Clinical trials
Mental Health clinical trials
Below are recruiting mental health clinical trials, each written for real people, not researchers. We’re tracking 724 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01778504Recruiting
Study of childhood behavioral and psychiatric disorders
This study looks at brain, behavior, and genetic factors in people with neuropsychiatric or developmental disorders, as well as their biological relatives. It may help researchers better understand these conditions and find new ways to diagnose or treat them.
Bethesda, MarylandAges 4 weeks–99 years - NCT07716969Recruiting
Reducing time without treatment for psychosis
This trial tests a program to help people get treatment faster for psychosis. It is for patients who have started OPUS treatment within the last 9 months and may have a schizophrenia-related condition.
Copenhagen, DenmarkAges 18–35 - NCT06399991Recruiting
Improving mental health care in Malawi clinics
This study is testing a new way to help clinics in Malawi better support patients with mental health needs. If you are an adult patient at a participating clinic who has recently had symptoms of depression or anxiety, you may be eligible.
ChiradzuluAges 18 years+ - NCT03388606Recruiting
Studying adolescent depression and how to treat it
This study looks closely at how depression shows up in teens and tests approaches to treatment. It may help teens and families better understand depression and get access to structured care as part of research.
Los Angeles, CaliforniaAges 11–25 - NCT03224091Recruiting
Study of people with eating disorders followed over time
This study follows people with eating disorders over time to better understand symptoms and how they change. You may benefit by contributing to research that can improve care and support.
Ballerup Municipality, Capitol RegionAges 18–65 - NCT03304665Recruiting
Healthy volunteers needed for brain and behavior research studies
This study recruits healthy adults to help researchers run mental health and brain-related experiments. It may help future studies by improving how they measure brain function and behavior.
Bethesda, MarylandAges 18–70 - NCT03906435Recruiting
Cognitive therapy to prevent problems for very premature NICU babies
This study offers a counseling approach to help prevent “Vulnerable Child Syndrome” in babies born very early and cared for in the NICU. It focuses on support during the early months after birth and compares outcomes for families getting the therapy versus usual support.
Dallas, TexasAges Any age - NCT03973268RecruitingPhase 1
Ketamine study to understand treatment response in hard-to-treat depression
This early-stage study tests ketamine and looks at what brain changes may explain why it helps people with major depression that hasn’t improved with usual treatments. You may be asked to stay in the hospital and complete detailed interviews, mood rating scales, and brain imaging.
Bethesda, MarylandAges 18–70 - NCT04877977Recruiting
Long-Term Follow-Up for People With Mood Disorders
This study follows people with mood disorders over a long time to better understand how symptoms and functioning change. You may be able to join if you already agreed to take part in an earlier mood/anxiety study and you meet basic participation needs.
Bethesda, MarylandAges 18–99 - NCT04033679Recruiting
Brain stimulation to help people stay on schizophrenia medications
This study tests whether a non-invasive brain stimulation treatment can improve medication adherence in people with schizophrenia or schizoaffective disorder. If it helps you take meds more reliably, it may also support more stable mental health over time.
Toronto, OntarioAges 18 years+ - NCT04159662Recruiting
Brain scans to study thinking in schizophrenia and depression
This study uses brain imaging to better understand how thinking works in people with schizophrenia or major depression. Your results may help researchers learn what brain patterns match different thinking and symptoms.
Ottawa, OntarioAges 18–60 - NCT04230421Recruiting
Smartphone treatment program for bipolar disorder
This trial is testing a smartphone-based treatment approach for people living with bipolar disorder. It may help by delivering support and care tools in a way that’s easier to use day to day.
CopenhagenAges 18 years+ - NCT04325958Recruiting
Test how cannabis affects driving in different age groups
This study looks at how smoked cannabis changes driving performance when compared across two age groups. It may help researchers understand safety risks and differences by age.
Toronto, OntarioAges 19–45 - NCT04373629Recruiting
Testing how flexible appearance worries may change in BDD
This study looks at whether training can change how people with body appearance worries (including body dysmorphic disorder) perceive faces or the head. It may help researchers understand new ways to reduce distress related to these concerns.
Toronto, OntarioAges 18–40 - NCT04396873RecruitingPhase 1
PET brain scan study of inflammation markers in neurodegeneration
This Phase 1 study tests a PET scan to measure inflammation-related changes in the brain using a medication called ketoprofen. It may help researchers understand which people with certain brain diseases could benefit from treatments aimed at inflammation.
Bethesda, MarylandAges 18–99 - NCT04447742Recruiting
Study of how healthy babies’ gut microbes develop from birth
This study follows pregnant people from about 20 weeks until delivery, to understand how gut microbes (tiny organisms in the intestines) develop in healthy babies. It may help researchers learn how early-life gut development affects health later on.
BernAges 18–45 - NCT04478838RecruitingPhase 4
Alternate-day antipsychotic dosing for schizophrenia
This trial looks at whether taking an antipsychotic every other day can keep symptoms controlled in adults with schizophrenia or another psychotic disorder. It may help some people avoid daily dosing, but it requires specific medication stability and screening checks.
Toronto, OntarioAges 18 years+ - NCT04499066Recruiting
Mental health study during early pregnancy in Guangzhou
This study follows pregnant people in early pregnancy to better understand mental health during the perinatal (pregnancy and around delivery) period. It may help the clinic improve support for mental well-being before and after birth.
Guangzhou, GuangdongAges Any age - NCT04512755Recruiting
AIMS medical outcomes study for new or established patients
This is an observational study where the AIMS team collects information from patients during a first visit or ongoing care. It helps the clinic understand patients’ experiences and outcomes, but it does not test a new medicine.
Seattle, WashingtonAges Any age - NCT04526743Recruiting
Eating habits and weight changes after weight-loss surgery
This study looks at how eating behaviors change over time after bariatric (weight-loss) surgery. It may help researchers understand why some people lose more weight than others and how to improve support after surgery.
BarcelonaAges 18–70 - NCT04539951RecruitingPhase 2
Trial for newly treated obsessive-compulsive disorder
This phase 2 study tests an OCD treatment strategy for people who have not yet had OCD medications or recent OCD therapy. It aims to reduce OCD symptoms, especially for those with moderate-to-severe symptom levels.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT04569448RecruitingPhase 3
Brexpiprazole for bipolar depression that won’t improve
This Phase 3 study tests whether brexpiprazole can help treat bipolar depression that has not responded to previous treatments. It compares the study medicine to a placebo (inactive pill) for people with bipolar I or II depression.
Hamilton, OntarioAges 18–75 - NCT04629352Recruiting
tDCS brain-stimulation for hearing voices in schizophrenia
This study tests whether a non-invasive brain-stimulation treatment (tDCS) can improve response to care in people who experience clinically significant hearing voices. It may help by changing brain activity, aiming to reduce or improve auditory hallucinations.
Bengaluru, KarnatakaAges 18–45 - NCT04631042Recruiting
Study how the brain relates to impulsivity and compulsivity
This study looks at how brain function and structure relate to impulsive and compulsive behaviors. It may help researchers understand what drives these behaviors and who may benefit from future mental health treatments.
Bethesda, MarylandAges 6–80
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Common questions
- Are there clinical trials for mental health?
- Yes. Clin2 currently lists 724 recruiting mental health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.