Clinical trials
Mental Health Disorder clinical trials
Below are recruiting mental health disorder clinical trials, each written for real people, not researchers. We’re tracking 509 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07754721Recruiting
Diet and lifestyle program for chronic acid reflux
This study tests a comprehensive program that combines diet and lifestyle changes to help people with chronic acid reflux (heartburn, acid regurgitation, or chest pain) feel better. It looks at how these changes can improve your overall health and reduce symptoms.
Hualien City, TaiwanAges 18–79 - NCT06796062RecruitingPhase 2
Psilocybin for opioid use disorder
This study tests whether psilocybin can help people who want to stop using opioids and are already in treatment. Eligible participants receive a single dose of psilocybin in a supervised setting and are followed to see if it reduces opioid use.
Albuquerque, New MexicoAges 18–65 - NCT06843213Recruiting
Peer-led health resilience program for opioid use disorder
This trial tests a peer-led program to help people with opioid use disorder build resilience and coping skills while they are in the hospital. The program is designed to support recovery and improve health outcomes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07180537Recruiting
Health course for joint and mood conditions
This study tests an online health course that helps improve diet and self-care to support cell health and wellbeing. It is for people with certain rheumatological conditions like rheumatoid arthritis, lupus, or psoriatic arthritis, who also have mood concerns.
Iowa City, IowaAges 18–100 - NCT07278440Recruiting
Exercise program for brain tumor patients and their partners
This study tests if a home exercise program can improve mental and physical health for people with brain tumors and their live-in partners. Both of you will be guided through exercise sessions together over video.
Portland, OregonAges 18 years+ - NCT07754929Recruiting
Digital support for prostate cancer survivors' sexual and mental health
This study tests a smartphone-based program designed to help prostate cancer survivors improve their mental and sexual health. It may offer a convenient way to get support without visiting a clinic.
PortoAges 18 years+ - NCT06338280RecruitingPhase 2
Observing methadone treatment remotely
This study tests if using a smartphone app to watch you take your methadone works as well as going to a clinic every day. It might make treatment easier for you.
Chicago, IllinoisAges 18–64 - NCT05956392Recruiting
Personal plan to reduce kids’ screen time for better sleep
This trial tests a personalized program to help children use screens less in order to improve sleep, mood, and brain health. It’s for children who regularly sleep under 8 hours on school nights and spend more than 2 hours per day on media.
SingaporeAges 6–12 - NCT05703412Enrolling by invitation
Text or app check-ins after discharge for serious mental illness
This study tests an mHealth (phone-based) program that helps people with serious mental illness after leaving the hospital. It may help you stay connected to care and support in the community after discharge.
Providence, Rhode IslandAges 18 years+ - NCT06940986Recruiting
Holistic pain self-management for military health system patients
This trial tests a holistic pain self-management program for people with long-term muscle or bone pain. It aims to help you take control of your pain through education and support, without relying only on medications.
Fairbanks, AlaskaAges 18 years+ - NCT06743282Enrolling by invitation
Study on mobile support for substance use in primary care
This trial tests a program called Senyo Health that provides support through text messages and video calls for people with substance use concerns. It aims to help you manage your substance use while working with your primary care doctor.
Scottsdale, ArizonaAges 18 years+ - NCT06356558Recruiting
Making recovery programs easier for patients with limited health literacy
This study is testing ways to improve recovery programs for patients who may have trouble understanding health information. It aims to make these programs easier to follow, so patients can have better recovery after surgery.
Birmingham, AlabamaAges 18 years+ - NCT06781801Recruiting
Heart and metabolic health for severe mental illness
This trial tests a long-term program to improve heart and metabolic health in adults with schizophrenia or related disorders. It may help reduce health risks often linked with severe mental illness.
GothenburgAges 18 years+ - NCT07455526Recruiting
Help to quit smoking for veterans with mental illness
This program helps veterans who have a serious mental illness and use tobacco to get more support for quitting, such as connecting them with treatment options during their mental health visits.
Baltimore, MarylandAges Any age - NCT07224490RecruitingPhase 1
Kisspeptin test for brain function after COVID-19
This study tests how the brain's reproductive hormone system works after a COVID-19 infection using a substance called kisspeptin. It may help explain symptoms like changes in periods or hormone levels in people with long COVID.
Boston, MassachusettsAges 18–60 - NCT06982820Recruiting
Brain training therapy for depression with loss of interest
This trial tests a new type of brain training (self-neuromodulation) to help people with major depression who also have a significant loss of interest or pleasure (anhedonia). If you qualify, you may get a non-invasive treatment that uses real-time brain feedback to improve symptoms.
Providence, Rhode IslandAges 22–75 - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT06854328Recruiting
Prism PTSD study for adolescents
This trial tests a new non-invasive device that uses brain imaging to help treat PTSD symptoms in teens and young adults. It may be a good option if you haven't yet completed a full course of trauma-focused therapy.
New York, New YorkAges 12–21 - NCT06404320Recruiting
Exercise program for treatment-resistant depression
This study tests whether a physical activity program can help adults whose depression hasn’t improved after trying at least two antidepressants. If you’re sedentary, between 18 and 65, and have treatment-resistant depression, this program might offer a new way to feel better through exercise.
Toronto, OntarioAges 18–65 - NCT06889831Recruiting
Paths to sexual health and recovery for women in the justice system
This study tests a program to help women with substance use and unmet contraception needs who have been involved with the criminal legal system in the past year. The goal is to see if the program supports both recovery and family planning choices.
Teaneck, New JerseyAges 18–44 - NCT06665984Recruiting
Greater Houston pediatric bipolar registry study
This study is creating a registry to learn more about bipolar disorder in children and teens. It includes youth who have bipolar disorder and those who have a parent with bipolar disorder, as well as healthy youth for comparison.
Houston, TexasAges 6–17 - NCT05033028RecruitingPhase 3
Using a smartphone to support opioid addiction recovery
This Phase 3 study tests whether using smartphones can help people with opioid-use disorder stick with treatment and recover more successfully. It focuses on people starting or already in treatment using methadone or buprenorphine, with support delivered through the study app or messages.
Piscataway, New JerseyAges 18–85 - NCT07290738Recruiting
TMS for negative symptoms in schizophrenia
This study tests whether a non-invasive brain stimulation technique called TMS can help reduce negative symptoms in people with schizophrenia. These symptoms include things like lack of motivation, limited speech, and not expressing emotions.
Houston, TexasAges 18–60 - NCT06845488Recruiting
Using virtual reality to treat social anxiety in autism
This trial tests whether virtual reality exercises can help reduce social anxiety in adults with autism. Participants will practice social situations in a safe, computer-based environment.
Houston, TexasAges 18 years+
Hear when a new Mental Health Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for mental health disorder?
- Yes. Clin2 currently lists 509 recruiting mental health disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.