Clinical trials
Mental Health Outcomes clinical trials
Below are recruiting mental health outcomes clinical trials, each written for real people, not researchers. We’re tracking 74 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06518720RecruitingPhase 2
Psilocybin for Chronic Nerve Pain and Depression
This trial tests whether psilocybin (a psychedelic medication) can help people who have both chronic nerve pain and depression that hasn't responded to standard treatments. The goal is to see if it can reduce pain and improve mood.
Toronto, OntarioAges 18–65 - NCT05012072Recruiting
Lifestyle coaching to lower pregnancy stress and risk
This study tests a lifestyle coaching program to help reduce stress and improve emotional wellbeing during pregnancy. It may help lower risks for the baby by supporting healthier daily routines and mental health.
Webster, TexasAges 18–45 - NCT05363397RecruitingPhase 2
Adjunctive TBO-309 added to stroke clot removal treatment safety
This Phase 2 trial studies whether adding TBO-309 to standard emergency treatment for acute ischemic stroke is safe and tolerable. It may help researchers see if the added drug can be given without causing excessive side effects alongside clot-busting and/or clot-removal procedures.
Camperdown, New South WalesAges 18 years+ - NCT06768749Recruiting
Melatonin lotion for better sleep and mood
This trial tests whether using a scented melatonin lotion before bed can improve sleep and reduce anxiety or depression symptoms. It may be a good fit if you have mild sleep problems and some mood symptoms but are not currently taking medication for them.
Redlands, CaliforniaAges 18–21 - NCT06773338Recruiting
Can playing Tetris improve mental health for migrants?
This study tests if playing the game Tetris can help reduce stress and improve mood for Arabic-speaking immigrants who have applied for asylum. You would play Tetris a few times and report how you feel.
The Hague, NLAges 18 years+ - NCT06973512Recruiting
Brain stimulation for severe addiction
This trial tests a new brain stimulation approach for people with severe addiction that hasn't gotten better with other treatments. It uses deep brain stimulation guided by brain mapping to try to reduce cravings and help you stay abstinent.
Toronto, OntarioAges 25–65 - NCT02543983RecruitingPhase 2
Brain scan and ketamine study for suicidal thoughts
This trial studies how ketamine affects the brain in people dealing with suicidal thoughts or an active suicide crisis. It uses questionnaires, consent testing, and brain imaging to look for biological changes that may relate to symptom improvement.
Bethesda, MarylandAges 18–70 - NCT07480668Recruiting
Aromatherapy for emotional wellness during IVF
This study tests whether inhaling lavender essential oil can help reduce anxiety, stress, and depression for women waiting for IVF. You may benefit if you are feeling some emotional distress and are not using other mind-body or herbal treatments.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT05674617Recruiting
PTSD treatment for Veterans with serious mental illness
This trial tests a PTSD treatment approach for Veterans who also have a serious mental illness, aiming to improve day-to-day functioning. It includes Veterans who receive outpatient mental health care through the VA and have confirmed PTSD in the last month.
Baltimore, MarylandAges 18 years+ - NCT07301853Recruiting
Long-term follow-up for liver transplant patients and living donors
This study follows liver transplant recipients and living donors over time to track their health outcomes. It aims to understand their recovery and long-term wellbeing.
Hangzhou, ZhejiangAges 18 years+ - NCT06655337Recruiting
Testing a smartphone app for managing hospital discharge
This study tests whether a smartphone app called Medidux helps you manage your symptoms and discharge from the hospital if you came in with coughing, back pain, or belly discomfort. You'll use the app to report how you're feeling, and the care team can check in with you after you leave.
Horgen, Canton of ZurichAges 18 years+ - NCT07479758Recruiting
Brain scans and vision tests for severe mental illness
This study uses advanced MRI scans and visual perception tests to learn more about severe mental disorders like depression, schizophrenia, and bipolar disorder. It aims to improve diagnosis and treatment outcomes.
Hangzhou, ZhejiangAges 18–45 - NCT06951542Enrolling by invitation
Reducing HIV and mental health stigma in Malawi
This study tests a program to reduce stigma for people living with HIV who also have symptoms of depression. It aims to improve mental health and HIV outcomes.
MulanjeAges 18 years+ - NCT04017286Recruiting
Pregnancy mental health survey and baby development outcomes study
This study looks at how a pregnant person’s mental well-being during pregnancy relates to their child’s later behavior and development. It mainly involves questionnaires and comparing outcomes, and it may help researchers understand what pregnancy mental health supports best.
Chongqing, Chongqing MunicipalityAges 3 months–6 years - NCT07125209Recruiting
Chemotherapy and thinking for ovarian cancer
This study looks at how chemotherapy given before surgery for ovarian cancer may affect thinking and memory. It helps doctors understand the cognitive side effects of treatment so they can better support patients.
Madison, WisconsinAges 18 years+ - NCT07577947Recruiting
Digital tracking to help treat pregnancy and postpartum depression
This study tests whether wearing an Apple Watch and using a smartphone app can help doctors better understand and treat depression during pregnancy and after birth. You'll receive depression treatment through the study while the app and watch track your daily patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT04428164Enrolling by invitation
Improving pain and sleep with non-drug hospital supports
This trial looks at non-medication ways to improve comfort (pain) and sleep for hospital patients. You may be asked to use study supports and complete short surveys.
Dallas, TexasAges 20 years+ - NCT06996249Recruiting
Thoracic cancer data collection study
This study collects medical information from people with suspected or confirmed thoracic cancer. The goal is to learn more about these cancers and improve future care.
Ede, GelderlandAges 18 years+ - NCT07222839Enrolling by invitation
Video education to ease heart surgery anxiety
This study tests whether watching an immersive video before surgery can help reduce anxiety in people having planned open heart surgery. If you qualify, you'll watch a short virtual reality video to see if it makes you feel more relaxed and prepared.
Miami, FloridaAges 18 years+ - NCT06083649Recruiting
Dental education: AI vs. human counseling for gum disease
This trial compares two ways of teaching about dental care—AI-assisted education versus speaking with a counselor—to see which one helps people with gum disease better control plaque and improve treatment outcomes.
Kaohsiung CityAges 35–65 - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT05074732Recruiting
Study of forensic mental health admissions after a service move
This study looks at all adult admissions to Ireland’s National Forensic Mental Health Service during a specific time window. It may help improve how the new forensic service at Portrane runs in the future.
DublinAges 18 years+ - NCT06999395Recruiting
Virtual program for pelvic pain with vestibulodynia
This study tests whether a virtual program can help reduce pelvic pain and improve sexual experiences in people with a specific type of pain called provoked vestibulodynia. It is a completely online program, so you can participate from home.
Kingston, OntarioAges 18 years+ - NCT04335994Recruiting
Home sleep testing for people with memory trouble
This study looks at how well home sleep apnea testing works for people with cognitive impairment (memory/thinking problems) to help improve outcomes. You may be asked to do a home sleep test (and possibly an in-lab test) and will involve a caregiver if needed.
Toronto, OntarioAges Any age
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Common questions
- Are there clinical trials for mental health outcomes?
- Yes. Clin2 currently lists 74 recruiting mental health outcomes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health outcomes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health outcomes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.