Clinical trials
Migraine Disease clinical trials
Below are recruiting migraine disease clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06716489Recruiting
Exercise study for women with migraine
This study tests whether aerobic exercise can help reduce migraine symptoms and improve how your body senses and responds to pain. It is specifically for women aged 18–48 who have migraine headaches 3–8 days per month.
Ribeirão Preto, São PauloAges 18–48 - NCT07022496RecruitingPhase 4
Can oral caffeine help with acute migraine attacks?
This trial tests whether taking caffeine by mouth can reduce the severity of a migraine attack when it happens. It may offer a simple, at-home option for people with different types of migraine.
CairoAges 18–60 - NCT06938178Recruiting
EEG markers of mindfulness for migraines
This trial uses EEG (brain wave) tests to see if mindfulness therapy, added to your regular treatment, helps people with frequent migraines (8–14 headache days per month). You will have brain scans before and after mindfulness sessions to look for changes that show it's working.
MilanAges Any age - NCT07451769Recruiting
Testing a new drug target for migraine relief
This trial tests a substance that activates adrenomedullin receptors, which may be a new way to treat migraines. It may help people who have migraines without aura and aren't on preventive migraine medications.
Glostrup MunicipalityAges 18–65 - NCT07233941Recruiting
Cognitive and psychological study in migraine patients
This study looks at thinking abilities and psychological factors in people with migraines. It aims to understand how migraine affects memory, attention, and emotions.
MilanAges 18–65 - NCT07754266Recruiting
Headache, ear, and dizziness registry
This study collects information from people who have headaches, ear problems, dizziness, or sinus issues to better understand these symptoms and how they relate to migraine. Your participation may help improve future treatments and diagnosis.
North Kingstown, Rhode IslandAges 18 years+ - NCT07720765Recruiting
Using eye scans to study brain diseases
This trial uses a type of eye scan (OCT) to look at the retina in people with brain conditions like multiple sclerosis, Alzheimer's, Parkinson's, or migraines. It aims to see if these scans can help doctors learn more about the disease and monitor it over time.
Milan, MilanoAges 18 years+ - NCT06426316Recruiting
Immune cells and migraines study
This study looks at how certain immune cells and inflammatory chemicals relate to migraines. If you have migraines or an autoimmune condition (like lupus, rheumatoid arthritis, or Crohn's disease), you may be able to participate. The goal is to understand what causes migraines.
Clermont-Ferrand, AURAAges 18–50 - NCT04063540RecruitingPhase 2
Amiloride to prevent migraine aura episodes
This study tests whether amiloride can reduce how often migraine aura happens. It’s a proof-of-concept early study, meaning the main goal is to see if the approach seems to work and is safe for people with frequent aura.
BronAges 18–80 - NCT07518069Recruiting
Understanding Genes and Biology in Menière's Disease
This research study investigates the genetic and biological factors that cause Menière's disease—a condition affecting the inner ear that causes dizziness, hearing loss, and ear fullness. By studying these factors, researchers hope to better understand why some patients experience different symptoms and potentially improve future treatments.
Milan, ItalyAges 18 years+ - NCT06537700Recruiting
Testing Botox for Chronic Migraine: Does Timing Matter?
This study tests how well Botox works for chronic migraine patients, depending on how long they've had the condition. If you have chronic migraines, haven't had Botox recently, and meet a few other conditions, you may be able to join.
AnconaAges 18–70 - NCT05582837RecruitingPhase 4
Using migraine medicines to treat Meniere’s disease symptoms
This Phase 4 study tests whether migraine-type medications can help people with active or frequent Meniere’s disease. If you have symptoms like inner-ear episodes, the trial may help find a better way to control them.
Orange, CaliforniaAges 25–85 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06810505RecruitingPhase 3
Oral atogepant for preventing migraines in teens
This trial tests an oral medication called atogepant to see if it can prevent migraines in teens aged 12–17. It aims to reduce how often migraines happen and track any side effects.
Huntsville, AlabamaAges 12–17 - NCT05125302RecruitingPhase 3
Ubrogepant for acute migraine relief in kids and teens
This study tests how safe ubrogepant is and whether it helps treat an individual migraine attack in children and teens. It focuses on measuring side effects and whether headaches improve 2 hours after taking the study medicine.
Huntsville, AlabamaAges 6–17 - NCT05711394RecruitingPhase 3
Atogepant for preventing episodic migraine in children
This study tests whether an oral medicine called atogepant can reduce migraine activity in children ages 6–17 and checks its side effects. It’s meant for kids with episodic migraine (not the more constant types) who may benefit from preventive treatment.
Huntsville, AlabamaAges 6–17 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+
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Common questions
- Are there clinical trials for migraine disease?
- Yes. Clin2 currently lists 17 recruiting migraine disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a migraine disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a migraine disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.