Clinical trials
Male clinical trials
Below are recruiting male clinical trials, each written for real people, not researchers. We’re tracking 236 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05379556Recruiting
Study for long COVID sexual and reproductive symptoms
This study is looking at people who have recovered from COVID-19 but still have ongoing (long COVID) sexual, reproductive, or related symptoms. Researchers want to learn about these lingering problems and what may help, based on your answers and study procedures.
Naples, ItalyAges 18 years+ - NCT06706921RecruitingPhase 4
Predicting treatment success with PET scans in prostate cancer
This study looks at whether a special PET scan can help predict how well a targeted radiation therapy (LuPSMA) works in men with advanced prostate cancer that has spread. You would get several PET scans before and after treatment to see if the scan results can forecast your outcome.
Los Angeles, CaliforniaAges 18 years+ - NCT05345418RecruitingPhase 1/Phase 2
Cord blood stem cell treatment for low male hormones
This trial tests whether umbilical cord stem cells can improve hormone-related sexual function in men with low testosterone and related symptoms. It’s an early-phase study, so the goal is to see safety and whether symptoms and hormone measures improve.
HanoiAges 50–70 - NCT04098822Recruiting
Survey study for men with a Virtue male sling
This study follows men who have the Virtue male sling to collect longer-term experience through questionnaires and medical data review. It may help improve how this sling is used and understood over time.
AngersAges 18 years+ - NCT05771168Recruiting
Surgery for men with stress urinary leakage
This study looks at men who are having surgery for stress urinary incontinence (urine leakage when coughing, sneezing, or exerting yourself) using devices like a sling or artificial urinary sphincter. It will follow how patients do after surgery using questionnaires, to understand benefits and experiences.
Roma, RomeAges 18 years+ - NCT06468462RecruitingPhase 4
Comparing STI prevention strategies for Kenyan men
This study tests two ways to prevent STIs in men who have sex with men in Kenya: taking antibiotics only when you have symptoms, or taking a single antibiotic pill (doxycycline) shortly after sex. It aims to find which approach works better for keeping you healthy.
KisumuAges 18–29 - NCT07444021Recruiting
Resistance exercise and appetite in healthy young adults
This study looks at how resistance exercise (like weightlifting) affects your body's energy balance and appetite. It's for healthy young adults who want to help scientists understand how exercise impacts hunger and metabolism in men and women.
TaipeiAges 20–30 - NCT07546435Recruiting
Male experiences with fertility treatment for low sperm quality
This study explores men's experiences undergoing ICSI, a fertility treatment that helps when sperm quality is reduced. Researchers want to understand how the treatment affects you physically and emotionally.
Skive, Midt JyllandAges 18 years+ - NCT06339996Recruiting
Male supplement for better sperm quality and aging
This study tests whether a specially designed supplement for men can improve sperm quality and help with age-related fertility issues. It may be an option if your semen analysis shows below-normal results.
Kaohsiung CityAges 30–50 - NCT05501704RecruitingPhase 2
Testosterone-blocking therapy for male breast cancer
This Phase 2 study tests an oral treatment (called “ET”) to treat hormone-receptor–positive, HER2-negative invasive breast cancer in men. It may help shrink or control cancer without using standard cancer treatments first.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07337265Recruiting
Royal jelly for unexplained male infertility
This trial tests whether taking royal jelly supplements for 3 months can improve sperm quality and fertility in men with unexplained infertility. It might help if you and your partner have been trying for a baby for over a year without success, and all standard tests are normal.
Istanbul, BaşakşehirAges 18–45 - NCT06671210Recruiting
Urine HPV testing for men
This study is testing whether a urine test can detect human papillomavirus (HPV) in men. HPV is a common virus that can cause certain cancers. The goal is to see if a simple urine test works as well as other methods. If you are an adult male who has been sexually active, this study may be an option.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07361120RecruitingPhase 2
Plan a vasectomy device study for long-term birth control
This study tests a new device for vasectomy. It's for men who want a long-term birth control option and are in good health, between 25 and 65 years old, with a normal body weight and sperm count.
Maribyrnong, VictoriaAges 25–65 - NCT07076771Recruiting
Testosterone and artery blockage in young men with heart disease
This study looks at whether testosterone levels are linked to how blocked the heart arteries are in young men (under 45) with early heart disease. It involves a one-time blood test during a planned cardiac catheterization.
SohagAges Up to 45 years - NCT04049331RecruitingPhase 2
Testosterone therapy for cancer survivors with fatigue
This trial tests whether testosterone replacement can help male cancer survivors who have ongoing fatigue and low testosterone levels. It is for men who have completed chemotherapy or radiation and are cancer-free for at least a year.
Boston, MassachusettsAges 18–54 - NCT05435222Recruiting
Male-only therapy program for major depression
This study tests a counseling/psychotherapy program designed specifically for men with major depression. If you qualify, you may be offered this structured therapy and followed to see whether it helps depressive symptoms.
Zurich, Canton of ZurichAges 25–50 - NCT05951075Recruiting
Power prenatal vitamins study for men with specific sperm results
This study looks at whether a specific “power” prenatal vitamin helps improve sperm measures in men whose at-home sperm test results fall in a certain range. It’s mainly for men living in the US or Canada who aren’t taking other prenatal vitamins already and don’t have known causes of male infertility.
Encino, CaliforniaAges 18–50 - NCT06190899RecruitingPhase 1/Phase 2
Testing gedatolisib plus darolutamide in advanced prostate cancer
This trial tests a new combination of two drugs, gedatolisib and darolutamide, in men with prostate cancer that has spread and stopped responding to hormone therapy. The goal is to see if the combination can help control the cancer when standard treatments have stopped working.
Detroit, MichiganAges 18 years+ - NCT06266416Recruiting
Black caregivers & girls empowerment study
This study tests a program called IMARA to support black male caregivers and the girls they care for. It aims to improve family relationships and reduce risky behaviors in girls.
Chicago, IllinoisAges 13 years+ - NCT06324071Recruiting
Study of TetraSOD for male infertility
This trial tests if a supplement called TetraSOD can improve sperm quality in men with infertility of unknown cause. It may help if you and your partner have been trying for at least a year without success.
BarcelonaAges 18–45 - NCT06339840Recruiting
Lifestyle change for weight and fertility in obese men
This study tests whether a lifestyle program (diet and exercise) can help men with obesity lose weight and improve their chances of fathering a child through fertility treatment. You and your partner can join if you are an obese male, your partner has a healthy weight and regular periods, and you are both planning treatment at our center.
Zhengzhou, HenanAges 22–40 - NCT05370651Recruiting
Emsella chair versus sham treatment for male ejaculation problems
This trial compares an Emsella chair treatment to a sham (fake) treatment to help men with ejaculation difficulties. It wants to see whether the chair improves symptoms when other options have not helped enough.
Royal Oak, MichiganAges 18 years+ - NCT06542237RecruitingPhase 1/Phase 2
Study of a new male birth control pill for healthy men
This trial tests an experimental birth control pill (YCT-529) taken daily. It aims to see if the drug can safely and effectively prevent pregnancy in healthy men who do not plan to have children in the future.
Grafton, AucklandAges 28–70 - NCT06689085RecruitingPhase 3
Testosterone replacement study for adolescent boys with low testosterone
This trial tests a testosterone injection (XYOSTED) to see if it's safe and effective for replacing testosterone in teenage boys who have low levels due to a known medical condition. It lasts 52 weeks, with an optional 2-year follow-up.
Los Angeles, CaliforniaAges 12–17
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Common questions
- Are there clinical trials for male?
- Yes. Clin2 currently lists 236 recruiting male studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a male trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a male trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.