Clinical trials
Mild Cognitive Impairment clinical trials
Below are recruiting mild cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 410 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06825403Recruiting
Olfactory training for mild cognitive impairment
This trial tests whether daily scent training can help improve memory and thinking in people with mild cognitive impairment (MCI), a condition that is more than normal aging but not dementia. You would smell different odors at home and track your progress.
New York, New YorkAges 55–89 - NCT05708001Recruiting
Testing brain stimulation to improve memory in mild impairment
This study tests whether a noninvasive brain stimulation method (tACS) can improve memory in people with mild cognitive impairment (MCI). A caregiver also helps with the stimulation during the study, and success is measured through study visits and memory-related evaluations.
GenevaAges 55–85 - NCT06809725Enrolling by invitation
Study of a headband device for cognitive health check
This study tests a new way to check cognitive (thinking and memory) health using a simple headband that measures electrical signals on your scalp. It is looking for people 65 to 90 years old, with or without memory concerns, and a family member or friend who can also take part.
Miami, FloridaAges 65–90 - NCT06799429Recruiting
Exercise program for people with memory challenges
This trial tests whether a structured exercise program can help people with mild to moderate memory or thinking problems. You'll work with a trainer to improve your fitness and brain health.
Columbia, South CarolinaAges 18 years+ - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80 - NCT06330844Recruiting
Stress & memory support for Black and Hispanic older adults
This research study tests a new program that combines help for stress caused by racism with memory training for people with mild cognitive impairment. It may help Black and Hispanic/Latine older adults find ways to cope and improve thinking skills.
Chicago, IllinoisAges 65 years+ - NCT06780917Recruiting
Online cognitive testing for older adults with depression or memory concerns
This study tests whether an online cognitive assessment platform (Creyos) is valid for older adults with major depression or mild cognitive impairment. Participants will complete brain games or puzzles to see how well the online tool measures thinking skills.
Toronto, OntarioAges 60 years+ - NCT06723015Enrolling by invitationPhase 2
Tau PET in anti-amyloid therapy for Alzheimer's
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
Rochester, MinnesotaAges 50–90 - NCT06687161Recruiting
Treating insomnia in mild memory problems
This study tests whether a non-invasive brain stimulation method (TMS) combined with cognitive training can improve sleep in older adults with mild memory issues. It may help if you have trouble falling or staying asleep and have early memory changes.
Boston, MassachusettsAges 60 years+ - NCT06682741Enrolling by invitation
Comparing exercise programs for brain health in women
This study tests whether different types of exercise training can improve thinking and memory in women. It may help find the best workout for keeping your mind sharp.
Poznan, PolandAges 50 years+ - NCT06669546Recruiting
Quiet sounds during deep sleep for memory in older adults
This study tests whether playing a soft, silent sound (or no sound) during deep sleep can improve memory, brain activity, and blood markers. It is for older adults (60-85) who have mild memory issues but are otherwise healthy.
BernAges 60–85 - NCT06670807Recruiting
Probiotic supplement for mild memory loss
This study tests whether a probiotic (a supplement with helpful bacteria) can help slow down memory and thinking problems in people with mild cognitive impairment (MCI). It is for adults aged 60–85 who have noticed their memory getting worse over time but can still handle daily activities.
Madrid, MadridAges 65–85 - NCT06664229Recruiting
Dementia and fall prevention program for older adults
This study tests a pressure sensor-based program to help prevent dementia and falls in older adults. If you are 65 or older, can walk independently, and have no dementia or other conditions that affect thinking, you may be able to join.
Seoul, SeoulAges 65 years+ - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT06618807Recruiting
Infrared light for memory loss in mild cognitive impairment
This study tests whether shining a gentle infrared light on the head can help people with mild memory loss (MCI) improve their thinking and memory. It is designed for those who have mild cognitive impairment due to early Alzheimer's disease.
Toronto, OntarioAges 50 years+ - NCT06601933RecruitingPhase 2
Computer thinking exercises for memory concerns in older adults
This study tests whether a computer-based thinking exercise program can improve memory and brain function in older adults with mild memory concerns. If you have age-related memory changes but not dementia, you may be able to join and get a free MRI scan.
Miami, FloridaAges 55–89 - NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Atlantis, FloridaAges 60–90 - NCT06584110Recruiting
Buddy-up exercise program for dementia and caregiver
This study tests a buddy-up program where a person with mild to early moderate dementia and their family caregiver do physical activities together using video calls. It aims to see if exercising together helps both their health and well-being.
Hong KongAges 18 years+ - NCT06484244Recruiting
Walking and balance in memory loss
This study looks at how older adults with mild cognitive impairment or Alzheimer's disease adapt their walking. It aims to understand walking and balance to help people stay mobile and safe longer.
Atlanta, GeorgiaAges 50–90 - NCT06448403Recruiting
Alzheimer's assessment study with brain scans
This study uses brain scans (MRI and EEG) to better understand Alzheimer's disease. It compares people with MCI or Alzheimer's to healthy volunteers to see how the disease affects the brain.
Trondheim, TrønderlagAges 65 years+ - NCT05149742Recruiting
Study of hearing loss and thinking skills in midlife adults
This study looks at how severe hearing loss affects thinking and memory in adults aged 45–64. Researchers will compare people with significant hearing loss to people with normal hearing who are similar in age, sex, and education.
ParisAges 45–64 - NCT06434168Enrolling by invitation
Yoga for brain health in heart failure
This study tests whether yoga can help improve memory and thinking for people with heart failure who also have mild memory problems. It aims to see if a gentle yoga program can support both heart and brain health.
Auburn, AlabamaAges 55–70 - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06403345Recruiting
Green activity program for memory challenges
This study tests a green activity program for people with memory challenges. You and a friend or family member will take part in outdoor activities to see if they help with thinking and well-being.
Bloomington, IndianaAges 45 years+
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Common questions
- Are there clinical trials for mild cognitive impairment?
- Yes. Clin2 currently lists 410 recruiting mild cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Amnestic Mild Cognitive Impairment
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
- Subjective Cognitive Impairment
- Post-Stroke Cognitive Impairment (PSCI)
- Vascular Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.