Clinical trials · Minnesota
Malignant Solid Neoplasm clinical trials in Minnesota
We’re tracking 55 recruiting malignant solid neoplasm studies with a site in Minnesota — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Minnesota
- NCT04585958RecruitingPhase 1
DS-8201a plus olaparib for HER2-positive platinum-resistant ovarian cancer
This trial tests whether combining DS-8201a with olaparib can slow or shrink HER2-positive ovarian cancer that has returned quickly after platinum chemotherapy. It’s a Phase 1 study, meaning it mainly checks safety and finds the best dose, while also looking for signs of anti-cancer activity.
Rochester, MinnesotaAges 18 years+ - NCT06304168Recruiting
Blood, tissue, and urine tests to detect cancer early
This study is testing whether simple blood, tissue, and urine samples can help find cancer earlier and identify where it started. Participating could help improve future cancer detection for everyone.
Rochester, MinnesotaAges 18 years+ - NCT05411523Recruiting
Spinal cord stimulation study for long-term chemotherapy nerve pain
This trial tests whether spinal cord stimulation can reduce pain and improve quality of life in people with long-lasting nerve pain from chemotherapy (CIPN). You must already have tried at least two nerve-pain medicines and still have significant pain, and you must have had a successful spinal cord stimulator test before joining.
Rochester, MinnesotaAges 18 years+ - NCT06410209RecruitingPhase 2
Walking Juntos: Smartphone program to help Hispanic cancer survivors be active
This study will test if a smartphone program and social media group can help Hispanic/Latino teens and young adults who had childhood cancer become more physically active. You would wear a Fitbit and use a phone app with culturally tailored tips and support.
Minneapolis, MinnesotaAges 15–20 - NCT04871542Recruiting
Predicting risk of immune therapy side effects
This study tries to predict who is more likely to get serious side effects from immune checkpoint medicines used for solid tumors. You may help researchers by answering questionnaires before treatment and during follow-up, and by possibly storing sample specimens.
Minneapolis, MinnesotaAges 18 years+ - NCT07477886Recruiting
Using room sensors to spot early warnings for hospitalized cancer patients
This study uses special sensors in patient rooms to monitor movement and other signals that might show early signs of medical problems. The goal is to see if these sensors can help doctors and nurses step in sooner for cancer patients in the hospital.
Rochester, MinnesotaAges 18 years+ - NCT06620302RecruitingPhase 1/Phase 2
Adding DT2216 to chemo for relapsed solid tumors and FLC
This trial is testing whether adding a new drug, DT2216, to standard chemotherapy can help treat solid tumors (not starting in the brain) or fibrolamellar carcinoma (FLC) that have come back or not responded to treatment. It's for children, teens, and young adults (ages 1 to 39).
Minneapolis, MinnesotaAges 1–39 - NCT06414278Recruiting
Spotting early thinking and memory changes with immunotherapy
This study looks at how a special type of immunotherapy called CAR-T therapy might affect your thinking skills, memory, and ability to focus. By checking on patients early and often, the team hopes to find simple ways to detect and manage these side effects sooner.
Minneapolis, MinnesotaAges 18 years+ - NCT07325006Recruiting
How Doctors' Behavior Affects Cancer Distress
This study looks at how doctors' behavior affects the distress cancer patients feel. It's for patients who are getting or recently finished radiation at Mayo Clinic in Rochester.
Rochester, MinnesotaAges 18 years+ - NCT06126276RecruitingPhase 2
Testing neratinib with or without palbociclib for HER2+ solid tumors
This trial tests two targeted drugs—neratinib alone or with palbociclib—for people with HER2-positive solid tumors (other than breast cancer) that have returned or not gone away. The goal is to see if blocking HER2 and CDK4/6 can shrink or slow the tumor.
Bemidji, MinnesotaAges 18 years+ - NCT06723041Recruiting
Acupressure to lower anxiety during cancer treatment
This trial tests if acupressure—a gentle pressure technique on specific points—can help reduce anxiety in people receiving cancer therapy. It compares nurse-led acupressure sessions with learning self-administered acupressure.
Rochester, MinnesotaAges 18 years+ - NCT06513962RecruitingPhase 3
Triptorelin to protect ovaries in young women with cancer
This study tests whether a medicine called triptorelin can protect the ovaries in young women and teens receiving strong chemotherapy for cancer. If you are newly diagnosed with a cancer (other than breast cancer) and are about to get certain chemotherapy drugs, this trial may help preserve your fertility.
Minneapolis, MinnesotaAges Up to 39 years - NCT06353191Recruiting
Blood markers to predict heart problems from cancer therapy
This study looks for early warning signs (biomarkers) of heart damage caused by cancer treatments. It is for people who have had cancer treatment, may have heart issues, or are about to start a treatment that could affect the heart.
Rochester, MinnesotaAges 18 years+ - NCT06198010Recruiting
Managing cancer pain better for survivors
This study tests a new way to help cancer survivors manage pain that started or got worse after their diagnosis. It's for people who rate their pain as 5 or higher on a 0-10 scale and live in rural areas or identify as Hispanic.
Rochester, MinnesotaAges 18 years+ - NCT07291011Recruiting
Mindfulness for underserved cancer patients in Minnesota
This study tests an online mindfulness program (stress-reducing techniques) to help people with cancer who live in rural areas feel better emotionally. It is designed for those who are feeling significant distress.
Rochester, MinnesotaAges Any age - NCT06192875Recruiting
Blood test for early cancer detection: the NOMAD study
This study is testing a new blood test to look for early signs of cancer in people without a past cancer diagnosis. You would give blood, urine, and saliva samples to help researchers see if the test works well.
Rochester, MinnesotaAges 18 years+ - NCT07381179Recruiting
Sharing wisdom and hope with illness
This study invites people with a long-term illness to record their stories and wisdom. You can bring a caregiver if you want. It's about giving hope and sharing experiences.
Rochester, MinnesotaAges 18 years+ - NCT05334069Recruiting
Blood test study for early cancer detection in patients
This study collects blood from people with cancer and people without cancer (or with possible cancer) to test whether new blood tests can detect cancer earlier. Your blood samples help researchers evaluate how well these tests work.
Aitkin, MinnesotaAges 40–75 - NCT05564377RecruitingPhase 2
Find targeted cancer treatments using genetic testing
This study matches people with advanced solid tumors to targeted treatment plans based on genetic testing. It also requires tumor sample testing to help doctors choose the most promising therapy for your specific tumor changes.
Bemidji, MinnesotaAges Any age - NCT03750227RecruitingPhase 3
Radiation before or after brain tumor surgery
This study compares giving focused, high-precision radiation before or after surgery for brain metastases. It aims to see which timing works best to control tumors and improve outcomes.
Rochester, MinnesotaAges 18 years+ - NCT04851119RecruitingPhase 1/Phase 2
Tegavivint for kids and young adults with hard-to-treat solid tumors
This early-phase study tests tegavivint to see how well it works and how safe it is for children and young adults with solid cancers that have come back or are not responding. It may be an option if your tumor type (including certain lymphomas or desmoid tumors) matches the study’s rules.
Minneapolis, MinnesotaAges 1–30 - NCT04870944RecruitingPhase 1/Phase 2
CBL0137 for children with advanced solid or brain tumors
This early-phase study tests CBL0137 in children and teens whose cancer has come back or is not responding to treatment. It is also for some specific hard-to-treat brain tumors, to see if the drug is safe and can work against the cancer.
Minneapolis, MinnesotaAges 1–21 - NCT04901702RecruitingPhase 1/Phase 2
Onivyde plus talazoparib or temozolomide for resistant solid tumors
This trial tests whether adding Onivyde to either talazoparib or temozolomide can shrink or control hard-to-treat (refractory or recurring) cancers in children and young adults. It aims to find safer dosing first, then look at how well the treatment works—especially for Ewing sarcoma.
Minneapolis, MinnesotaAges 1–30 - NCT05112614Recruiting
Study links gut bacteria to cancer treatment response
This study looks at how the bacteria in your gut change during cancer treatment (and during some blood stem cell transplants). It may help researchers understand why some people respond differently and guide better future treatment.
Rochester, MinnesotaAges 18–99
Malignant Solid Neoplasm trials by city in Minnesota
Where these studies are running in Minnesota
Institutions with a site for the recruiting malignant solid neoplasm studies listed above.
- Mayo Clinic · 15 studies
- University of Minnesota Masonic Cancer Center · 5 studies
- Saint John's Hospital - Healtheast · 4 studies
- Sanford Joe Lueken Cancer Center · 4 studies
- Abbott-Northwestern Hospital · 3 studies
- Essentia Health - Deer River Clinic · 3 studies
- Essentia Health Cancer Center · 3 studies
- Essentia Health Hibbing Clinic · 3 studies
What taking part in a malignant solid neoplasm study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Malignant Solid Neoplasm trials in other states
Common questions
- Are there malignant solid neoplasm clinical trials in Minnesota?
- Yes. We're currently tracking 55 recruiting malignant solid neoplasm studies with a site in Minnesota, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a malignant solid neoplasm study in Minnesota?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minnesota to take part?
- Not necessarily. These studies have a site in Minnesota, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a malignant solid neoplasm trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New malignant solid neoplasm studies open in Minnesota regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.