Clinical trials
Mental Health Disorder clinical trials
Below are recruiting mental health disorder clinical trials, each written for real people, not researchers. We’re tracking 521 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05304104Recruiting
Eating disorder care program for vets with binge problems
This trial looks at how to build a more fair and easy-to-access system of care for eating disorders within the VA and related groups. You may be able to take part if you are a VA user and have bulimia or binge eating, and can safely complete surveys and treatment planning.
West Haven, ConnecticutAges 18 years+ - NCT06781801Recruiting
Heart health study for people with serious mental illness
This study tests whether a long-term program can improve heart and metabolic health in people with serious mental illness. It may be a good fit if you have a schizophrenia spectrum disorder and want to join a comprehensive health improvement trial.
GothenburgAges 18 years+ - NCT07224490RecruitingPhase 1
Kisspeptin test for brain function after COVID-19
This study tests how the brain's reproductive hormone system works after a COVID-19 infection using a substance called kisspeptin. It may help explain symptoms like changes in periods or hormone levels in people with long COVID.
Boston, MassachusettsAges 18–60 - NCT06982820Recruiting
Brain training therapy for depression with loss of interest
This trial tests a new type of brain training (self-neuromodulation) to help people with major depression who also have a significant loss of interest or pleasure (anhedonia). If you qualify, you may get a non-invasive treatment that uses real-time brain feedback to improve symptoms.
Providence, Rhode IslandAges 22–75 - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT06854328Recruiting
Prism PTSD study for adolescents
This trial tests a new non-invasive device that uses brain imaging to help treat PTSD symptoms in teens and young adults. It may be a good option if you haven't yet completed a full course of trauma-focused therapy.
New York, New YorkAges 12–21 - NCT06665984Recruiting
Greater Houston pediatric bipolar registry study
This study is creating a registry to learn more about bipolar disorder in children and teens. It includes youth who have bipolar disorder and those who have a parent with bipolar disorder, as well as healthy youth for comparison.
Houston, TexasAges 6–17 - NCT05033028RecruitingPhase 3
Using a smartphone to support opioid addiction recovery
This Phase 3 study tests whether using smartphones can help people with opioid-use disorder stick with treatment and recover more successfully. It focuses on people starting or already in treatment using methadone or buprenorphine, with support delivered through the study app or messages.
Piscataway, New JerseyAges 18–85 - NCT06404320Recruiting
Exercise program for treatment-resistant depression
This study tests whether a physical activity program can help adults whose depression hasn’t improved after trying at least two antidepressants. If you’re sedentary, between 18 and 65, and have treatment-resistant depression, this program might offer a new way to feel better through exercise.
Toronto, OntarioAges 18–65 - NCT06889831Recruiting
Paths to sexual health and recovery for women in the justice system
This study tests a program to help women with substance use and unmet contraception needs who have been involved with the criminal legal system in the past year. The goal is to see if the program supports both recovery and family planning choices.
Teaneck, New JerseyAges 18–44 - NCT07290738Recruiting
TMS for negative symptoms in schizophrenia
This study tests whether a non-invasive brain stimulation technique called TMS can help reduce negative symptoms in people with schizophrenia. These symptoms include things like lack of motivation, limited speech, and not expressing emotions.
Houston, TexasAges 18–60 - NCT06444256RecruitingPhase 2
Testing a sleep medication for people with stimulant use
This trial tests whether a medication that blocks a brain chemical involved in wakefulness can help people with stimulant use disorder sleep better. If you use cocaine or methamphetamine and have trouble sleeping, this study may be an option.
Houston, TexasAges 18–65 - NCT06845488Recruiting
Using virtual reality to treat social anxiety in autism
This trial tests whether virtual reality exercises can help reduce social anxiety in adults with autism. Participants will practice social situations in a safe, computer-based environment.
Houston, TexasAges 18 years+ - NCT07390786Recruiting
Family support program after ICU stay
This study tests a collaborative care program for family members of ICU recovery patients, designed to improve mental health support after a loved one's hospitalization.
Charleston, South CarolinaAges 18 years+ - NCT05004987RecruitingPhase 4
Study brain and blood changes in older adults with depression
This study looks at how a brain protein linked to Alzheimer’s disease changes over time in older adults who have major depression but no major memory problems. It involves brain scans, blood and urine tests, and a spinal fluid sample to better understand the connection between depression and brain aging.
New York, New YorkAges 60 years+ - NCT06662357Recruiting
Family Connections mental health and substance use support for youth
This trial provides integrated mental health and substance use assessments for children and teens ages 3 to 18. It's designed for families who've been referred by their primary care doctor and have MassHealth insurance.
Cambridge, MassachusettsAges 3–18 - NCT06821230Recruiting
Mindfulness for Parkinson's patients and their caregivers
This study tests whether a dyadic mindfulness program can help both people with Parkinson's disease and their caregivers manage negative emotions. You and your care partner would attend sessions together to learn mindfulness techniques.
Hong KongAges 18 years+ - NCT06923722Recruiting
Can eating grapes help protect your brain during stress?
This study tests whether eating grapes every day for a few weeks can reduce the negative effects of mental stress on your brain and blood vessels. If you are a healthy young adult who experiences stress, you may be able to join.
Birmingham, West MidlandsAges 18–40 - NCT01980147Recruiting
Skills for Wellness program for youth coping with mental health risks
This trial tests a structured skills program to help children and teens (ages 9–21) cope with early mental health warning signs such as anxiety, mood swings, or unusual thoughts. It may help participants build practical coping tools and well-being.
Halifax, Nova ScotiaAges 9–21 - NCT07592195Recruiting
Breathing and aerobic exercise for men in drug recovery
This study tests whether breathing exercises and aerobic exercise (like walking or jogging) improve physical and mental health in men recovering from substance use. You'd attend supervised exercise sessions twice a week for 8 weeks and complete health questionnaires.
LuzhouAges 18–50 - NCT07411222Recruiting
Emotional Eating, Sleep, and Metabolic Health Study
This study examines how emotional eating, sleep quality, and mental state relate to metabolic syndrome (a group of conditions like high blood pressure, high blood sugar, and extra belly fat) in people with stable schizophrenia or bipolar disorder. It aims to help understand and improve overall health.
Bolu, BoluAges 18–65 - NCT04226898RecruitingPhase 2
Synbiotic supplement to lessen schizophrenia symptoms
This Phase 2 trial tests whether a “synbiotic” supplement (a mix of probiotics and prebiotics) can reduce symptoms of schizophrenia or schizoaffective disorder. It may help by targeting gut-related immune and inflammation pathways that could affect brain symptoms.
Batlimore, MarylandAges 18–65 - NCT04877093RecruitingPhase 3
Low-dose clonidine for PTSD nightmares in veterans
This Phase 3 study tests whether low-dose clonidine can reduce PTSD symptoms and especially nightmares in U.S. veterans. You’d be screened for PTSD severity and current treatments, then asked to visit the clinic as scheduled to see if the treatment helps.
Wauwatosa, WisconsinAges 18 years+ - NCT05871606RecruitingPhase 1
Breathing nitric oxide during clot-removal for stroke
This Phase 1 study tests whether inhaled nitric oxide (a gas breathed through a ventilator) can improve outcomes in people having a specific kind of emergency stroke procedure to remove a clot from the brain. It focuses on patients who need general anesthesia for the clot-removal procedure and have imaging results that suggest salvageable brain tissue.
Charlotte, North CarolinaAges 18–80
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Common questions
- Are there clinical trials for mental health disorder?
- Yes. Clin2 currently lists 521 recruiting mental health disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.