Clinical trials
Neurocognitive Disorders clinical trials
Below are recruiting neurocognitive disorders clinical trials, each written for real people, not researchers. We’re tracking 70 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06423547Recruiting
Predicting confusion after surgery in older adults
This study looks at older patients (65 and older) who have had surgery and anesthesia. It aims to find who is at risk for confusion (delirium) and memory problems afterward. The goal is to help doctors prevent these issues.
BeijingAges 65–100 - NCT06776848RecruitingPhase 1/Phase 2
Lithium for TBR1-related neurodevelopmental disorder
This trial tests whether taking lithium for 2 years can improve symptoms in people with a TBR1 gene change that causes neurodevelopmental challenges. It aims to see if lithium is safe and helpful for this condition.
DijonAges 6 years+ - NCT06718140Enrolling by invitationPhase 1
Ultrasound for memory in mild cognitive decline
This study tests if a non-invasive ultrasound treatment can help memory in people with mild cognitive impairment (mNCD) and healthy older adults. It involves MRI scans and focused ultrasound sessions.
Charleston, South CarolinaAges 50–85 - NCT06700291Recruiting
Frailty and thinking problems after surgery in older adults
This study looks at how frailty (a state of being physically weak and less resilient) before hip or knee replacement surgery affects thinking and memory problems after surgery in older adults. It aims to help identify patients who may need extra support.
TbilisiAges 65 years+ - NCT06636786RecruitingPhase 2
Medication to reduce stress symptoms after a car accident
This study tests whether a medication placed under the tongue can help prevent or reduce stress-related symptoms, like anxiety or post-traumatic stress, after a motor vehicle crash. It may help you feel better in the weeks following the accident.
Birmingham, AlabamaAges 18–55 - NCT06523296Recruiting
Antibodies and thinking problems in myasthenia or Alzheimer's
This study looks at whether certain antibodies are linked to memory and thinking problems in people with myasthenia gravis or Alzheimer's disease. It involves a one-time use of leftover spinal fluid from a previous diagnostic test.
Nice, Alpes MaritimesAges 18 years+ - NCT06452147Recruiting
Anesthesia types for preventing confusion after hip surgery in older adults
This study looks at different ways to give anesthesia during hip surgery to help older patients think and remember better afterward. It may help prevent confusion or memory problems that sometimes happen after surgery.
Dongyang, ZhejiangAges 65 years+ - NCT06237218Recruiting
Occupational therapy to prevent falls in older adults with dementia
This program tests whether a special type of home-based occupational therapy (called COTID) can help older adults with dementia avoid falling again after a fall that sent them to the hospital. It compares this new approach to usual occupational therapy care.
LimogesAges 75 years+ - NCT06143488Recruiting
Clot removal versus medication for mild stroke with large vessel blockage
This trial compares a procedure to remove the blockage (endovascular therapy) with the best medications alone for people who have a mild stroke caused by a large blocked artery in the brain. The goal is to see if the procedure can improve recovery better than medicine alone.
Wuhu, AnhuiAges 18 years+ - NCT05929703Recruiting
Caring for hospitalized older adults
This study tests a new approach to caring for older adults in the hospital to prevent confusion (delirium). It involves having a family member or care partner stay with the patient during the hospital stay.
Orange, CaliforniaAges 70 years+ - NCT05754567Recruiting
Study brain and development outcomes in CONCEPTT kids
This study looks at children’s neurodevelopment (how the brain, learning, and development are going) whose mothers took part in the earlier CONCEPTT trial. It may help researchers understand how having type 1 diabetes in pregnancy can relate to a child’s development.
Calgary, AlbertaAges 6 years+ - NCT05586581RecruitingPhase 1/Phase 2
PET and MRI scans to study brain changes in treated HIV
This study uses PET and MRI scans, plus blood tests and memory/thinking questionnaires, to understand what drives brain problems in people living with HIV even during treatment. It may help researchers learn why symptoms happen and how treatment relates to brain function.
New Haven, ConnecticutAges 18–80 - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT05888961Recruiting
Study of taste changes in people with memory problems
This study tracks how taste perception works in people with different stages of memory and thinking problems, including mild to moderate Alzheimer-type conditions. It uses non-painful taste testing and brain-wave measurements to understand changes over time and may help improve how these conditions are assessed.
DijonAges 18 years+ - NCT04971850Recruiting
Sleep study for children with possible breathing sleep problems
This trial looks at sleep-related breathing problems (“sleep-disordered breathing”) in children and young adults and how they may affect thinking and memory using sleep study testing plus neurocognitive (thinking) assessments. It may help doctors better understand symptoms and identify who could benefit from treatment.
ParisAges 1–20 - NCT06781905Recruiting
Brain effects of ALK/ROS1 lung cancer drugs and quality of life
This study looks at how certain targeted therapy drugs for ALK/ROS1-positive lung cancer may affect thinking, memory, mood, and mental health. It aims to build a special care and research path where patients and researchers work together to understand and manage these side effects.
BronAges 18 years+ - NCT05776056RecruitingPhase 4
Methylphenidate for PTSD with memory and thinking problems
This study tests whether methylphenidate, a medication commonly used for attention issues, can help veterans with PTSD who also have memory or concentration problems. The goal is to see if it improves these cognitive symptoms.
Birmingham, AlabamaAges 18–65 - NCT07763392Recruiting
Normal cognitive test scores for adults
This study is testing a voice-controlled digital platform to measure normal memory and thinking abilities in healthy adults. By participating, you would help create a baseline of normal scores that doctors can use to compare against when assessing people with thinking problems.
Carlsbad, CaliforniaAges 18–100 - NCT05913544Recruiting
Integrative therapy for young adults with borderline personality disorder
This trial tests a short integrative therapy program along with repeated thinking (neurocognitive) and mental health assessments for young adults with borderline personality disorder (BPD). It may help improve symptoms and cognitive functioning by combining structured therapy and targeted evaluations.
NîmesAges 16–25 - NCT05336188Enrolling by invitation
Smartphone help to prevent relapse in opioid use disorder
This study looks at whether a smartphone-based program can help people avoid relapse from opioid use disorder. Some participants may also do brain scans to better understand the brain changes behind relapse prevention.
Little Rock, ArkansasAges 18 years+ - NCT05565833RecruitingPhase 2
Online sleep program for insomnia and thinking problems
This Phase 2 study tests an internet-based sleep program to help older adults with insomnia and related thinking difficulties. It may help improve sleep and reduce how much tiredness and sleep disruption affect daily life.
Charlottesville, VirginiaAges 65 years+ - NCT05802680Recruiting
Near-infrared light study for brain effects in adults
This study tests how non-invasive near-infrared light may affect brain function. You may be able to join if you’re an adult, since there are no other listed eligibility restrictions.
Austin, TexasAges 18 years+
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Common questions
- Are there clinical trials for neurocognitive disorders?
- Yes. Clin2 currently lists 70 recruiting neurocognitive disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neurocognitive disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neurocognitive disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.