Clinical trials
Mild Cognitive Impairment clinical trials
Below are recruiting mild cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 410 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07560904Recruiting
Brain Stimulation to Improve Memory in Cognitive Decline
This study tests a non-invasive brain stimulation technique to help improve working memory (the ability to hold and use information briefly) in people with mild cognitive impairment related to Parkinson's disease or Lewy body disease. The stimulation targets deep brain structures without surgery.
BrnoAges 60–80 - NCT07553338RecruitingPhase 2
Leronlimab Safety and Brain Inflammation in Alzheimer's
This study tests whether a drug called leronlimab is safe and can reduce inflammation in the brains of people with mild-to-moderate Alzheimer's disease or memory problems. Researchers will use special brain scans to see if the drug affects inflammation.
New York, New YorkAges 50 years+ - NCT07516119Recruiting
Predicting Alzheimer's Risk Before Memory Loss Occurs
This study identifies people at high risk for Alzheimer's disease before symptoms develop, using genetics and digital tools to track brain health over time. If you qualify, you'll help researchers understand who will develop cognitive decline and potentially enable earlier interventions.
San Diego, CaliforniaAges 55 years+ - NCT07499570Recruiting
Talk therapy using AI for older adults with memory issues
This study tests an AI-powered talk therapy for older adults with mild memory problems who live at home. It aims to reduce challenging behaviors like agitation, anxiety, or depression by delivering personalized support through a computer or tablet.
Indianapolis, IndianaAges 65 years+ - NCT07485725Recruiting
Digital tools study for health decisions
This study tests if digital tools can help older adults make better healthcare decisions. You’ll use a website to search for health information and share your thoughts in interviews.
Tallahassee, FloridaAges 60 years+ - NCT07454824Recruiting
Aligning medications with what matters most: patient portal trial
This study tests whether a patient portal tool can help older adults with memory problems and their care partners adjust medications to better match their personal goals and values. It is for people who are 65 or older, have mild cognitive impairment or dementia, are taking a medication that may not be ideal for their age, and use the patient portal.
Baltimore, MarylandAges 65 years+ - NCT07441122Recruiting
Brain game for focus: Using brain-computer tech in older adults
This study tests if a brain-computer interface can help older adults improve attention. You'll use a computer that reads your brain signals and gives feedback to train your focus.
Austin, TexasAges 18–90 - NCT05771844Recruiting
Home sleep treatment for older adults with memory changes
This study tests whether a home sleep therapy program can improve symptoms in older adults who have amnestic mild cognitive impairment (MCI) or help compare to people without MCI. It may be useful if your main issue is memory or thinking changes and you also have sleep problems.
Winston-Salem, North CarolinaAges 40–85 - NCT06850597RecruitingPhase 2
Testing dimethyl fumarate for early Alzheimer's disease
This study tests a drug called dimethyl fumarate to see if it can help people with early Alzheimer's disease. It may slow down memory loss and thinking problems.
Lodz, Łódź VoivodeshipAges 55–90 - NCT04956549Recruiting
Exercise program for early memory loss in African Americans
This study tests whether a structured exercise program can lower Alzheimer’s risk in older African American adults who have mild cognitive impairment (MCI). You’ll be placed by chance into an exercise group or a comparison group and attend group sessions for about a year.
Baton Rouge, LouisianaAges 60 years+ - NCT07272811Recruiting
Computer memory testing for early Alzheimer's signs
This study uses a computer-based platform to test memory and thinking in healthy adults and in people with mild memory concerns (called aMCI). The goal is to better understand how memory changes with age and to spot early signs of Alzheimer's disease.
Milan, ItalyAges 55–80 - NCT07238049Enrolling by invitation
Real-world dementia outcomes: an observational study
This study follows people with memory or thinking problems over time to learn more about how these conditions progress. It's an observational study, meaning no new treatments are tested—just information is collected from your regular care.
BangorAges 45 years+ - NCT07220668RecruitingPhase 1/Phase 2
Safety check for older adults in senior living
This trial tests a new program called Sense4Safety to help prevent falls and keep seniors living independently. It uses a simple physical test and a memory screening to see if you're eligible.
Philadelphia, PennsylvaniaAges 65 years+ - NCT07166224Recruiting
Home treatments for gum disease in older adults with memory issues
This trial tests two simple ways to improve gum health at home: using a special light-activated antibacterial rinse or using a powered toothbrush. It's for older adults who have gum disease and mild memory problems, and aims to see if these easy routines can help keep gums healthier.
Karlskrona, Blekinge CountyAges 60 years+ - NCT07154394Recruiting
Heart amyloid and function in Alzheimer's disease
This study examines whether amyloid plaques in the heart affect heart function in people with Alzheimer's disease. It uses brain amyloid PET and MRI scans to explore a potential link.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT07120347Recruiting
Remote sensors to study daily activities in older adults with mild memory loss
This study uses remote sensors (like motion detectors) to see how older adults with mild memory or thinking problems go about their daily lives. It may help researchers learn how to better support people with early dementia.
Columbia, MissouriAges 50 years+ - NCT07089303Recruiting
Alzheimer's brain imaging study (AD-MINER)
This study uses advanced brain imaging to learn more about Alzheimer's disease. It looks at people with normal memory, mild memory problems, or Alzheimer's dementia to find better ways to diagnose and track the disease.
Beijing, Beijing MunicipalityAges 55–90 - NCT07083089Recruiting
Hearing and thinking in early Alzheimer's and Parkinson's
This trial studies how hearing relates to early memory and movement problems in Alzheimer's and Parkinson's diseases. It may help find new ways to detect and track these conditions.
MontpellierAges 50–85 - NCT06983119Recruiting
Finding early signs of memory loss in Pavia
This study looks for early thinking and memory changes in people 50 and older who haven't been diagnosed with cognitive decline. You'll complete a quick assessment to see if further checkups might help.
Pavia, PaviaAges 18 years+ - NCT07058688RecruitingPhase 2
Testing a new drug for Alzheimer's (NTRX-07)
This study tests an experimental drug for Alzheimer's called NTRX-07. It aims to see if it can slow memory decline for people with mild to moderate Alzheimer's.
BrnoAges 65–80 - NCT07012993RecruitingPhase 2
Very low dose PET brain scan study
This study tests whether using a very low dose of radiation for a brain PET scan can still give clear images. If you are eligible, you will get a type of radioactive tracer that helps show amyloid plaques in the brain, often used in Alzheimer's research.
Englewood, New JerseyAges 18–120 - NCT06429124Recruiting
Time-restricted eating for mild cognitive impairment
This trial tests whether a time-restricted eating schedule (eating only during certain hours of the day) can help people with mild cognitive impairment (MCI) or early Alzheimer’s disease. It is a lifestyle study that can be done mostly from home with a computer or smartphone.
Phoenix, ArizonaAges 55–89 - NCT06982261Recruiting
Voice assistant program for older adults with mild memory concerns
This study tests a voice technology program to help older adults manage their health at home. If you have mild memory issues, live alone, and meet income guidelines, you might be eligible.
Atlanta, GeorgiaAges 55 years+ - NCT06962111Recruiting
Partner in Care Living Alone Plus study for early-stage dementia
This study tests a workshop to help people with early-stage memory problems who live alone. If you have mild dementia or mild cognitive impairment and can join Zoom sessions, you may be eligible.
Phoenix, ArizonaAges 60 years+
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Common questions
- Are there clinical trials for mild cognitive impairment?
- Yes. Clin2 currently lists 410 recruiting mild cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Amnestic Mild Cognitive Impairment
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
- Subjective Cognitive Impairment
- Post-Stroke Cognitive Impairment (PSCI)
- Vascular Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.