Clinical trials
Multiple sclerosis clinical trials
A condition in which the immune system attacks the protective covering of nerves. We’re tracking 443 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05433103Recruiting
Blood flow restriction training for veterans with multiple sclerosis
This trial tests whether a special exercise method that briefly limits blood flow to the legs can improve strength and walking ability in people with multiple sclerosis (MS). If you have walking limitations, it may help you build fitness with less heavy resistance training—but you must be able to safely use a pressure cuff during testing.
Aurora, ColoradoAges 18–75 - NCT05482906Recruiting
Smartphone and MRI study for people with multiple sclerosis
This study looks at how information from a brain/spinal MRI and a smartphone relates to walking and daily function in people with multiple sclerosis (MS). It may help researchers understand what signals predict changes over time.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT05493514Recruiting
Robotic training program for walking and balance
This trial studies whether a robotic training system (called G-EO) can help people with neurological conditions improve walking and balance. It may help by testing which factors predict who benefits most, and it requires regular training sessions.
MilanAges 18 years+ - NCT05620940RecruitingPhase 1
IV drug safety and absorption study in healthy men
This Phase 1 study tests two experimental medicines given by IV to healthy men. It checks safety and how the body absorbs and processes the drugs (their “pharmacokinetic” profile).
Herston, QueenslandAges 18–55 - NCT05634967Recruiting
Kesimpta pregnancy registry for pregnant people with MS
This registry collects information about pregnancy outcomes in people with multiple sclerosis (MS) who have taken Kesimpta (ofatumumab) during pregnancy or shortly before it. It may help doctors better understand safety and developmental outcomes for babies.
La Jolla, CaliforniaAges 18–100 - NCT05644522Recruiting
At-home brace study for leg support and walking
This study tests an at-home wearable activity monitor and brace-related walking support for people who already use a knee-ankle-foot brace. It may help researchers understand how brace use and day-to-day movement relate to walking ability.
Chicago, IllinoisAges 18–89 - NCT05772637Recruiting
Testing bladder feeling in people with multiple sclerosis
This study checks how your bladder “sensation” works using bladder testing (including urodynamic testing) to better understand MS-related bladder problems. It may help researchers match bladder symptoms to what’s happening inside the bladder.
Paris, Choisir Une RégionAges 18–99 - NCT05776511Recruiting
Eye Movement Test for White Matter Brain Changes
This study tests whether a special eye-tracking camera can help diagnose the cause of white matter hypersignals—unusual bright spots seen on brain MRI. Researchers want to see if eye movements can reveal clues about what's causing these brain changes.
NiceAges 18 years+ - NCT05787795Recruiting
Studying early risk signs for multiple sclerosis
This study looks at people who are at higher risk for multiple sclerosis (MS), to better understand early changes before MS is diagnosed. It may help doctors identify who is more likely to develop MS and how to monitor them sooner.
North Haven, ConnecticutAges 18 years+ - NCT05819008Recruiting
Online brain testing for people with neurological conditions
This trial studies how well a remote, online memory and thinking assessment works for people with neurological disorders or injuries. You may be invited if you can do the computer-based testing and speak Swedish.
UmeåAges 18 years+ - NCT05901259Recruiting
Tracking routine outcomes using a mobility suit database
This trial sets up a database to follow routine health and mobility outcomes over time. You may be included if you have certain neurological conditions and can safely use the EXOPULSE suit.
Bergshamra, Stockholm CountyAges 2 years+ - NCT05934188Recruiting
Study how gut signals relate to brain aging and diseases
This study looks at how the gut may influence the brain in normal aging and conditions like Alzheimer’s, Parkinson’s, and multiple sclerosis. It may help researchers understand new ways to measure or treat these brain changes over time.
Venice-Lido, VeniceAges 20–90 - NCT05999604RecruitingPhase 3
Yearly vs every-6-month infusions for active MS
This study compares receiving ocrelizumab infusions every 6 months versus once a year for people with active MS who have already been on treatment for 2 years. The goal is to see if yearly infusions work just as well to keep the disease quiet on MRI scans.
CréteilAges 18 years+ - NCT06062693Recruiting
Home Hand Training with Sensors for Better Dexterity
This study tests a new home-based hand training system using sensors to help improve hand movement and dexterity in people with Parkinson's, multiple sclerosis, or stroke. It also includes healthy volunteers for comparison.
LucerneAges 18–99 - NCT06072703Recruiting
Brain stimulation for bladder control in MS
This study tests whether a type of brain stimulation can improve bladder control in women with multiple sclerosis. If you have bladder symptoms like urgency or frequent urination, this trial may help find new ways to manage them.
Houston, TexasAges 18 years+ - NCT06112639Recruiting
Dance-based rehab for chronic brain conditions
This trial tests a dance exercise program for people with multiple sclerosis or early memory loss. It aims to see if dancing can help physical and mental function safely at home.
BresciaAges 18–85 - NCT06195800Recruiting
Biomarkers after stem cell transplant for neurological diseases
This trial looks at biomarkers (biological signs in your blood) in people with immune-mediated neurological diseases. It compares those getting a stem cell transplant to those on high-efficacy MS treatments to understand how these therapies work.
Sheffield, EnglandAges 16 years+ - NCT06218927Recruiting
Stem cell transplant and bladder function in MS
This study looks at whether a stem cell transplant (AHSCT) can improve bladder problems and quality of life in people with multiple sclerosis (MS). It compares people getting this treatment with those on standard MS therapy.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT06219304Recruiting
High intensity training for multiple sclerosis
This trial tests whether high intensity exercise can improve both movement and thinking in people with multiple sclerosis. It might help if you can walk but need some support for balance.
Milan, MIAges 18 years+ - NCT06267781Recruiting
MS progression and immune cells after bone marrow transplant and other therapies
This study looks at how well different treatments, including bone marrow transplant, alemtuzumab, ocrelizumab, and ofatumumab, work for people with relapsing-remitting MS who have active disease. It will help doctors understand which therapy might slow disease progression best.
MilanAges 18 years+ - NCT06280755Recruiting
AI-assisted MS care study
This study looks at how artificial intelligence (AI) can help doctors care for people with multiple sclerosis (MS) and other similar conditions. It uses existing medical data to see if AI can improve treatment decisions.
Prague, Praha 2Ages 18 years+ - NCT06329453Recruiting
Gut immunity and brain health study
This study looks at how your gut's immune system relates to brain and nerve diseases. Researchers will collect samples during a colonoscopy to better understand connections between gut health and neurologic conditions like multiple sclerosis or Parkinson's disease.
North Haven, ConnecticutAges 18–99 - NCT06343558Recruiting
Gait and balance study for rare neurological diseases
This study looks at how people with rare or common neurological diseases walk and keep their balance. You will be asked to do simple walking and standing tasks to help doctors understand these problems better.
Milan, MilanAges 18–80 - NCT06369766Recruiting
Eye scans to find retinal markers in neuroinflammatory diseases
This study uses advanced eye scans (OCT and retinal vessel imaging) to look for patterns in the retina that might be different in people with Multiple Sclerosis and other neuroinflammatory diseases. The goal is to find markers that could help doctors better understand and monitor these conditions.
BaselAges 18 years+
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Common questions
- Are there clinical trials for multiple sclerosis?
- Yes. Clin2 currently lists 443 recruiting multiple sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Multiple Sclerosis, Relapsing-Remitting
- Multiple Sclerosis (MS) - Relapsing-remitting
- Multiple Sclerosis, Secondary Progressive
- Relapsing Multiple Sclerosis
- Multiple Sclerosis, Primary Progressive
- Progressive Multiple Sclerosis
- Multiple Sclerosis (MS) Primary Progressive
- Multiple Sclerosis (MS) Secondary Progressive
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.