Combined pain medicine for brain tumor surgery
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This study tests a combination of pain medicines given before, during, and after surgery to see if they can better control pain and reduce the need for strong opioids. It is for adults having planned surgery to remove a tumor from the upper part of the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are in generally good or fair health (ASA I to III).
- You are scheduled for planned (elective) surgery to remove a tumor in the upper part of the brain (supratentorial).
- You do not have a skin infection where the surgeon will make the cut.
- You have not had brain surgery before.
- You are not allergic to the medicines used in the study (opioids or local anesthetics).
- You have not had recent confusion, memory problems, or trouble staying awake.
- You are able to communicate and follow instructions.
- You do not have ongoing pain in the surgical area before surgery.
- You do not have severe liver or kidney problems.
- You do not have a very slow heart rate (below 40 bpm) or certain heart rhythm problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new pain management plan for people having brain tumor surgery. The goal is to see if combining different pain medicines before, during, and after surgery can reduce pain and improve recovery.
This study tests adding a sedative (dexmedetomidine) to the usual numbing medicine (bupivacaine) for a scalp block before brain surgery. The goal is to see if this combination reduces pain after surgery better than the numbing medicine alone.
This trial compares two medicines, ketamine and dexmedetomidine, added to a scalp nerve block during brain tumor removal surgery. The goal is to see which provides better pain control and recovery after surgery.
This trial tests if adding dexmedetomidine to a standard numbing medicine (bupivacaine) provides better pain control after heart surgery. The medicine is given as a nerve block before surgery to help with recovery and possibly allow faster breathing tube removal.
This trial tests whether numbing the scalp with a nerve block before brain surgery can reduce pain after the operation, keep your heart rate and blood pressure stable, and lower your body's stress response to surgery.
This trial tests if a calming medicine (dexmedetomidine) given during and after brain tumor surgery can help prevent confusion or delirium afterwards.
Hear when a new Postoperative Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.