Clinical trials
Multiple sclerosis clinical trials
A condition in which the immune system attacks the protective covering of nerves. We’re tracking 443 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04699747RecruitingPhase 1
MRI and PET scan study for multiple sclerosis brain changes
This Phase 1 study tests a special tracer used during MRI and PET scans to look at brain changes in people with multiple sclerosis. It’s mainly aimed at improving how these scans can detect disease-related changes and confirming the tracer works safely.
Boston, MassachusettsAges 18–65 - NCT05010902Recruiting
Pregnancy and MS study for people 18 and older
This study follows people with multiple sclerosis (MS) or a related condition to learn how pregnancy affects MS. You may be asked to complete health questionnaires and get MRI scans, which can help researchers understand what changes during pregnancy.
BerlinAges 18–50 - NCT05227092Recruiting
MRI scan method test for early spinal lesions in MS
This trial tests a new 3D MRI scan technique to find small, focused spinal cord lesions earlier in people with multiple sclerosis or early MS signs. It may help doctors detect changes sooner, even if lesions are not clearly visible on the first scan.
BordeauxAges 18 years+ - NCT05539729RecruitingPhase 1
Testing vancomycin for newly diagnosed multiple sclerosis
This Phase 1 study tests whether the antibiotic vancomycin can be given safely to people with newly diagnosed multiple sclerosis (or related early stages). It mainly focuses on safety and side effects, and whether the approach is feasible for this group.
New York, New YorkAges 18–50 - NCT05811013Recruiting
Static magnetic brain stimulation for progressive multiple sclerosis
This trial studies whether a noninvasive brain stimulation approach using a static magnetic field can help people with progressive multiple sclerosis. It aims to improve progressive nerve function while keeping other treatments stable.
Pozzilli, IserniaAges 18–65 - NCT05835622Recruiting
Home walking brace study to improve quality of life in MS
This study tests whether using a home “walking exoskeleton” brace can improve quality of life for people with relapsing-remitting multiple sclerosis who have moderate walking problems. You would use the device at home, and the study team will check your walking safety and comfort during and after training.
Saint-Genis-Laval, Auvergne-Rhône-AlpesAges 18 years+ - NCT06270641Recruiting
Increasing physical activity for adults with MS
This study tests whether using a phone app (ExerciseRx) can help people with multiple sclerosis become more active. You may be able to join if you are not currently very active and can walk without needing a cane or walker.
Seattle, WashingtonAges 18 years+ - NCT06433765Recruiting
BRIUMVI and pregnancy safety in multiple sclerosis
This study looks at the effects of the MS medication BRIUMVI on pregnancy and baby health. It compares women who took BRIUMVI during pregnancy to those who did not.
Wilmington, North CarolinaAges 15–50 - NCT06463743RecruitingPhase 2
Metformin for aging people with MS
This study tests whether metformin, a common diabetes drug, can help people with multiple sclerosis (MS) as they age. It may be used alone or added to your current MS treatment, and the goal is to see if it slows down aging-related changes in MS.
Buffalo, New YorkAges 55–75 - NCT06735053Recruiting
Virtual reality physiotherapy for multiple sclerosis patients
This trial tests whether virtual reality exercises can help people with advanced multiple sclerosis improve their movement and walking. You may qualify if you need two walking aids and your MS has been stable for the last six months.
Móstoles, MadridAges 18–70 - NCT06764563Recruiting
Mediterranean diet study for multiple sclerosis quality of life
This trial tests whether following a Mediterranean diet can improve quality of life for people with multiple sclerosis (MS). It aims to find a dietary approach that may help manage symptoms and improve well-being.
Tel Aviv, IsraelAges 18–70 - NCT06809192Recruiting
Cognitive behavioral therapy for multiple sclerosis fatigue
This study will test different parts of cognitive behavioral therapy to see which ones help with fatigue in people with multiple sclerosis. You will participate in sessions that may involve changing thoughts about fatigue, scheduling activities, or addressing related emotions like depression or anxiety.
Seattle, WashingtonAges 18 years+ - NCT06849882Recruiting
Balance test study for people with multiple sclerosis
This study will test whether a simple balance test (the Dubousset Functional Test) is reliable and accurate for people with MS. If you have mild disability and can stand without help, you may be able to join.
Kayseri, KayseriAges 18–65 - NCT06901687RecruitingPhase 2
Home brain stimulation for depression in MS
This study tests whether a special, gentle brain stimulation device you can use at home (called tDCS) can help improve depression symptoms in people with multiple sclerosis. You will be supervised over video during the sessions to make sure everything goes smoothly.
New York, New YorkAges 18–65 - NCT06964581Recruiting
At-home cognitive training for multiple sclerosis
This study tests a at-home thinking and memory training program for people with multiple sclerosis. It aims to help improve mental skills like memory, attention, and planning through remote sessions.
Verona, veronaAges 18–65 - NCT06968676Recruiting
Mixed reality for arm rehab in multiple sclerosis
This trial tests if mixed reality (a blend of real and virtual environments) can improve arm and hand function in people with multiple sclerosis. It may help you move your arm better and with less stiffness.
Leganés, MadridAges 18 years+ - NCT07011914Recruiting
MS care study for young adults
This study looks at how to improve care for young adults with relapsing-remitting MS. It focuses on people who are Black, Hispanic, or have limited income.
Birmingham, AlabamaAges 18 years+ - NCT07139743RecruitingPhase 1
Obe-cel for progressive multiple sclerosis that is getting worse
This study tests a new treatment called obe-cel, a type of CAR T-cell therapy, for people with progressive multiple sclerosis that hasn't responded to other treatments. It aims to see if this therapy can slow or stop the disease from getting worse.
Redwood City, CaliforniaAges 18–60 - NCT07333222Recruiting
Testing a suit to help movement after stroke or MS
This study tests whether wearing a special suit (Mollii) that sends gentle electrical pulses to the body can help improve movement, balance, and daily life for people who have had a stroke or have multiple sclerosis. The suit is meant to calm overactive muscles and help you move better.
Kaposvár, Somogy CountyAges 18–99 - NCT00001248Recruiting
MRI Brain Imaging Study for Multiple Sclerosis
This research study uses MRI (magnetic resonance imaging)—a safe, non-invasive scanner—to take detailed pictures of your brain and understand how multiple sclerosis (MS) affects it over time. You may qualify whether you have MS or are a healthy volunteer for comparison.
Bethesda, MarylandAges 18–120 - NCT01018537Recruiting
Multiple sclerosis registry for adults
This study is a registry (a voluntary database) for people diagnosed with multiple sclerosis or a related first episode called clinically isolated syndrome. It helps researchers learn about how these conditions affect people over time.
Dallas, TexasAges 18 years+ - NCT02784210RecruitingPhase 2
Steroid treatment to reduce inflammation in active MS lesions
This Phase 2 study tests whether corticosteroid medicine can reduce inflammation at the edge of active multiple sclerosis (MS) plaques seen on MRI. It may help calm “hot” areas in the brain where MS activity is happening.
Bethesda, MarylandAges 18–120 - NCT07462338Enrolling by invitation
Walking test reliability in multiple sclerosis patients
This study checks how reliable a simple walking test (Timed Up and Go) is for people with multiple sclerosis, especially when they do another task at the same time. It aims to improve how doctors measure walking ability.
Gaziantep, GaziantepAges 18–65 - NCT07106255Enrolling by invitation
Task training for multiple sclerosis patients
This trial tests a task-oriented training program to help improve hand and finger movement in people with multiple sclerosis.
Granada, GranadaAges 18 years+
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Common questions
- Are there clinical trials for multiple sclerosis?
- Yes. Clin2 currently lists 443 recruiting multiple sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Multiple Sclerosis, Relapsing-Remitting
- Multiple Sclerosis (MS) - Relapsing-remitting
- Multiple Sclerosis, Secondary Progressive
- Relapsing Multiple Sclerosis
- Multiple Sclerosis, Primary Progressive
- Progressive Multiple Sclerosis
- Multiple Sclerosis (MS) Primary Progressive
- Multiple Sclerosis (MS) Secondary Progressive
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.