Clinical trials
Medications for Opioid Use Disorder clinical trials
Below are recruiting medications for opioid use disorder clinical trials, each written for real people, not researchers. We’re tracking 226 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05940324RecruitingPhase 2
Ketamine study for OCD after prior treatment failed
This Phase 2 study tests how ketamine may work quickly in people with obsessive-compulsive disorder (OCD), especially after at least one standard treatment didn’t help. If you join, you’ll need to follow study procedures like fasting before the experimental visit and not enrolling in other medication trials during the study.
Stanford, CaliforniaAges 18–65 - NCT05555485Recruiting
Check if ear stimulation can help chronic pain and reduce opioids
This study tests whether a device that stimulates the ear (through the skin) can reduce chronic pain and help people lower their opioid pain medicine. It may help you manage pain with less opioid use if you meet their safety and medication criteria.
Galveston, TexasAges 18–65 - NCT06442566RecruitingPhase 1/Phase 2
Enhancing opioid therapy for chronic pain with buprenorphine, counseling, and brain stimulation
This study is testing whether adding a medication (buprenorphine), counseling, and a type of brain stimulation (TMS) can improve long-term opioid therapy for chronic pain. If you have been taking prescription opioids daily for at least 3 months and have extra risk factors for opioid-related problems, this trial may offer you new ways to manage pain and reduce risks.
Charleston, South CarolinaAges 18 years+ - NCT06425224RecruitingPhase 3
TENS therapy for premature ejaculation
This trial tests if a painless electrical nerve stimulation (TENS) treatment can help men with premature ejaculation last longer and feel more in control. It's for men who have had this condition for at least 6 months and are in a stable relationship.
Mexico CityAges 18–62 - NCT07552766RecruitingPhase 4
Lidocaine infusion to reduce opioid use in arm fracture surgery
This study tests whether giving a pain-relieving medication called lidocaine through an IV during arm fracture surgery can reduce how much opioid pain medication (like morphine) children need after surgery. The goal is to help manage pain better while using fewer opioids.
Wilmington, DelawareAges 3–18 - NCT07712887Recruiting
Studying how IQOS users puff across device models
This study looks at how people who regularly use IQOS inhale from different versions of the device. It aims to understand how the feeling and pattern of use change between models.
Beirut, BeirutAges 18–65 - NCT07217197Enrolling by invitation
A monitor to detect breathing problems after surgery
This trial tests a new respiratory monitoring system to see if it can detect and predict opioid-induced respiratory depression (OIRD) — when pain medicines slow your breathing too much — in patients recovering from surgery. The monitor uses a face mask, nasal cannula, and small sensors to track breathing continuously, so that doctors can step in early if there is a problem.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05565833RecruitingPhase 2
Online sleep program for insomnia and thinking problems
This Phase 2 study tests an internet-based sleep program to help older adults with insomnia and related thinking difficulties. It may help improve sleep and reduce how much tiredness and sleep disruption affect daily life.
Charlottesville, VirginiaAges 65 years+ - NCT07026786Recruiting
Mindfulness for recovery after colorectal surgery
This study tests whether adding mindfulness sessions to your standard recovery plan helps you heal better after bowel surgery. You'll use a phone or tablet app to guide your mindfulness practice during your hospital stay.
Cleveland, OhioAges 18 years+ - NCT05988710RecruitingPhase 4
Low-dose buprenorphine for pain in opioid-naive adults
This study tests a low-dose form of buprenorphine (a medicine for pain) placed inside the cheek. It is designed for people who have never taken opioids before, to see how well it works for pain and how likely it is to be misused.
Nashville, TennesseeAges 18–65
Hear when a new Medications for Opioid Use Disorder trial opens
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Common questions
- Are there clinical trials for medications for opioid use disorder?
- Yes. Clin2 currently lists 226 recruiting medications for opioid use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a medications for opioid use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a medications for opioid use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.