Clinical trials
Lung cancer clinical trials
Cancer that begins in the lungs, often linked to smoking but also affecting non-smokers. We’re tracking 2,028 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06917573RecruitingPhase 2
Cemiplimab for advanced lung cancer with high PD-L1
This trial tests a drug called cemiplimab (an immunotherapy) for people with advanced lung cancer that has high PD-L1 levels. It uses a simple blood test to track how well the treatment is working.
Alicante, AlicanteAges 18 years+ - NCT06918132RecruitingPhase 2
Cemiplimab and Fianlimab before lung cancer surgery
This trial tests whether two immunotherapy drugs (cemiplimab and fianlimab) given before surgery can help treat stage IB to IIIB non-small cell lung cancer. You must have a PD-L1 level of at least 1% and your surgeon must think the tumor can be fully removed.
Rochester, MinnesotaAges 18 years+ - NCT06926075RecruitingPhase 1/Phase 2
Early trial of KESONOTIDE™ for solid tumors
This trial tests a new tablet called KESONOTIDE™ for people with solid tumors that have spread. The goal is to see if it can help when other treatments have stopped working or are not an option.
Kogarah, New South WalesAges 18 years+ - NCT06926140Recruiting
Acupuncture with immunotherapy for advanced lung cancer
This trial tests if adding acupuncture to standard immunotherapy and chemotherapy helps people with advanced lung cancer. It is for those who have not had treatment before and whose tumors have low PD-L1 levels.
Hefei, AnhuiAges 18–75 - NCT06926179Recruiting
Immunotherapy before surgery or radiation for lung cancer
This trial tests using immunotherapy before surgery or radiation for non-small cell lung cancer. It looks at how safe and effective this approach is and how it affects survival.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06963307Recruiting
Blood test for early lung cancer detection
This study is testing a new blood test that looks for changes in DNA to detect lung cancer early. It's for people with a new lung cancer diagnosis, those with uncertain CT scan results, healthy volunteers, or those with chronic lung problems.
Ramat GanAges 18 years+ - NCT06975384Recruiting
Sleep and lung cancer treatment outcome study
This study looks at how sleep disturbances affect how well lung cancer treatments work. It may help doctors understand if improving sleep can lead to better treatment results.
Changsha, HunanAges 18 years+ - NCT07001670Recruiting
Tele-yoga for recovery after lung cancer surgery
This trial tests whether online yoga classes can help people with lung cancer recover better after surgery to remove part of a lung. If you have had surgery for early-stage lung cancer and can use the internet, you may be able to join.
IstanbulAges 18–65 - NCT07005128RecruitingPhase 3
New Drug Combo for First-Line Extensive Small Cell Lung Cancer
This trial tests adding a new immunotherapy drug (tarlatamab) to the standard first-line chemo-immunotherapy for extensive-stage small cell lung cancer. It aims to see if the combination works better than the usual treatment alone.
Casa Grande, ArizonaAges 18–99 - NCT07008664Recruiting
DNA test for lung cancer diagnosis
This study is testing a new blood test to help diagnose lung cancer by looking at certain markers in your DNA. Researchers want to see if this test can accurately find lung cancer, which could lead to earlier detection.
Glen Burnie, MarylandAges 18 years+ - NCT07008742Recruiting
Blood and tissue collection study for certain lung cancers
This study collects blood and tissue samples from people with non-small cell lung cancer (NSCLC) either before or after treatment. It aims to help researchers learn more about how tumors respond, especially in cancers with specific genetic changes or after certain pre-surgery therapies.
London, United KingdomAges 18 years+ - NCT07012031RecruitingPhase 1/Phase 2
Sotorasib and trastuzumab deruxtecan for KRAS G12C lung cancer
This trial tests a combination of two drugs, sotorasib and trastuzumab deruxtecan, for people with advanced or metastatic non-small cell lung cancer that has a KRAS G12C mutation. It may be an option if you've already had treatment with a KRAS G12C inhibitor, immunotherapy, and chemotherapy.
Sacramento, CaliforniaAges 18 years+ - NCT07024433Recruiting
No-breathing-tube surgery for early lung cancer
This study tests a special 'tubeless' anesthesia technique — avoiding breathing tubes during surgery — for people with early-stage lung cancer. The goal is to see if it reduces lung problems after the operation.
Fuzhou, FujianAges 18–70 - NCT07026110Recruiting
PET/CT for distinguishing non-small cell lung cancer
This study uses a special PET/CT scan to better tell if a lung nodule is non-small cell lung cancer. If you have a solid nodule in your lung that's at least 8 mm and might be cancer, this scan could help get a clearer diagnosis.
ShanghaiAges 18–80 - NCT07026669Recruiting
Studying treatment response in small cell lung cancer with genetic testing
This trial collects blood and tumor samples from people newly diagnosed with small cell lung cancer to study how genetic markers can predict treatment success and monitor disease over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07041320Recruiting
Oral chemo and immunotherapy for older adults with lung cancer
This trial is testing a combination of an oral chemotherapy pill (vinorelbine) and an immunotherapy drug (PD-1 inhibitor) for people aged 65 and older with advanced non-small cell lung cancer who have not had treatment before. The goal is to see if this approach can help control the cancer with fewer side effects.
Hefei, AnhuiAges 65 years+ - NCT07057102Recruiting
Gene testing to predict lung cancer treatment response and monitor recurrence
This trial uses advanced gene sequencing technology on blood and tumor tissue samples from people with non-small cell lung cancer. The goal is to see if this testing can help doctors better predict which treatments will work and detect if the cancer comes back early.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07061535RecruitingPhase 2
Sintilimab, tafolecimab and chemo for advanced small cell lung cancer
This trial tests a combination of two immunotherapy drugs (sintilimab and tafolecimab) plus standard chemotherapy as a first treatment for extensive-stage small cell lung cancer. The goal is to see if adding these drugs helps people live longer and have better outcomes.
Changsha, HunanAges 18 years+ - NCT07062172Recruiting
Lung cancer screening for family members
This trial offers a low-dose chest CT scan to screen for lung cancer in family members of people with a specific genetic mutation driving their lung cancer. It aims to catch cancer early in those at higher risk.
Orange, CaliforniaAges 18–80 - NCT07102147Recruiting
Telehealth Therapy for Lung Cancer Patients at Penn Medicine
This trial offers therapy sessions (via phone or video) for people with lung cancer who are dealing with depression, anxiety, or other emotional concerns. It's part of Penn Medicine's collaborative care program and aims to make mental health support easier to access while you are being treated for lung cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07103395RecruitingPhase 2
Study of chemo, radiation, and dual immunotherapy for stage 3 lung cancer
This trial tests combining chemotherapy, radiation therapy, and two immune-boosting drugs (iparomlimab and tuvonralimab) as a first treatment for locally advanced non-small cell lung cancer that cannot be surgically removed. It aims to see if this combination improves outcomes compared to standard care.
Guangzhou, GuangdongAges 18–75 - NCT07104630RecruitingPhase 2
Pulmonary rehab for advanced lung cancer
This study tests a pulmonary rehabilitation program—special exercises and breathing training—to help people with advanced lung cancer feel less short of breath and improve their daily function and quality of life.
Cleveland, OhioAges 18 years+ - NCT07153055RecruitingPhase 1/Phase 2
Lurbinectedin with osimertinib for transformed small cell lung cancer
This trial tests a combination of two drugs—lurbinectedin and osimertinib—for people whose lung cancer started as EGFR-mutated non-small cell lung cancer but has changed into small cell lung cancer. The goal is to see if this combination can help control the cancer.
Indianapolis, IndianaAges 18 years+ - NCT07153445RecruitingPhase 2
Atezolizumab before and after surgery for stage III lung cancer
This trial tests whether the immunotherapy drug atezolizumab, given before and after surgery, can help treat stage III non-small cell lung cancer that has not spread to other parts of the body. It is for people who have not had any previous cancer treatment for this disease.
Alicante, AlicanteAges 18 years+
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Common questions
- Are there clinical trials for lung cancer?
- Yes. Clin2 currently lists 2,028 recruiting lung cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.