. If you have had long-term low back pain, researchers want to see if these surveys can accurately detect meaningful improvements.
Istanbul, None SelectedAges 18–65 - NCT06310096Recruiting
Stretching for chronic low back pain
This study tests whether a special stretching technique for the connective tissue in your lower back can help reduce pain and improve function in people with chronic low back pain (pain lasting 3 months or more). You would attend physiotherapy sessions and do regular stretches.
AnkaraAges 20–60 - NCT06361485RecruitingPhase 1
Umbilical cord injection for chronic low back pain
This study tests whether a special injection made from umbilical cord tissue is safe and can help with long-term low back pain. It is for adults who have not had recent back procedures or certain health problems.
Scottsdale, ArizonaAges 20 years+ - NCT06419439RecruitingPhase 2
Ketamine for Veterans with Chronic Back Pain and Depression
This study tests whether ketamine, combined with talk therapy, can help veterans with both chronic low back pain and depression. The goal is to reduce pain and improve mood.
Ann Arbor, MichiganAges 18 years+ - NCT06446596Recruiting
Phone-based exercise coach vs. standard home exercises for low back pain
This study compares doing exercises at home with a video coach on your phone versus doing standard exercises you get from a doctor. The goal is to see if the video program helps people with low back pain more than regular home exercises.
Valencia, Select OneAges 18–65 - NCT06452030Recruiting
Testing a new exercise for trunk muscles in low back pain
This study is testing a special training program for the muscles that support your spine. It is for people who have had frequent but mild episodes of low back pain that have recently calmed down. The goal is to see if changing how these muscles work can prevent future pain.
GhentAges 18–65 - NCT06454669RecruitingPhase 2
Dronabinol added to opioids for chronic low back pain
This trial tests whether adding dronabinol (a prescription medication derived from cannabis) to your current opioid pain treatment can help reduce chronic low back pain more effectively. It is for people who have had persistent low back pain for at least 3 months and are already on a stable opioid regimen.
Houston, TexasAges 18–64 - NCT07693998Enrolling by invitation
Pain education class for fibromyalgia or chronic back pain
This trial tests a class to help people with fibromyalgia or chronic low back pain learn about their pain and how to manage it. It might help you feel better and understand your pain.
Valencia, ValenciaAges 18 years+ - NCT06537219Recruiting
Fascia stiffness and pain in young adults with chronic back pain
This study looks at how stiffness in the connective tissue (fascia) of the lower back relates to pain in young people with chronic low back pain. It may help find new ways to treat this common problem.
AnkaraAges 18–50 - NCT06544525Recruiting
Pain test to predict physical therapy results for back pain
This trial tests whether a simple pain test can predict how much you will improve with physical therapy for chronic low back pain. It looks at how your body naturally handles pain, which may help tailor your treatment.
Fort Sam Houston, TexasAges 18–64 - NCT06549660Recruiting
Light therapy for chronic low back pain relief
This study tests if a special light treatment (photobiomodulation) can temporarily ease chronic low back pain that comes and goes. It's for people who have had this pain for at least 3 months and speak Portuguese.
São PauloAges 18–65 - NCT06566144Recruiting
Adding osteopathy to standard care for chronic low back pain
This study tests whether adding osteopathy (a type of hands-on therapy) to standard care helps people with long-term low back pain feel better and move more easily. It is for adults with chronic, nonspecific back pain that has lasted at least 6 weeks.
São PauloAges 18–70 - NCT06584721Recruiting
Foot exercises and taping for low back pain with flat feet
This study tests whether simple foot exercises combined with special tape on the foot can reduce low back pain in people whose feet roll inward too much (a condition called hyper-pronation). It may help if you have had back pain for months and also have flat feet.
Wāh, Punjab ProvinceAges 25–45 - NCT06590116Recruiting
Spinal manipulation for chronic low back pain
This study looks at how people feel about spinal manipulation therapy for long-term low back pain. It's for adults who have had pain in their lower back for more than three months and want to share their views on this type of treatment.
Gainesville, FloridaAges 18–70 - NCT06594796Recruiting
Lifestyle program for back pain and weight
This trial tests a combined exercise and lifestyle program for people with long-lasting low back pain who are overweight or have obesity. The program is delivered by physical therapists and aims to improve physical function and reduce pain.
AmsterdamAges 18 years+ - NCT07690449Recruiting
CT signs of nerve irritation in sciatica
This study looks at three specific signs on a CT scan that may show nerve-root irritation in people with sciatica. It only includes patients who are already scheduled for a CT-guided nerve injection to treat their pain.
Nice, Alpes MaritimesAges 18 years+ - NCT06611397Recruiting
Discogen study for lower back pain with leg pain
This trial tests a treatment called Discogen for people with lower back pain that also causes leg pain. It aims to see if the treatment helps reduce pain and improve function.
New York, New YorkAges 21–75 - NCT06656156Recruiting
Stretching technique for chronic low back pain relief
This trial tests a physical therapy stretching method called PNF on the hip and hamstring muscles to see if it reduces chronic low back pain. It may help if you have had non-specific low back pain for over 3 months with tightness in your hips or legs.
Karachi, SindhAges 15–40 - NCT06671132RecruitingPhase 2
Computer training for pain relief using smell exercises
This trial tests a computer program that uses smell training to help people with chronic low back pain. It aims to reduce pain by retraining brain connections.
Washington D.C., District of ColumbiaAges 18–85
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Common questions
- Are there clinical trials for low back pain?
- Yes. Clin2 currently lists 348 recruiting low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.