Clinical trials
Mental Health clinical trials
Below are recruiting mental health clinical trials, each written for real people, not researchers. We’re tracking 700 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06828276Recruiting
Online therapy for Farsi and Dari speaking young migrants
This study tests if a culturally adapted online therapy program helps reduce anxiety and depression in young Farsi or Dari speaking migrants. You would use your computer or phone for 6 to 10 weeks at home.
StockholmAges 15–29 - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT05012072Recruiting
Lifestyle coaching to lower pregnancy stress and risk
This study tests a lifestyle coaching program to help reduce stress and improve emotional wellbeing during pregnancy. It may help lower risks for the baby by supporting healthier daily routines and mental health.
Webster, TexasAges 18–45 - NCT06795581RecruitingPhase 1
Brain imaging study for alcohol use disorder
This study uses a special brain scan (PET) to look at a protein called PDE4B in people with alcohol use disorder. The goal is to better understand how alcohol affects the brain, which may lead to new treatments.
Bethesda, MarylandAges 18–70 - NCT05701111Recruiting
School-based treatment for teens with trauma symptoms
This study tests a school-based approach to help teens who have experienced trauma and now have post-trauma symptoms. It also collects emotional and physical (biologic) information to understand how treatment may help.
Palo Alto, CaliforniaAges 11–17 - NCT06798324RecruitingPhase 4
Brain stimulation plus smoking cessation medication for quitting smoking
This trial tests whether combining brain stimulation (tDCS) with a smoking cessation medication (varenicline) helps people quit smoking. You would attend daily visits for two weeks.
Toronto, OntarioAges 18–85 - NCT06792175Enrolling by invitation
Using speech to detect mental health conditions
This study uses a computer program to listen to your speech and see if it can help detect mental health or neurodevelopmental conditions. It may help find new ways to diagnose conditions like ADHD, anxiety, depression, and others earlier.
Brookline, MassachusettsAges 13–60 - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT06783283Recruiting
Brain stimulation to improve memory in mild cognitive impairment
This trial tests whether a gentle electrical brain stimulation technique called tACS can improve working memory in people with mild cognitive impairment (MCI). If you have MCI due to early Alzheimer's, this study may help find new ways to boost memory.
Toronto, OntarioAges 60 years+ - NCT06792227Enrolling by invitation
Family-based eating disorder treatment at home for teens
This trial tests a family-based treatment program for teens with eating disorders and other mental health conditions, delivered at home. It aims to help families support recovery together.
Almelo, OverijsselAges 12–18 - NCT06782321Recruiting
Virtual emotional support after stroke
This study tests a virtual program to help with emotional recovery like anxiety or sadness after a stroke. You can join from home using your own device.
Charleston, South CarolinaAges 21 years+ - NCT06777823Recruiting
Social media and mental health study for girls aged 10-11
This study looks at how social media affects the mental health of girls going through puberty. It tests whether sensitivity to rejection and puberty stage make some girls more vulnerable to social media experiences.
St Louis, MissouriAges 10 years+ - NCT06780917Recruiting
Online cognitive testing for older adults with depression or memory concerns
This study tests whether an online cognitive assessment platform (Creyos) is valid for older adults with major depression or mild cognitive impairment. Participants will complete brain games or puzzles to see how well the online tool measures thinking skills.
Toronto, OntarioAges 60 years+ - NCT06773949Recruiting
Exercise before rTMS for hard-to-treat depression
This trial tests if doing exercise before repetitive transcranial magnetic stimulation (rTMS) can improve depression symptoms in people who haven't gotten better with standard treatments.
Ottawa, OntarioAges 18–75 - NCT06776523Recruiting
Psychological help study for refugees in Switzerland
This study tests a brief psychological program (Problem Management Plus, or PM+) to see if it helps refugees and asylum seekers feel better. If you are feeling stressed, anxious, or down, this may be an option for you.
ZurichAges 16 years+ - NCT06768749Recruiting
Melatonin lotion for better sleep and mood
This trial tests whether using a scented melatonin lotion before bed can improve sleep and reduce anxiety or depression symptoms. It may be a good fit if you have mild sleep problems and some mood symptoms but are not currently taking medication for them.
Redlands, CaliforniaAges 18–21 - NCT06760325Enrolling by invitation
Home visits for mental health support in severe COPD
This trial studies whether a special home-visit program (based on the Tidal Model) can improve your mood and mental health, and reduce how often you need to go to the hospital. It is for people with severe COPD who live in the city center of Kilis.
Kilis, KilisAges Up to 100 years - NCT06754319Recruiting
Gut bacteria and brain connection in child OCD
This study looks at how the bacteria in your gut might affect OCD in children and teens. It tests a possible link between your gut, brain, and OCD symptoms.
Shanghai, Shanghai MunicipalityAges 7–17 - NCT06738784Recruiting
Task analysis system for aging psychiatric patients living at home
This trial tests a system to help care teams better support adults over 40 with aging psychiatric disorders who live independently. The goal is to improve decisions about what kind of help and housing you need.
Bourdeaux, GirondeAges 40–65 - NCT06717165Recruiting
Brain stimulation with talk therapy for OCD
This study tests if adding a gentle brain stimulation technique (tACS) to cognitive behavioral therapy (CBT) can help reduce OCD symptoms more than CBT alone. It is for adults with OCD who have not completed a full course of CBT before.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT06736522Recruiting
Youth leadership and mindfulness program for high school students
This study tests a program designed to build leadership skills, engagement, and mindfulness in high school students. If you're a teen in certain Massachusetts or Illinois schools, this program may help you grow personally and socially.
Chicago, IllinoisAges 14 years+ - NCT06724965Recruiting
Trauma treatment and PrEP support for transgender and nonbinary adults
This study combines a proven trauma treatment (STAIR) with peer-led PrEP navigation to help transgender and nonbinary people cope with stress and stay HIV-free. It aims to improve mental health and increase PrEP use.
Los Angeles, CaliforniaAges 18 years+ - NCT06711666Recruiting
Maternal mental health and baby's brain in heart disease
This study looks at how a mother's mental health during pregnancy may affect the brain development of babies with a serious heart condition called critical cyanotic congenital heart disease (CHD). It aims to understand this link to improve support for families.
MarseilleAges Up to 50 years - NCT06702722Recruiting
Therapy and HIV support for moms in Malawi
This study tests if combining problem-solving therapy with HIV care support can improve mental health and HIV outcomes for pregnant women living with HIV in Malawi who have elevated depressive symptoms.
LilongweAges 18 years+
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Common questions
- Are there clinical trials for mental health?
- Yes. Clin2 currently lists 700 recruiting mental health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.