Clinical trials · Minnesota
Malignant Solid Neoplasm clinical trials in Minnesota
We’re tracking 55 recruiting malignant solid neoplasm studies with a site in Minnesota — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Minnesota
- NCT05222620RecruitingPhase 2
SRS methods for untreated brain metastases under 4 cm
This trial compares two stereotactic radiation strategies for patients who have intact (not previously radiated) brain metastases that are limited in size. It aims to see which approach works best in controlling the cancer while reducing side effects.
Albert Lea, MinnesotaAges 18 years+ - NCT05530759Recruiting
Testing blood and tumor samples for diagnostic cancer markers
This study looks at blood and tumor tissue to find signs (markers) that can help diagnose or better understand metastatic cancer. You may be able to join if you’re getting surgery or a biopsy to remove a tumor and there’s a safe way to collect samples.
Rochester, MinnesotaAges 18 years+ - NCT06008392Recruiting
Mayo Clinic cancer genetics research study
This study collects blood, saliva, tumor tissue, or hair samples to look for inherited and tumor-related gene changes that may explain your cancer, guide prevention, or help find better treatments. You can join if you are a Mayo Clinic patient with cancer and your doctor has ordered genetic testing.
Rochester, MinnesotaAges 18 years+ - NCT06015932Recruiting
Group stress management for cancer patients
This trial tests whether group therapy sessions can help cancer patients cope with stress. If you're feeling moderately distressed and have been treated for cancer recently, this program might help you manage those feelings.
Rochester, MinnesotaAges 18 years+ - NCT06075524Recruiting
How PD-1 therapy affects immune cells in advanced cancers
This study looks at how your immune system responds to PD-1/PD-L1 immunotherapy (drugs like Keytruda or Opdivo) for advanced melanoma, lung cancer, and similar cancers. It involves regular blood tests to track your immune cells, which may help doctors understand why these treatments work for some people better than others.
Rochester, MinnesotaAges 18 years+ - NCT06349642Recruiting
Testing a live tumor test for immune therapy response
This trial uses a special test on live tumor samples to see if it can predict how well immune checkpoint inhibitors (a type of immunotherapy) will work for different cancers. It may help doctors choose the best treatment for you.
Rochester, MinnesotaAges 18 years+ - NCT06500455RecruitingPhase 3
Standard vs longer radiation for brain metastases
This trial compares the usual short course of radiation therapy (one session) to a longer course (up to 5 sessions) for people with cancer that has spread to the brain. The goal is to see if the longer course works better and causes fewer side effects.
Chaska, MinnesotaAges 18 years+ - NCT06674811Recruiting
Childhood cancer surgery recovery study
This study looks at how children and young adults recover after surgery for solid tumors. It also includes their caregivers to understand how resilience affects recovery.
Rochester, MinnesotaAges 3–25 - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT06915727RecruitingPhase 3
Testing an imaging drug to see tumors in children having surgery
This study tests a special imaging drug called pafolacianine (Cytalux) that helps doctors see tumors more clearly during surgery. It is for children and teens who have a solid tumor in the body and are already scheduled for tumor removal or biopsy.
Rochester, MinnesotaAges 6 months–17 years - NCT02474160Recruiting
Banking cancer tissue and blood for future research
This study collects and stores leftover or newly taken samples of tissue and blood from people with cancer. The goal is to build a research library that can help investigators study cancer and develop better tests or treatments.
Rochester, MinnesotaAges 2 months+ - NCT02402244Recruiting
Caring registry study for children and young people with cancer
This study keeps a careful record of children, teens, and young adults with cancer (and some related growths) and may follow them over time. It helps researchers better track outcomes and future contact so care can improve.
Minneapolis, MinnesotaAges Up to 25 years - NCT07089927Recruiting
Virtual art therapy for young cancer survivors with depression
This trial tests if virtual art therapy sessions can help adolescents and young adults who have had cancer feel better emotionally and socially. You may be eligible if you have mild or greater depression and had cancer in the past year or finished treatment within the last five years.
Rochester, MinnesotaAges 10–25 - NCT06200116Recruiting
Testing a new tool for outlining healthy tissue in radiation plans
This study tests a new computer tool that helps doctors accurately outline healthy organs during radiation planning. It is for Mayo Clinic staff who already do this work.
Mankato, MinnesotaAges Any age - NCT05538130RecruitingPhase 1
Study medicine for BRAF-mutated advanced solid tumors
This Phase 1 trial studies how PF-07799544 works and what dose is safest in people with advanced cancer that has a specific genetic change called BRAF V600. You may receive it alone or with another treatment, depending on the tumor group, to see if it can treat the cancer.
Saint Louis Park, MinnesotaAges 16 years+ - NCT06295367Recruiting
Cost Communication and Financial Help for Newly Diagnosed Cancer Patients
This study looks at whether talking openly about treatment costs and providing guidance to find financial help can make a difference for people with newly diagnosed solid tumors. If you join, you will be asked to fill out surveys about your experience.
Burnsville, MinnesotaAges Any age - NCT06995898Recruiting
Blood test study for early cancer detection
This study is testing a new blood test that may help find cancer early. You will give blood samples over a year, and researchers will check them for signs of cancer.
Minneapolis, MinnesotaAges 45–75 - NCT06630351Enrolling by invitation
Meaning-centered group therapy for caregiver wellbeing
This study tests whether group therapy focused on meaning and purpose can improve the wellbeing of people caring for someone with advanced cancer or another serious illness. Caregivers will join virtual group sessions and complete questionnaires about their feelings and stress.
Rochester, MinnesotaAges 18 years+ - NCT06395441RecruitingPhase 3
Wisconsin ginseng for cancer-related fatigue
This trial tests whether Wisconsin ginseng can help reduce fatigue in people who have had or are getting treatment for a solid tumor cancer. It aims to improve energy levels and quality of life.
Monticello, MinnesotaAges 18 years+ - NCT05006482RecruitingPhase 3
Geriatric education and care support for older cancer survivors
This study tests whether a structured health education and “older adult care” approach—done with your oncology team—can improve support for people after cancer. It includes older cancer survivors and a chosen caregiver, using in-person or video visits for follow-up.
Saint Paul, MinnesotaAges 18 years+ - NCT06997068RecruitingPhase 2
Drug combination for returning head and neck cancer
This trial tests a combination of three drugs—methotrexate, erlotinib, and celecoxib—for people whose head and neck cancer has come back or spread. It is designed for patients in the rural Midwest who have already had or chosen not to have standard first treatment.
Rochester, MinnesotaAges 18 years+ - NCT05753306RecruitingPhase 2
Robot surgery plus heated chemo for limited spread stomach cancer
This study tests a “robot-assisted” surgery to remove stomach cancer in the belly lining (peritoneum) along with heated chemotherapy placed inside the abdomen. It’s for people whose cancer has spread only in the peritoneum, aiming to control disease when there’s a good chance of removing it all.
Rochester, MinnesotaAges 18–80 - NCT04858009RecruitingPhase 2
Warm chemotherapy placed in the belly for pancreatic cancer spread
This Phase 2 study tests a treatment that warms chemotherapy and delivers it directly into the abdomen to treat pancreatic cancer that has spread to the lining of the belly (peritoneum). You may be eligible if you completed earlier chemotherapy and your body shows signs the cancer is responding, with limited spread in the abdomen.
Rochester, MinnesotaAges 18–80 - NCT07525141RecruitingPhase 1
Testing JNJ-1761981 for advanced solid tumors
This early-stage trial tests a new drug called JNJ-1761981 in people with solid tumors (cancers that form in organs or tissues, excluding brain tumors) that have spread or returned after standard treatment. The study aims to find the right dose and see how well the drug works.
Rochester, MinnesotaAges 18 years+
Malignant Solid Neoplasm trials by city in Minnesota
Where these studies are running in Minnesota
Institutions with a site for the recruiting malignant solid neoplasm studies listed above.
- Mayo Clinic · 19 studies
- Monticello Cancer Center · 4 studies
- Hennepin County Medical Center · 3 studies
- Mayo Clinic Health System in Albert Lea · 3 studies
- Mayo Clinic Health System in Mankato · 3 studies
- Regions Hospital · 3 studies
- Fairview Clinics and Surgery Center Maple Grove · 2 studies
- Fairview Southdale Hospital · 2 studies
What taking part in a malignant solid neoplasm study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Malignant Solid Neoplasm trials in other states
Common questions
- Are there malignant solid neoplasm clinical trials in Minnesota?
- Yes. We're currently tracking 55 recruiting malignant solid neoplasm studies with a site in Minnesota, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a malignant solid neoplasm study in Minnesota?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minnesota to take part?
- Not necessarily. These studies have a site in Minnesota, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a malignant solid neoplasm trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New malignant solid neoplasm studies open in Minnesota regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.