Clinical trials
Nerve Block clinical trials
Below are recruiting nerve block clinical trials, each written for real people, not researchers. We’re tracking 226 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07712419Recruiting
Predicting response to knee nerve block with ultrasound
This study is testing if a type of ultrasound can help predict how well a nerve block injection will work for people with severe knee osteoarthritis. It may help doctors choose the best treatment for your pain.
IstanbulAges 45 years+ - NCT06221280Enrolling by invitation
Nerve blocks for pain after cesarean and depression
This study tests whether a nerve block (extra numbing medicine) given during a cesarean section can help with pain after delivery and may reduce the risk of postpartum depression. The trial compares the nerve block to standard care.
Kahramanmaraş, KahramanmaraşAges 18 years+ - NCT07574385RecruitingPhase 2
Nerve Block Pain Relief After Bunion Surgery
This study tests a new nerve-blocking medication (ALX006) injected near the sciatic nerve to reduce pain after bunion surgery. The goal is to see if it provides better pain relief compared to standard care.
Millcreek, UtahAges 18 years+ - NCT07634900Recruiting
Pain relief methods for children's emergency tooth root treatment
This study compares two different numbing techniques used during emergency root canal treatment in children's back lower teeth. Researchers want to see which method works better at relieving pain during the procedure.
Malatya, MalatyaAges 6–14 - NCT06633068RecruitingPhase 2
Pain relief study: nalbuphine added to numbing medicine for thyroid surgery
This study tests if adding nalbuphine to the numbing medicine (bupivacaine) given as a nerve block before thyroid surgery provides better pain relief. It is for adults having planned thyroid surgery.
Giza, الجيزةAges 18–60 - NCT07604506Enrolling by invitation
Ultrasound nerve block training for junior emergency doctors
This study teaches junior doctors in emergency medicine how to use ultrasound to safely perform nerve blocks—a pain-relief technique. Researchers will compare learning with a low-cost practice model to see if it works as well as expensive alternatives.
Kubang Kerian, KelantanAges Any age - NCT07035015Recruiting
Virtual reality vs mannequin for learning a hip nerve block
This study compares learning a specific nerve block (for the hip/upper thigh) using a self-guided virtual reality headset versus a traditional mannequin. It is for doctors and trainees at The Ottawa Hospital who want to improve their ultrasound skills for this procedure.
Ottawa, OntarioAges Any age - NCT07435675Recruiting
Nerve block to prevent agitation after ear surgery in children
This study tests if a nerve block behind the ear can help children ages 5–14 stay calm and comfortable after middle ear surgery. It may reduce confusion and restlessness when waking up from anesthesia.
Al Fayyum, Faiyum GovernorateAges 5–14 - NCT06556121Recruiting
Numbing shot for gender-affirming surgery pain
This trial tests a numbing shot given during penile inversion vaginoplasty to see if it reduces pain after surgery. It might help people manage pain with less need for strong painkillers.
Toronto, OntarioAges 18–70 - NCT07151443Recruiting
Comparing two ways to numb the arm for hand surgery in people with obesity
This study compares two ways of numbing the arm for forearm or hand surgery in people who are obese. One method places the numbing medicine near the collarbone from the front, and the other from behind the collarbone. The goal is to see which way works better.
Yenimahalle, AnkaraAges 18–80 - NCT06317870Recruiting
Nerve block vs spinal morphine for hip surgery pain
This trial compares two types of pain relief after a hip replacement: a nerve block (injecting numbing medicine near the hip) versus a small dose of morphine given through a spinal needle. It aims to find out which option works better with fewer side effects.
Lausanne, Canton of VaudAges 18 years+ - NCT07338916Recruiting
Finding the Best Dose of MEV90 for Shoulder Surgery Pain Relief
This study is testing different doses of a local anesthetic called MEV90 to find the best one for numbing the nerves during shoulder surgery. It aims to improve pain control after the operation.
ProvidenciaAges 18 years+ - NCT06568770RecruitingPhase 2/Phase 3
Comparing two nerve blocks for femur fracture surgery pain
This trial tests if one type of nerve block (PENG block) works better than another (S-FICB) for controlling pain during and after femur fracture surgery. Both blocks are guided by ultrasound to help with your recovery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT07452627Recruiting
Comparing Nerve Blocks for Sternotomy Pain
This study compares three different injection techniques (nerve blocks) to reduce pain after heart surgery that cuts through the breastbone. The goal is to find the best way to control pain with fewer side effects.
Bursa, NilüferAges 18–80 - NCT07603323Recruiting
Pain Relief Methods for Meniscus Knee Surgery
This study compares two different numbing techniques (ACB and ACB combined with BiFeS) to see which one better controls pain after meniscus surgery. The meniscus is cartilage in your knee that can tear and cause pain.
AnkaraAges 18–65 - NCT06233318Recruiting
Pain block for open heart surgery recovery
This study tests a nerve block given during open heart surgery to improve pain control. It might help patients recover with less discomfort.
Columbus, OhioAges 18 years+ - NCT07153263Recruiting
Testing a new numbing shot for lung nodule localization
This study tests a new type of numbing injection (called a retro-superior costotransverse ligament space block) to see how well it spreads and numbs the area during CT-guided lung nodule localization. The goal is to find better ways to keep you comfortable during the procedure.
Nanjing, JiangsuAges 18–80 - NCT06239649Recruiting
Nerve block before knee replacement for faster recovery
This trial tests whether a numbing injection (nerve block) around the knee before surgery can help you recover faster and feel less pain after a total knee replacement. It is for people with knee osteoarthritis who are ready for their first knee replacement surgery.
Denizli, PamukkaleAges 40–85 - NCT06402149Enrolling by invitation
Comparing two ways to numb the arm for surgery
This trial tests two different methods for numbing the arm (infraclavicular block) before upper extremity surgery. It aims to find out which approach works better to block pain.
AnkaraAges 18 years+ - NCT06851533Recruiting
Pain relief methods for lumbar microsurgery recovery
This trial compares two different types of nerve blocks to see which one reduces the need for strong pain medicine after lumbar microsurgery. It may help patients have better pain control and fewer side effects from opioids.
IstanbulAges 18–80 - NCT06662461Recruiting
Nerve block for stubborn migraines: Stellate vs occipital
This trial tests which nerve block works better for stubborn migraines: one on the stellate ganglion (a cluster of nerves in the neck) or the greater occipital nerve (at the back of the head). They will also check how these blocks affect a chemical linked to migraine pain. If you have chronic migraines that haven't improved with multiple treatments, you may be eligible.
CairoAges 18 years+ - NCT06183528Recruiting
Numbing shot for recovery after hip replacement
This study looks at a special numbing shot around the hip joint to see if it helps people recover faster and feel better after total hip replacement surgery. It may help reduce pain and improve your recovery.
Istanbul, UmraniyeAges 40–85 - NCT06183541Recruiting
Nerve block for hip fracture surgery pain
This study tests a special numbing medicine injection (called a pericapsular nerve group block) to see how well it controls pain during and after hip fracture surgery. It might help people have less pain and recover more comfortably.
Istanbul, UmraniyeAges 30–85 - NCT07739303Recruiting
Nerve block comparison for shoulder surgery
This study compares two types of numbing injections (nerve blocks) given before shoulder surgery to see which one provides better pain relief while keeping your diaphragm (the muscle that helps you breathe) working well.
Yenimahalle, AnkaraAges 18–65
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Common questions
- Are there clinical trials for nerve block?
- Yes. Clin2 currently lists 226 recruiting nerve block studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nerve block trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nerve block trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.