Clinical trials
Sedation and Analgesia clinical trials
Below are recruiting sedation and analgesia clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05893030Recruiting
Monitoring pain and sleep medicines to prevent complications after surgery
This study looks at whether closely monitoring opioid and sleep medicines during and after surgery can lower organ problems and death in older adults at high risk. If you qualify, your team will track how these medicines are given to help keep you safer in the postoperative period.
AmiensAges 75 years+ - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT07657897Recruiting
Anesthesia effects on inflammation in liver cancer treatment
This study looks at how different types of anesthesia or sedation affect inflammation in people with early-stage liver cancer who are having a procedure called radiofrequency ablation (RFA). RFA uses heat to destroy small tumors, and researchers want to see if the choice of anesthesia influences the body's immune response, which might help improve recovery.
Cluj-Napoca, ClujAges 18–80 - NCT07211828Recruiting
Brain activity and pain signals during anesthesia study
This study looks at how opioids and sedatives affect brain activity and pain signals in patients getting anesthesia for an ERCP procedure.
MiaoliAges 18 years+ - NCT07146698Recruiting
No sedation vs. daily sedation breaks for COPD patients on a ventilator
This trial compares not using sedation at all versus daily breaks in sedation for people with COPD who are on a breathing machine (ventilator) in the intensive care unit. It aims to see if one approach leads to better outcomes, such as shorter time on the ventilator.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07495826Recruiting
Predicting behavior in kids during sedation
This study looks at children aged 1 to 17 who get sedation or anxiety medicine for a procedure in the emergency department or dental clinic. Researchers want to understand what predicts how children behave during and after sedation.
London, OntarioAges 1–17 - NCT06449430Recruiting
Turning a Breech Baby: Sleep vs. Spinal Numbing
This trial compares two ways to help turn a breech baby to a head-down position: one uses a light sleep medicine (propofol), the other uses numbing medicine in the spine (bupivacaine). The goal is to make the turning attempt more comfortable and successful.
Murcia, MurciaAges 18 years+ - NCT07443254RecruitingPhase 1/Phase 2
IR-led deep sedation study for image-guided procedures
This study tests if a radiologist can safely give deep sedation medicine (ketamine) for certain procedures instead of general anesthesia. It might help you avoid general anesthesia while still being comfortable.
Charleston, West VirginiaAges 18 years+ - NCT06769308Recruiting
Brain wave guided sedation in ICU patients
This study tests a new way to give pain and sedation medicines in the ICU. It uses a special brain wave monitor (EEG) to help doctors adjust your medicines more precisely, aiming to keep you comfortable and safe.
Ferrara, ItalyAges 18–90 - NCT05160987Recruiting
Sedation choice for ICU patients on breathing machines
This study compares two sedation medicines—remimazolam vs midazolam—for very sick ICU patients who are on a breathing machine. It looks at whether one sedative works better or is safer for keeping patients comfortable while they’re critically ill.
Guangzhou, GuangdongAges 18–80 - NCT06867289Recruiting
Nasal sedation study for children during brain MRI
This trial tests a nasal spray sedative (dexmedetomidine) to help children stay calm during a brain MRI. It may be an option if your child struggles with the scan due to age or cooperation issues.
MetzAges 1–18 - NCT07413848Recruiting
Pain response monitor during urology procedures
This study tests a device that measures pain signals during urology procedures like cystoscopy or prostate biopsy. It may help doctors give you the right amount of sedation.
Ankara, AltındağAges 18 years+ - NCT07314450Recruiting
Pain and sedation for fracture and dislocation treatment in the ER
This study tests how well pain and sedation medicines work in the emergency department when treating adults with certain broken bones or dislocated joints that need to be set or casted. It aims to see which approach is safest and most comfortable for patients.
Holbæk, Region SjællandAges 18 years+ - NCT07669012RecruitingPhase 1
Sedation comparison for child heart hole repair
This study compares two sedation combinations (ketamine-propofol vs. dexmedetomidine-propofol) in children having a heart catheter procedure to close a simple hole or opening. The goal is to see which combination provides safer, more comfortable sedation.
CairoAges 2–12 - NCT07677982Recruiting
Understanding consent and sedation needs for endobronchial ultrasound
This study looks at how well patients understand the consent process and how much sedative medication they need during an endobronchial ultrasound (a scope test to look at the lungs and lymph nodes). It aims to improve care for people undergoing this procedure.
Bursa, BursaAges 18 years+ - NCT06464263Recruiting
Dexmedetomidine vs. midazolam-fentanyl for sedation
This trial compares two sedation and pain relief medicine combinations (dexmedetomidine vs. midazolam-fentanyl) to see which works better for people having planned heart valve surgery.
CairoAges 21–50 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT07182851Recruiting
Pain in patients on breathing machines in the ICU
This study looks at pain in patients who are on a breathing machine (ventilator) in the intensive care unit. It aims to understand pain better so doctors can help manage it more effectively.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07423195Recruiting
Cannabis use during wisdom tooth removal study
This study looks at how cannabis use affects pain and recovery after wisdom tooth surgery. If you are 16 or older and need a lower wisdom tooth removed, you may be able to join.
Ann Arbor, MichiganAges 16–99
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Common questions
- Are there clinical trials for sedation and analgesia?
- Yes. Clin2 currently lists 20 recruiting sedation and analgesia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sedation and analgesia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sedation and analgesia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.