Clinical trials
Male Infertility clinical trials
Below are recruiting male infertility clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07337265Recruiting
Royal jelly for unexplained male infertility
This trial tests whether taking royal jelly supplements for 3 months can improve sperm quality and fertility in men with unexplained infertility. It might help if you and your partner have been trying for a baby for over a year without success, and all standard tests are normal.
Istanbul, BaşakşehirAges 18–45 - NCT06324071Recruiting
Study of TetraSOD for male infertility
This trial tests if a supplement called TetraSOD can improve sperm quality in men with infertility of unknown cause. It may help if you and your partner have been trying for at least a year without success.
BarcelonaAges 18–45 - NCT07345455Recruiting
Probiotics for improving sperm quality in male infertility
This trial tests whether taking probiotics can improve sperm quality in men with unexplained infertility. It may help if you have low sperm count, low motility, or abnormal shape.
New Taipei CityAges 20–45 - NCT06880302Recruiting
Male infertility research for sperm and tissue samples
This trial collects sperm, semen, and testicular tissue samples from men undergoing fertility treatments to build a biobank for research. If you are providing such samples for freezing, you can help advance understanding of male infertility.
Basking Ridge, New JerseyAges Any age - NCT06539104Recruiting
Artificial intelligence to improve egg and embryo testing in IVF
This trial uses artificial intelligence to assess the quality of eggs and embryos during IVF. It aims to help doctors select the best embryos for transfer, potentially increasing the chance of a successful pregnancy.
PragueAges 18–49 - NCT07265908Enrolling by invitation
Biobank study for gynecological and fertility conditions
This trial creates a biobank of samples from people with gynecological issues, infertility, or pregnancy problems. It aims to help researchers better understand these conditions and develop future treatments.
Milan, MilanAges Any age - NCT06956287Recruiting
New sperm-wash device for infertility couples
This trial tests a new device that cleans sperm before it's used in intrauterine insemination (IUI), a common fertility treatment. It aims to see if this device improves sperm quality and pregnancy chances for couples struggling with infertility.
Taichung, Taichung CityAges 25–50 - NCT06419127Enrolling by invitation
Embryo time-lapse imaging with genetic testing in IVF
This trial tests whether using a special time-lapse camera to watch embryos develop, together with genetic testing (PGT), can help choose the healthiest embryos for IVF. It may help improve the chances of a successful pregnancy.
Fort Lauderdale, FloridaAges 18–50 - NCT07684339Recruiting
Sperm protein test and fertility treatment
This study looks at a protein in sperm called phospholipase C zeta, which helps eggs develop after fertilization. It aims to see if measuring this protein can predict how well a couple will do with fertility treatments like IVF or ICSI.
Abu DhabiAges Any age - NCT05514223Recruiting
Testing sperm samples to understand lifestyle, gut, and sperm quality
This study measures “free radicals” in sperm to see how lifestyle and the microbiota (gut/community of microbes) may relate to sperm health. You may be asked to provide a semen sample as part of standard fertility testing, unless certain health factors apply.
Groningen, Provincie GroningenAges 18–55 - NCT05479474Recruiting
PRP treatment study for men with testicular infertility
This trial studies whether platelet-rich plasma (PRP) can improve fertility in men with a specific cause of infertility called NOA who have not had success with prior procedures. It may help improve the chance of getting usable sperm for conception.
Stanford, CaliforniaAges 18 years+ - NCT04298255Recruiting
Testicular injection therapy for certain causes of male infertility
This trial studies a special lab procedure where selected immature sperm cells are injected to help infertile couples achieve pregnancy. It is designed for couples where the man has a specific type of sperm-making problem found during a testicular sperm extraction.
Winston-Salem, North CarolinaAges 18 years+ - NCT07669584RecruitingPhase 2/Phase 3
Testing PKB171 for mild male infertility in couples
This study tests a new oral medication (PKB171) compared to a placebo for couples who have mild male infertility and have not tried IVF/ICSI before. The goal is to see if PKB171 can help them conceive naturally.
Pamplona, NavarreAges 18–38 - NCT07546435Recruiting
Male experiences with fertility treatment for low sperm quality
This study explores men's experiences undergoing ICSI, a fertility treatment that helps when sperm quality is reduced. Researchers want to understand how the treatment affects you physically and emotionally.
Skive, Midt JyllandAges 18 years+ - NCT06841861RecruitingPhase 1/Phase 2
Testicular organoid study for male fertility
This trial uses tiny lab-grown testicles to study sperm production. It may help men with infertility learn more about why they can't make sperm.
San Francisco, CaliforniaAges 18–60 - NCT07456397Recruiting
AI to predict sperm success in IVF
This trial tests a new AI system that analyzes sperm to predict how well they might work in fertility treatments like IVF or ICSI. It aims to help doctors choose the best sperm for a successful pregnancy.
Barcelona, BarcelonaAges 18–60 - NCT07481370Enrolling by invitationPhase 2
Comparing Two Medicines for Male Infertility
This study tests two medicines—isotretinoin and human chorionic gonadotropin (hCG)—to see if they can improve sperm production in men with low sperm counts or no sperm due to certain causes. It might help if you haven't responded to other treatments before.
Omaha, NebraskaAges 19–50 - NCT05951075Recruiting
Power prenatal vitamins study for men with specific sperm results
This study looks at whether a specific “power” prenatal vitamin helps improve sperm measures in men whose at-home sperm test results fall in a certain range. It’s mainly for men living in the US or Canada who aren’t taking other prenatal vitamins already and don’t have known causes of male infertility.
Encino, CaliforniaAges 18–50 - NCT06193850Recruiting
Quality of life study for urology outpatients
This study is checking how your daily life is affected by your urology condition. It is an observational study, meaning you will just fill out questionnaires about your quality of life at your regular clinic visits.
Milan, LombardyAges 18 years+ - NCT06384794Recruiting
ZyMōt sperm selection and its effect on embryo chromosome health
This study tests whether a sperm selection method called ZyMōt can help improve the chromosome health (ploidy) of embryos in couples who are already doing ICSI and PGT-A. It focuses on women over 37 and uses a fresh semen sample.
MadridAges 18 years+ - NCT07650955Recruiting
Two surgery approaches for enlarged veins affecting fertility
This trial compares two different surgical techniques to treat bilateral varicocele (enlarged veins in the scrotum) that may be causing infertility. The goal is to see which approach works better and causes fewer complications.
Banī Suwayf, Beni Suweif GovernorateAges 18–45 - NCT07605182Recruiting
Sperm Sorting Device to Improve IVF Success in Older Fathers
This study tests whether a special device that selects the most active sperm can improve IVF success rates when the male partner is 40 or older. The goal is to see if this sorting technique, combined with genetic testing of embryos, leads to healthier pregnancies.
Hà Nội, Ha DongAges 40 years+ - NCT07523022Enrolling by invitationPhase 4
Fertility Treatments for Low Sperm Count or Quality
This study compares two different hormone treatments to see which one better improves sperm health and increases pregnancy chances in men with low or abnormal sperm. You'll receive either injections or pills designed to boost sperm production.
SzegedAges 18 years+ - NCT07375238Recruiting
Gazpacho daily for better sperm health
This study tests whether drinking gazpacho daily can improve sperm quality and reduce stress in the body. It may help men with low or abnormal sperm counts.
Madrid, MadridAges 18–45
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Male Infertility trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for male infertility?
- Yes. Clin2 currently lists 33 recruiting male infertility studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a male infertility trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a male infertility trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.