Clinical trials
Nerve Block clinical trials
Below are recruiting nerve block clinical trials, each written for real people, not researchers. We’re tracking 221 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06706375Recruiting
Comparing two types of penile nerve blocks for child circumcision
This study tests two ways of numbing the penis before circumcision in children. The goal is to see which method works better and causes less discomfort.
Lausanne, Canton of VaudAges Up to 17 years - NCT07397117Recruiting
Ultrasound-guided nerve block for sciatica pain
This trial tests if an ultrasound-guided nerve block can provide better pain relief for sciatica compared to standard care. If you have severe leg pain from sciatica, this study might help you find effective pain control.
San Francisco, CaliforniaAges 18 years+ - NCT06810375RecruitingPhase 3
Nerve Blocks for Pain After Video-Assisted Lung Surgery
This trial tests two different numbing shots (nerve blocks) to see which one works better for pain after video-assisted lung surgery. One block is placed near the spine, and the other is between the ribs. The goal is to find the best way to keep you comfortable after surgery.
Washington D.C., District of ColumbiaAges 18–90 - NCT07096765Recruiting
Comparing two injection speeds for pain relief after gallbladder surgery
This study compares two different speeds of giving a pain-blocking injection during keyhole gallbladder surgery, to see which one works better. You might join if you are otherwise healthy or have mild health issues.
BursaAges 18–65 - NCT07794527Recruiting
Nerve blocks to improve recovery after heart bypass surgery
This study tests whether giving multiple nerve blocks (numbing injections near nerves) during off-pump heart bypass surgery can improve your recovery and pain control. It aims to see if these blocks help you feel better and recover faster after surgery.
CairoAges 18–65 - NCT05507164RecruitingPhase 2
Study tests a jaw nerve block in healthy people
This trial studies how a “temporomasseteric nerve block” (a numbing shot near jaw muscles) works in healthy volunteers. It’s mainly looking at safety and how people respond—so it’s not for treating an existing jaw pain condition.
Newark, New JerseyAges 18–64 - NCT07423910Recruiting
Numbing injections for better recovery after hernia surgery
This study looks at two types of numbing injections (TAP and RS blocks) to see which helps people recover better after groin hernia surgery. If you are having a planned single-side hernia repair, you might qualify to join.
TampereAges 18 years+ - NCT03906617RecruitingPhase 4
Pain-relief shots for lung surgery: three drug options compared
This study compares different pain-relief medications given during lung surgery to see which one controls pain better. It may help people have less post-surgery pain after robotic wedge resection or lobectomy.
Camden, New JerseyAges 18–90 - NCT07775053Enrolling by invitation
Pain relief study for breast cancer surgery
This study tests whether adding tramadol to a standard numbing medicine (ropivacaine) makes pain control better after breast cancer surgery. If you're having a mastectomy, this could help reduce pain and improve recovery.
Sargodha, Punjab ProvinceAges 20–70 - NCT07386626Recruiting
Tegileridine and nerve block for lung surgery pain
This study looks at whether adding tegileridine to a nerve block (numbing the nerves between the ribs) can reduce pain after removing part of a lung. It might help you need fewer pain medicines and feel more comfortable after surgery.
Wuhan, HubeiAges 18–75 - NCT06871605Recruiting
Nerve blocks for chronic groin pain after hernia surgery
This study compares two types of nerve blocks (injections near the nerves) to treat chronic groin pain after hernia surgery. The goal is to find which block provides better pain relief.
AnkaraAges 18 years+ - NCT06590402RecruitingPhase 4
Nerve blocks for pain relief after kids' knee surgery
This study compares two types of nerve blocks to manage pain after knee surgery in children and teens. It is for patients aged 8 to 18 having a first-time ACL or MPFL reconstruction.
New York, New YorkAges 8–18 - NCT07429669Recruiting
Comparing shoulder nerve blocks for pain and breathing
This study compares two different shoulder nerve blocks to see which one provides better pain relief after shoulder surgery while also checking how they affect your breathing. If you are having a shoulder arthroscopy, you may be eligible to help find the safest and most effective pain control option.
Yenimahalle, AnkaraAges 18–65 - NCT06460792Recruiting
Ultrasound-guided nerve blocks database study
This trial is building a database to study ultrasound-guided nerve blocks (injecting numbing medicine around nerves using ultrasound). It may help researchers learn how to better manage pain.
HillerødAges 2 years+ - NCT04642352Recruiting
Nerve block injections for long-lasting nerve cough
This trial studies an office-based injection to calm a specific nerve in the neck to treat chronic cough that seems to come from nerve irritation (“neurogenic/sensory neuropathic” cough). It may help people whose cough has lasted at least 8 weeks and continues despite standard treatments for common cough causes.
Birmingham, AlabamaAges 18 years+ - NCT07853170Recruiting
Comparing 3 vs 5-needle knee nerve blocks for arthritis pain
This study compares two ways of numbing the nerves around the knee to see which gives better pain relief and improves quality of life for people with knee osteoarthritis. It might help you decide if a nerve block is a good option for your knee pain.
Tanta, El-GharbiaAges 18 years+ - NCT06374524Recruiting
Nerve block for spontaneous intracranial hypotension headache
This trial tests a nerve block injection (behind the ear) to see if it can ease the severe headache pain that happens when upright due to spinal fluid leaks. If you have spontaneous intracranial hypotension and your pain is high when standing, this treatment might help.
Toronto, OntarioAges 18 years+ - NCT07284615Recruiting
Nerve Block vs. Wound Injection for Hip Replacement Pain
This trial compares two pain-relief methods after hip replacement surgery: a nerve block (numbing the hip area) versus a numbing injection into the wound. The goal is to see which provides better pain control.
Cinisello Balsamo, MilanoAges 18 years+ - NCT06735027Recruiting
Steroid shot vs nerve block for shoulder arthritis
This trial compares two kinds of injections for shoulder pain caused by arthritis or rotator cuff problems. The goal is to see which one works better for pain relief.
Minneapolis, MinnesotaAges 18–99 - NCT06733012Recruiting
Nerve block trial for heart failure patients
This trial tests a nerve block procedure to improve heart function in people with heart failure and reduced pumping ability. It aims to see if blocking certain nerves can help you feel better and be more active.
Durham, North CarolinaAges 18 years+ - NCT04880707RecruitingPhase 2
Pain medication options for lower wisdom tooth removal
This study compares pain-medication approaches during and after removing at least one lower impacted wisdom tooth (a tooth that’s stuck). It may help find a safer or more effective way to control dental pain after surgery.
Newark, New JerseyAges 18 years+ - NCT06684249Recruiting
Comparing nerve block and Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (injection near the nerves in the head) and Botox injections. It aims to see which one works better to reduce headache days and improve quality of life.
Zagazig, Sharqia ProvinceAges 18–65 - NCT05969561Recruiting
Ultrasound-guided nerve block for hip-fracture pain in the ER
This trial tests whether an emergency doctor can safely and effectively place a pain-relieving nerve block in the thigh using ultrasound for people with hip fractures. It may help reduce pain while you are in the emergency department.
Douliu, Yunlin CountyAges 20 years+ - NCT05372393Recruiting
Carpal tunnel surgery with local anesthesia, with or without nerve block
This study compares two ways of giving pain control during carpal tunnel release surgery: local anesthesia alone versus local anesthesia plus a targeted nerve block. It may help find the safest and most comfortable option for people having carpal tunnel surgery.
Kuopio, Northern SavoniaAges 18 years+
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Common questions
- Are there clinical trials for nerve block?
- Yes. Clin2 currently lists 221 recruiting nerve block studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nerve block trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nerve block trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.