Clinical trials
Lupus or SLE clinical trials
Below are recruiting lupus or sle clinical trials, each written for real people, not researchers. We’re tracking 343 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06842316Recruiting
Study on cannabis-like compounds for inflammatory arthritis
This trial tests whether plant-based compounds similar to cannabis (called phytocannabinoids) can help calm inflammation and improve immune function in people with certain types of arthritis or autoimmune diseases like lupus or Sjögren's disease. It aims to offer a new way to treat these conditions without the 'high' of marijuana.
OrléansAges 18 years+ - NCT06880653Recruiting
Exercise dose study for arthritis pain
This study looks at how different amounts of exercise affect arthritis symptoms. If you have arthritis or a related condition, you may be asked to try a specific weekly exercise goal to see if it helps your pain and mobility.
Columbia, South CarolinaAges 18 years+ - NCT06934447RecruitingPhase 1
CAR-T cell therapy for hard-to-treat lupus in kids
This trial tests a new type of cell therapy, called BCMA/CD70 CAR-T, for children with lupus that hasn't improved with standard treatments. The goal is to see if it can safely reduce disease activity.
Hangzhou, ZhejiangAges 5 years+ - NCT07000110Recruiting
Anifrolumab and risk study for lupus patients
This study looks at potential risks of the lupus medication anifrolumab in people with moderate to severe SLE. It focuses on serious infections and malignancies to see how safe the treatment is.
CopenhagenAges 18–130 - NCT07000916Recruiting
Follow-up study for new arthritis in kids and young adults
This study follows children and young adults newly diagnosed with certain types of arthritis or related conditions to learn more about their health over time. It may help doctors better understand how these diseases progress and how treatments work.
BrusselsAges 2–50 - NCT07038382RecruitingPhase 2
Study of HLX79 with Rituximab for Active Kidney Disease
This trial tests a new drug called HLX79 (a human sialidase fusion protein) combined with rituximab, compared to a placebo, for people with active membranous nephropathy (a kidney disease). It aims to see if this combination can reduce protein in the urine and improve kidney function.
BeijingAges 18–75 - NCT07049653Recruiting
Anifrolumab pregnancy safety study
This study looks at pregnancy outcomes in women with lupus (SLE) who were or were not treated with the drug anifrolumab. It helps understand if anifrolumab is safe to use during pregnancy.
Cary, North CarolinaAges 18–130 - NCT07053891Recruiting
Safety survey of LUPKYNIS for lupus nephritis
This study is a safety survey for people who are just starting to take LUPKYNIS for lupus nephritis, a type of kidney inflammation caused by lupus. It aims to collect information on how well the drug works and any side effects in real-world use.
Osaka, OsakaAges 15 years+ - NCT07072611RecruitingEarly Phase 1
Safety study of SOF-SKN cream in healthy volunteers
This study tests a cream called SOF-SKN on healthy people to see if it's safe and how the body handles it. It is a first-in-human trial, so if you join, you'll help researchers learn about the cream before testing it in patients.
Melbourne, VictoriaAges 18–64 - NCT07077304Recruiting
Cardiac imaging study for inflammatory heart diseases
This study uses heart scans (MRI or nuclear imaging) to better understand inflammatory heart conditions. If you have a suspected inflammatory heart disease and are already scheduled for one of these scans, you may be able to join.
ParisAges 18 years+ - NCT07086989Recruiting
Heart health study for kids with chronic conditions
This study looks at heart disease risk in children and young adults (ages 6-25) with long-term health conditions like certain heart, kidney, or diabetes disorders. The goal is to better understand and manage heart risks early.
BudapestAges 6–25 - NCT07128966Recruiting
Collect biospecimens and health data for research
This study collects blood, saliva, or other biospecimens and health information from people with certain medical conditions. Your samples and data will help researchers better understand diseases and develop new treatments.
Lexington, MassachusettsAges 18–90 - NCT07246096RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new CAR-T cell treatment for people with certain autoimmune diseases that have not responded to standard therapies. The treatment uses your own immune cells modified to target and attack disease-causing cells.
ShanghaiAges 18–70 - NCT07249060Recruiting
Interferon levels in cancer and autoimmune disease patients
This study looks at a protein called interferon in the blood of people with cancer who are starting immunotherapy, and people with certain autoimmune diseases (such as lupus, Sjögren's syndrome, scleroderma, or inflammatory myopathy). The goal is to compare interferon patterns and better understand immune responses.
Pamplona, NavarreAges 18 years+ - NCT06527872Recruiting
Study of belimumab for lupus kidney disease in real life
This study looks at how well belimumab (Benlysta) works in real-world settings for adults with lupus nephritis (kidney inflammation caused by lupus). If you started belimumab in the past 6–24 months, the researchers will review your medical records to see how your kidney health has changed.
Baltimore, MarylandAges 18 years+ - NCT07339540RecruitingEarly Phase 1
BCMA gene therapy for recurring autoimmune diseases
This early-phase trial tests a new gene therapy (BCMA LV injection) for people with autoimmune diseases like lupus, IgG4-related disease, scleroderma, myositis, or vasculitis that keep coming back or don't respond to standard treatments. The goal is to see if targeting a specific immune cell protein (BCMA) can help control the disease.
Wuhan, HubeiAges 18–65 - NCT07350395Recruiting
How steroids affect children with autoimmune conditions
This study talks to children and young people with autoimmune or inflammatory conditions (like juvenile arthritis) who have taken steroids in the past two years. It aims to understand how steroids impact their daily lives and feelings.
Bristol, North SomersetAges Up to 18 years - NCT07352332Recruiting
Immune study of a new treatment for hard-to-treat lupus in children
This study looks at how a treatment called CD3xCD19 BiTE affects the immune system of children with lupus that hasn't gotten better with standard medicines. It uses leftover blood samples to learn more about why some children don't respond to usual treatments.
HangzhouAges 5 years+ - NCT07361094RecruitingPhase 1
CAR-T therapy for autoimmune disease after prior treatment
This trial tests a new CAR-T cell therapy that targets two proteins (CD19 and BCMA) on immune cells. It is for people with certain autoimmune diseases (like lupus or scleroderma) that have not responded well to standard treatments or have relapsed after prior cell therapy.
BeijingAges 18–70 - NCT07363460RecruitingPhase 2
HSK39297 tablets for active lupus nephritis
This study tests a new drug called HSK39297 combined with standard treatments (steroids and mycophenolate mofetil) for people with active lupus nephritis. It aims to see if the combination is safe and effective in reducing kidney inflammation.
Nanjing, JiangsuAges 18–75 - NCT07371468RecruitingPhase 1
Study of an experimental drug for lupus, rheumatoid arthritis, and related conditions
This trial tests a new drug called GSK5926371 for people with certain autoimmune diseases that affect the joints, skin, and other tissues. It aims to see if the drug is safe and how well it works.
Buenos AiresAges 18–70 - NCT01802034Recruiting
Study kidney samples to understand autoimmune, inflammatory, and diabetic disease
This trial collects and studies kidney tissue samples to better understand what drives kidney problems linked to autoimmune, inflammation, and diabetes. Your participation may help researchers develop better ways to diagnose and treat these conditions.
New York, New YorkAges 18 years+ - NCT07515638Recruiting
Immune System Study for Autoimmune Diseases
This research study collects samples and information from people with rheumatoid arthritis, lupus, or scleroderma, plus healthy volunteers, to better understand how the immune system works in these conditions. By comparing these groups, researchers hope to find new ways to treat and manage autoimmune diseases.
MontpellierAges 18 years+ - NCT02422875Enrolling by invitation
Study of immune markers in autoimmune disease and lupus
This study looks at blood and immune cell markers (autoantibodies and immune cell “signatures”) to better understand autoimmune conditions, including lupus. It may help researchers identify which markers are linked to disease and how immune cells respond after vaccination.
Atlanta, GeorgiaAges 18 years+
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Common questions
- Are there clinical trials for lupus or sle?
- Yes. Clin2 currently lists 343 recruiting lupus or sle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lupus or sle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lupus or sle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.