Clinical trials
Neuroblastoma clinical trials
Below are recruiting neuroblastoma clinical trials, each written for real people, not researchers. We’re tracking 102 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07549321RecruitingPhase 2/Phase 3
Hu14 Immunotherapy for High-Risk Neuroblastoma in Children
This study tests a new antibody-based immunotherapy called hu14 for children and young adults with high-risk neuroblastoma (an aggressive childhood cancer that has spread). The treatment is designed to help the immune system fight cancer cells.
San Francisco, CaliforniaAges 1.5 years–18 years - NCT06684639RecruitingEarly Phase 1
GD2-targeted CAR T cells for neuroblastoma
This trial tests a special immune cell treatment (GD2-CAR T cells) for children and teens with neuroblastoma that has come back or not responded to standard therapy. It aims to see if these engineered cells can find and attack the cancer.
Chengdu, SichuanAges 1–18 - NCT07537400RecruitingPhase 2
Naxitamab plus standard therapy for newly diagnosed high-risk neuroblastoma
This study tests adding two medications (naxitamab and GM-CSF) to standard chemotherapy for children and young adults with newly diagnosed high-risk neuroblastoma, a cancer of nerve cells. The goal is to help the body's immune system fight the cancer more effectively.
JerusalemAges 1–21 - NCT07516678Recruiting
Blood Tests to Track Neuroblastoma During Treatment
This study collects blood samples from neuroblastoma patients to test for tiny pieces of tumor DNA that can show how well treatment is working. By tracking these markers over time, doctors hope to better predict how patients will respond and improve care.
Guangzhou, GuangdongAges Any age - NCT06751134RecruitingPhase 1
Engineered immune cells for relapsed neuroblastoma in children
This trial tests a new type of immune cell therapy (called CNK-UT) for children whose neuroblastoma has come back or hasn't responded to standard treatments. The goal is to see if these cells can find and attack the cancer. Participation may be an option if your child's tumor has a specific marker (B7-H3) and their overall health is stable enough.
Nanjing, JiangsuAges 1–12 - NCT07399821RecruitingPhase 1/Phase 2
Imaging study of anti-GD2-800CW in neuroblastoma
This trial tests a special dye (anti-GD2-800CW) that lights up neuroblastoma cells during surgery, helping surgeons see and remove more of the tumor. It is for children with neuroblastoma who are scheduled to have surgery.
UtrechtAges 1–18 - NCT06631391RecruitingPhase 1
NK cell therapy for high-risk neuroblastoma in children
This trial tests a new natural killer (NK) cell therapy from donated umbilical cord blood for children with high-risk neuroblastoma that has come back or not responded to treatment. The goal is to see if this immune cell therapy is safe and can help fight the cancer.
Guangzhou, GuangdongAges 1 day–18 years - NCT07375563RecruitingPhase 3
Chemoimmunotherapy with NK cells for high-risk neuroblastoma
This trial tests a combination of chemotherapy, immunotherapy, and natural killer (NK) cell therapy for children with high-risk neuroblastoma or ganglioneuroblastoma that has not responded to initial treatment or has come back after treatment. The goal is to see if this approach can help destroy cancer cells more effectively.
MoscowAges 1.5 years–18 years - NCT06836505RecruitingPhase 1/Phase 2
CAR-T cell therapy for relapsed neuroblastoma and related tumors
This trial tests a new immune cell therapy (CAR-T) for people whose neuroblastoma or desmoplastic small round cell tumor has returned or not responded to standard treatments. The goal is to see if this therapy is safe and can help shrink or control the cancer.
Guangzhou, GuangdongAges 1–50 - NCT07334301RecruitingPhase 1/Phase 2
Combination treatments for relapsed high-risk neuroblastoma
This trial is testing different combinations of medicines for children with high-risk neuroblastoma that has come back. It has two paths: one for children whose disease has relapsed only once, and another for those whose disease has come back more than once. The goal is to find which treatments work best.
SydneyAges 1 year+ - NCT06933394RecruitingPhase 2
Arsenic trioxide with targeted drugs and chemo for high-risk neuroblastoma
This trial tests adding arsenic trioxide to standard chemotherapy and targeted drugs for children with stage 4 or M neuroblastoma. The goal is to see if this combination helps patients who have advanced disease.
Guangzhou, GuangdongAges 1.5 years–18 years - NCT07195500Recruiting
Imaging scans for neuroblastoma and related tumors
This trial uses special PET/CT or SPECT/CT scans that light up certain types of tumor cells (neuroblastoma and pheochromocytoma/paraganglioma). The scans help doctors see where the cancer is, how far it has spread, and whether treatment is working.
Nanjing, JiangsuAges 6 months+ - NCT07100704RecruitingPhase 2
Nivolumab for recurrent olfactory neuroblastoma
This trial tests the drug nivolumab for people with a rare nasal tumor (olfactory neuroblastoma) that has come back or spread and cannot be treated with surgery or radiation. You must have already tried chemotherapy and it stopped working. The goal is to see if nivolumab can shrink the tumor or slow its growth.
Kashiwa, ChibaAges 18 years+ - NCT07085338RecruitingPhase 2
N-803 with chemoimmunotherapy for relapsed neuroblastoma
This trial tests adding a new drug called N-803 to a standard chemo-immunotherapy combination for children and young adults with high-risk neuroblastoma that has come back or not responded to previous treatments. The goal is to see if this combination works better at fighting the cancer.
San Francisco, CaliforniaAges Up to 30 years - NCT07067346RecruitingEarly Phase 1
IR-101 for relapsed or refractory neuroblastoma
This early-phase trial tests a new drug called IR-101 for children with high-risk neuroblastoma that has come back or isn't responding to treatment. It aims to see if the drug is safe and can help shrink tumors that show up on a MIBG scan.
Chengdu, SichuangAges 1 year+ - NCT07064746Recruiting
Special imaging scans for children with neuroblastoma
This study tests two special types of imaging scans that look for neuroblastoma tumors. The imaging uses safe radioactive tracers to help doctors better see the cancer and plan treatment.
Nanjing, JiangsuAges Up to 18 years - NCT06995872RecruitingPhase 1
Study of rhIL-15 with immunotherapy and chemo for neuroblastoma
This trial tests a new combination of drugs (rhIL-15, dinutuximab, irinotecan, and temozolomide) for children and young adults whose neuroblastoma has come back or hasn't responded to other treatments. The goal is to see if this mix can help shrink or control the cancer.
Bethesda, MarylandAges 3–35 - NCT06013618RecruitingPhase 2
Naxitamab for high-risk or relapsed neuroblastoma in children
This trial tests a targeted antibody called naxitamab (hu3F8) for children with high-risk neuroblastoma that has come back or is hard to treat. It aims to see if this therapy can help shrink or control the cancer with an acceptable safety profile.
Guangzhou, GuangdongAges 1 year+ - NCT06852807Recruiting
New PET scan for neuroblastoma in children
This trial uses a special PET scan called 18F-mFBG to take pictures of neuroblastoma tumors. It helps doctors see where the cancer is and whether treatment is working.
Hangzhou, ZhejiangAges Up to 18 years - NCT06485947RecruitingPhase 1
Study testing dinutuximab beta with chemotherapy for neuroblastoma
This trial combines the immunotherapy drug dinutuximab beta with two different chemotherapy regimens to see if it works better for children with high-risk neuroblastoma that has spread. It may be an option for newly diagnosed patients who have not had cancer treatment before.
Utrecht, UtrechtAges 1.5 years–18 years - NCT06818916Recruiting
A study of hetrombopag to help platelets recover after stem cell transplant for neuroblastoma
This trial tests if a drug called hetrombopag can help children with neuroblastoma recover their platelet counts more quickly after their own stem cells are transplanted. It aims to reduce the time needed for platelet engraftment and lower the risk of bleeding.
BeijingAges Up to 18 years - NCT06721689RecruitingPhase 1/Phase 2
PEEL-224 with chemo for pediatric solid tumors
This trial tests a new drug called PEEL-224 combined with two chemotherapy medicines (vincristine and temozolomide) for children and young adults with certain solid tumors that have come back or not responded to treatment. It aims to see if this combination is safe and works against the cancer.
Los Angeles, CaliforniaAges 1–30 - NCT06703944Enrolling by invitation
Predicting neuroblastoma spread risk
This trial uses a risk model to help detect if neuroblastoma has spread to the bone or bone marrow in newly diagnosed patients. It aims to improve how doctors identify metastasis without needing extra special tests.
Shanghai, Shanghai MunicipalityAges Any age - NCT06607692RecruitingPhase 1/Phase 2
LuPARPed: Targeted radiation plus olaparib for certain childhood cancers
This trial tests a combination of a radioactive drug (Lutathera) and a targeted pill (olaparib) for children and teens whose solid tumors have come back or not responded to treatment and show high levels of a specific receptor (SSTR) on scans. The goal is to see if this two-drug approach can shrink tumors or stop them from growing.
Boadilla del Monte, MadridAges 3 years+
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Common questions
- Are there clinical trials for neuroblastoma?
- Yes. Clin2 currently lists 102 recruiting neuroblastoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuroblastoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuroblastoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Children’s Oncology Support FundChildren with cancer and the families caring for them.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.