Clinical trials
Multimodal Analgesia clinical trials
Below are recruiting multimodal analgesia clinical trials, each written for real people, not researchers. We’re tracking 28 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06507345Recruiting
Non-opioid pain relief after breast surgery
This trial tests whether non-opioid pain medicines can effectively control pain after mastectomy or lumpectomy, allowing you to go home the same day without needing strong opioids.
Montreal, QuebecAges 18 years+ - NCT07423650RecruitingPhase 4
Continuous Nefopam infusion after pancreas surgery
This trial tests if giving a steady dose of a painkiller called nefopam through an IV can help manage pain after a Whipple procedure (pancreatoduodenectomy). It aims to see if this approach reduces the need for other pain medications and improves recovery.
Cluj-Napoca, ClujAges 18–80 - NCT05597683Recruiting
Nerve block for pain after major abdominal cancer surgery
This trial studies whether a targeted nerve block (called a quadratus lumborum block) can improve pain control after cytoreductive surgery and heat-based chemotherapy put into the abdomen (CRS and HIPEC). It may help some people use less rescue pain medicine and feel more comfortable during recovery.
SeoulAges 19 years+ - NCT06446830Recruiting
Vitamin B complex for pain relief after cesarean in ICU
This trial tests whether adding vitamin B complex to standard pain medicine can improve pain control after a cesarean section in critically ill women. It aims to find a safer, effective way to manage pain without relying too much on strong opioids.
Cairo, EgyptAges Any age - NCT07427043RecruitingPhase 3
Opioid-free pain plan for robotic prostate surgery
This trial tests a pain management strategy that avoids opioids during and after robotic prostate surgery. It aims to reduce opioid use and side effects while keeping you comfortable.
Boston, MassachusettsAges 45 years+ - NCT07709975Recruiting
Pain relief and early movement for older ICU patients
This study tests different ways to manage pain and help older patients get moving again sooner after major surgery. If you are 65 or older and in the ICU, this trial may help you recover more comfortably and quickly.
Istanbul, IstanbulAges 65 years+ - NCT07051109Recruiting
Dual-chamber pain pump for recovery after weight-loss surgery
This trial tests a dual-chamber patient-controlled pain pump after weight-loss surgery. It may help women have better pain relief and recovery.
Seongnam-si, Gyunggi-doAges 19–65 - NCT06936995Recruiting
Comparing pain relief methods for ACL surgery recovery
This trial tests two ways to manage pain after ACL reconstruction: a combination of medications (multimodal analgesia) versus a nerve block in the thigh (femoral block). The goal is to see which approach provides better pain control and recovery.
AnkaraAges 18–65 - NCT06861387Recruiting
Cryo nerve block for lung surgery pain
This trial tests a freezing technique to numb nerves around the lungs during minimally invasive lung surgery. It may help reduce pain after surgery, so you need less pain medication.
Nieuwegein, UtrechtAges 18 years+ - NCT06819748Recruiting
Numbing medicine mix for less pain after gallbladder surgery
This trial tests a mixture of numbing medicines (ropivacaine cocktail) injected into the surgery area to reduce pain after gallbladder removal. It's for people having same-day laparoscopic surgery and aims to help you recover with less pain.
Chengdu, SichuanAges 18–70 - NCT07331441Recruiting
Nerve block for pain relief after major upper abdominal surgery
This trial tests a nerve block given near the ribs to see if it reduces pain after surgeries like gastric, liver, gallbladder, or pancreatic surgery. It may help you need less pain medicine after the operation.
ShanghaiAges 18–85 - NCT07458360Recruiting
Front block for better recovery after hip replacement
This study tests if a special nerve block called the front block (pericapsular nerve group block) improves recovery after hip replacement surgery. You may be eligible if you are having hip replacement under spinal anesthesia and do not have certain health issues.
KonyaAges 18 years+ - NCT06201676RecruitingPhase 4
Low-dose short-term ketorolac to cut opioid use after bone surgery
This study tests whether giving a low dose of a non-steroidal anti-inflammatory drug (NSAID) called ketorolac for a short time after orthopedic surgery can reduce the need for strong painkillers like opioids. It is for people who have broken bones that need surgery with metal plates, screws, or rods.
Boston, MassachusettsAges 18–70 - NCT07295184Recruiting
Rebound pain and confusion after hip surgery
This study looks at a way to reduce confusion after hip surgery. If you are having planned hip surgery and get a nerve block for pain, researchers will check if rebound pain affects your recovery in the hospital.
Konya, KaratayAges 18–80 - NCT07417462Recruiting
Pain relief after heart surgery to help you recover faster
This trial tests a combination of pain medicines given during cardiac surgery to reduce pain and speed up recovery. It may help patients who are having a first-time bypass surgery through a standard breastbone incision.
AsyutAges 40–60 - NCT06379425RecruitingPhase 4
Can pain meds without opioids help you pee sooner after surgery?
This study looks at whether giving a mix of pain medicines (without opioids) before surgery can help you recover faster and avoid needing a catheter after a vaginal repair or sling procedure. It enrolls women having minor gynecologic surgery at the South Shore Surgery Center in New York.
Bay Shore, New YorkAges Any age - NCT06563349RecruitingPhase 4
Magnesium study for kids having appendix surgery
This trial tests if magnesium sulfate can help children recover better after laparoscopic appendix removal. It aims to see if it reduces pain or other problems during and after surgery.
WarsawAges 1.5 years–18 years - NCT07291388Recruiting
Retrolaminar block for lumbar fusion with multimodal pain control
This study tests whether adding a retrolaminar block (a type of back injection) to standard pain medicines helps reduce pain after lumbar spine fusion surgery. It may help you recover with less need for strong painkillers.
Santiago, Santiago MetropolitanAges 18–75 - NCT06887153Recruiting
Pain medicine use after major surgery
This study looks at how different pain medicines are used together after major surgery and how well they control pain. It may help improve pain relief for people having planned bone, belly, or chest surgeries.
KampalaAges 18 years+ - NCT07070050RecruitingPhase 4
NSAIDs after laparoscopic surgery: continuous or bolus?
This study compares giving NSAID pain relievers continuously through an IV versus as single doses (bolus) after laparoscopic surgery to find which method provides better pain relief with fewer side effects.
Moscow, Moscow OblastAges 18 years+ - NCT07072286Recruiting
Regional anesthesia for pelvic fracture pain relief
This study tests whether regional anesthesia techniques, which numb the area around your pelvic fracture, can better manage your pain while you wait for surgery. It aims to see if these methods improve pain relief and reduce the need for other pain medicines.
TurinAges 18 years+ - NCT07226700RecruitingPhase 3
Suzetrigine for pain after hip replacement surgery
This study tests an investigational pain medicine called suzetrigine to see how well it controls pain after total hip replacement surgery. It is for adults 18–80 who are having a first-time hip replacement and can receive spinal anesthesia.
New York, New YorkAges 18–80 - NCT07315308Recruiting
Nerve block before heart surgery and painkiller use
This study tests whether a numbing injection in the chest before heart surgery can reduce the amount of pain medicine needed during the operation. It may help you manage pain better and recover more comfortably.
Gaziantep, SahinbeyAges 18–65 - NCT07455565Recruiting
Pain monitoring with ANI after lumbar spine surgery
This study tests a new way to monitor pain after lower back surgery using a device called ANI, which tracks your body's response to pain. The goal is to see if this method helps doctors give you better pain relief.
Antalya, AntalyaAges 18–65
Hear when a new Multimodal Analgesia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for multimodal analgesia?
- Yes. Clin2 currently lists 28 recruiting multimodal analgesia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multimodal analgesia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multimodal analgesia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.