Clinical trials
Mild Cognitive Impairment clinical trials
Below are recruiting mild cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 410 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06935812Recruiting
Comparing hand exercises and VR for memory problems
This study compares three types of exercises (using both hands, finger movements, and virtual reality) in people with mild memory loss to see which helps thinking and memory best.
Famagusta, Eyalet/YerleşkeAges 50–75 - NCT06918704Recruiting
Digital brain health program for older adults
This study tests a digital program designed to help support thinking and memory in older adults. It may be a good fit if you are 60+ and generally healthy, even if you have some mild memory concerns.
San Francisco, CaliforniaAges 60–85 - NCT06916221Recruiting
Digital brain training in aging
This study tests whether a digital intervention can help older adults (60+) maintain or improve cognitive function. It is designed for healthy adults or those with mild cognitive impairment (MCI), and people who do not regularly play a musical instrument or have extensive music training.
San Francisco, CaliforniaAges 60–85 - NCT06869135Recruiting
Saliva testing for brain diseases
This trial is collecting saliva samples from people with Alzheimer's, Parkinson's, or other brain diseases to find new ways to diagnose them. It may help improve early detection.
Florence, FIAges 45 years+ - NCT05710549Recruiting
Brain study of autobiographical memory using brain stimulation
This study looks at how the brain supports remembering your own past experiences. It tests brain mechanisms using brain scanning (MRI) and noninvasive brain stimulation to see how these memory processes work.
Geneva, Canton of GenevaAges 18–85 - NCT06783283Recruiting
Brain stimulation to improve memory in mild cognitive impairment
This trial tests whether a gentle electrical brain stimulation technique called tACS can improve working memory in people with mild cognitive impairment (MCI). If you have MCI due to early Alzheimer's, this study may help find new ways to boost memory.
Toronto, OntarioAges 60 years+ - NCT05697588Recruiting
Study blood and brain markers from mild memory loss to dementia
This study looks for “biomarkers” (measurable signs from blood and brain tests) that may help predict who with mild cognitive impairment (MCI) could later develop dementia. Results may help doctors spot risk earlier and better plan care.
Beijing, Beijing MunicipalityAges 50–85 - NCT06761066Enrolling by invitation
Testing NVP-NK4146 for mild cognitive impairment due to Alzheimer's
This study tests a new medicine, NVP-NK4146, for people with mild cognitive impairment (MCI) due to Alzheimer's disease. The goal is to see if it can help slow down memory and thinking problems.
SeoulAges 60 years+ - NCT06254469RecruitingPhase 3
PET scan study for memory decline with head injury or Alzheimer's risk
This trial uses a special PET scan tracer to see if it can predict who will get worse over time. It is for people with mild memory or thinking problems that may be linked to past head injuries or early Alzheimer's disease.
Evanston, IllinoisAges 45 years+ - NCT06741553Recruiting
Studying lecanemab for early Alzheimer's disease
This study looks at how well lecanemab works for people with early Alzheimer's disease. It aims to see if the drug can help slow down memory and thinking problems.
Hangzhou, ZhejiangAges Up to 85 years - NCT06722976Enrolling by invitation
Digital health and exercise for staying independent longer
This trial tests a program that combines digital health tools with exercise to help older adults stay active and independent. It may be a good fit if you are 65 or older and can walk or move around without major difficulty.
Covilha, CovilhãAges 60 years+ - NCT06703541Recruiting
Alzheimer's disease research study with brain scans and spinal tap
This study at Duke University is looking for people aged 25 to 80 who may be at risk for Alzheimer's disease. It involves brain scans (MRI and PET) and a spinal tap to learn more about the disease and find better ways to detect and treat it early.
Durham, North CarolinaAges 25–80 - NCT06548191RecruitingPhase 1
Time-Restricted Eating for Alzheimer's Disease
This study tests whether a time-restricted eating schedule (eating all meals within a 10-hour window each day) can improve memory and thinking in people with early Alzheimer's disease or mild cognitive impairment. Healthy partners of people with memory problems can also join as a comparison group.
San Diego, CaliforniaAges 60 years+ - NCT06538311RecruitingEarly Phase 1
TMS treatment for early Alzheimer's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help people with early Alzheimer's disease or related memory problems. It's a safe, gentle way to stimulate brain cells using magnetic pulses.
Boston, MassachusettsAges 40–99 - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT06489548RecruitingPhase 2
Foralumab for Early Alzheimer's Disease
This study tests an experimental drug called Foralumab, which aims to calm overactive immune cells in the brain linked to Alzheimer's. It may help slow memory loss in people with early-stage Alzheimer's.
Boston, MassachusettsAges 60–85 - NCT06467539RecruitingPhase 2
New combination treatment for early Alzheimer's or memory loss
This trial tests a new combination treatment (DAOIB and an antioxidant) for people with early Alzheimer's or mild cognitive impairment. It aims to see if the treatment can help slow or improve memory and thinking problems.
Kaohsiung CityAges 50–90 - NCT03761381Recruiting
Eye scan study for mild Alzheimer’s and memory changes
This study uses detailed eye imaging (an eye scan) to look for signs related to probable Alzheimer’s disease and mild dementia. It may help researchers understand whether eye scans can reflect brain changes and improve detection.
Portland, OregonAges 55 years+ - NCT06453980Recruiting
Brain plasticity study in mild memory loss
This study looks at how the brain changes in people with mild memory problems. It uses brain scans and a gentle, non-invasive electrical stimulation to see if we can improve brain function.
Ann Arbor, MichiganAges 60 years+ - NCT06307574Recruiting
Smartphone study to help older adults manage blood pressure medication
This study tests a digital tool called bpMedManage to help adults aged 60 and older remember and manage their blood pressure medications. It's for people who have some memory or thinking challenges and use a smartphone.
Tucson, ArizonaAges 60 years+ - NCT06112860Recruiting
Over-the-counter hearing aids for memory loss study
This trial tests whether over-the-counter hearing aids can help people with mild memory loss (mild cognitive impairment or mild dementia) who also have hearing loss. You and a communication partner will participate together to see if improving hearing can also help with thinking and communication.
Evanston, IllinoisAges 60–90 - NCT06090578Recruiting
Brain health check for adults in primary care
This trial tests a new brain health assessment tool in primary care clinics. It may help your doctor better detect thinking or memory changes early.
Pasadena, CaliforniaAges 18 years+ - NCT06102486Recruiting
Speech in noise study for mild cognitive impairment
This study looks at how well people with mild cognitive impairment (MCI) understand speech in noisy settings. It aims to find better ways to diagnose and help people with thinking and memory concerns.
Lebanon, New HampshireAges 55–80 - NCT06072963RecruitingPhase 2
Combining insulin and semaglutide for memory in MCI with metabolic syndrome
This study tests if a combination of insulin and semaglutide (a diabetes drug) can improve memory and thinking in people with mild cognitive impairment (MCI) who also have metabolic syndrome (a cluster of health issues like large waist, high blood sugar, and high blood pressure). It aims to see if treating blood sugar problems helps protect the brain.
Ramat GanAges 60–90
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Common questions
- Are there clinical trials for mild cognitive impairment?
- Yes. Clin2 currently lists 410 recruiting mild cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Amnestic Mild Cognitive Impairment
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
- Subjective Cognitive Impairment
- Post-Stroke Cognitive Impairment (PSCI)
- Vascular Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.