Clinical trials
Neurocognitive Disorders clinical trials
Below are recruiting neurocognitive disorders clinical trials, each written for real people, not researchers. We’re tracking 77 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05929703Recruiting
Care approach for hospitalized older adults at risk of confusion
This trial tests new ways to help hospitalized older adults (and their family/care partners) stay comfortable and avoid or reduce episodes of acute confusion. It focuses on people who are likely to develop delirium during their hospital stay.
Orange, CaliforniaAges 70 years+ - NCT06036095RecruitingPhase 4
Comparing two types of anesthesia in older adults having surgery
This study compares two types of general anesthesia for older adults (70+) having planned non-heart, non-brain surgery that lasts at least 2 hours. The goal is to see which type might be better for preserving thinking and memory after surgery.
Portland, OregonAges 70–110 - NCT06143488Recruiting
Clot removal vs. best medicine for mild stroke with large vessel blockage
This trial tests whether removing a blood clot from a large brain artery is better than standard medical care for people who have a mild stroke (NIHSS score 2-5) but still have symptoms like trouble speaking, weakness, or confusion. It is for patients who can be treated within 24 hours of their last known well time.
Wuhu, AnhuiAges 18 years+ - NCT06186089Recruiting
How stomach surgery affects gut bacteria and your thinking
This study looks at how having stomach cancer surgery changes your gut bacteria and thinking abilities. Researchers want to understand if these changes affect memory or brain function after the operation.
Wuhan, HubeiAges 40–80 - NCT06237218Recruiting
Occupational therapy to prevent falls in older adults with dementia
This program tests whether a special type of home-based occupational therapy (called COTID) can help older adults with dementia avoid falling again after a fall that sent them to the hospital. It compares this new approach to usual occupational therapy care.
LimogesAges 75 years+ - NCT06416514Recruiting
Personalized help for mild behavioral changes
This study tests a personalized program to support people with mild behavioral impairment (changes in mood, motivation or social behavior) and see if it can improve their health. If you are 60 or older and notice these changes, this trial might help you get tailored support.
Fuzhou, FujianAges 60 years+ - NCT06423547Recruiting
Predicting confusion after surgery in older adults
This study looks at older patients (65 and older) who have had surgery and anesthesia. It aims to find who is at risk for confusion (delirium) and memory problems afterward. The goal is to help doctors prevent these issues.
BeijingAges 65–100 - NCT06452147Recruiting
Anesthesia and brain health after hip surgery in older adults
This trial is testing different types of anesthesia to see how they affect brain function (memory, thinking) after hip fracture surgery in older adults. It aims to find the safest approach for elderly patients.
Wenzhou, ZhejiangAges 65 years+ - NCT06466083Recruiting
Thinking changes after spine surgery in older adults
This study looks at why some older adults have confusion or memory changes after spine surgery. It aims to find patterns that could help prevent these problems.
BeijingAges 65–100 - NCT06466096Recruiting
Thinking and memory after stomach/colon cancer surgery
This study looks at how older adults (65+) think and remember after surgery for gastrointestinal cancer. It compares those who have temporary confusion after surgery with those who don't, to understand long-term changes in brain function.
BeijingAges 65–100 - NCT06523296Recruiting
Antibodies and thinking problems in myasthenia or Alzheimer's
This study looks at whether certain antibodies are linked to memory and thinking problems in people with myasthenia gravis or Alzheimer's disease. It involves a one-time use of leftover spinal fluid from a previous diagnostic test.
Nice, Alpes MaritimesAges 18 years+ - NCT06631742Recruiting
Exergaming for dementia: a fun exercise trial
This trial tests whether playing interactive video games that combine exercise and thinking challenges (called 'exergaming') can help people with dementia. It aims to see if this fun way to move and think can improve memory, daily function, and quality of life.
Wetzikon, Canton of ZurichAges Any age - NCT06636786RecruitingPhase 2
Preventing PTSD after a car crash with a dissolving tablet
This study tests a dissolving tablet (cyclobenzaprine) placed under the tongue to see if it can help prevent PTSD and reduce pain symptoms after a car accident. You would take the medication for 14 days and be followed for about 8 weeks.
Birmingham, AlabamaAges 18–55 - NCT06700291Recruiting
Frailty and thinking problems after surgery in older adults
This study looks at how frailty (a state of being physically weak and less resilient) before hip or knee replacement surgery affects thinking and memory problems after surgery in older adults. It aims to help identify patients who may need extra support.
TbilisiAges 65 years+ - NCT06701630Recruiting
Italian study of daily thinking and memory scales
This study is testing new questionnaires to better understand everyday thinking and memory problems in older adults. It aims to improve how doctors identify and track conditions like mild cognitive impairment and early dementia.
Milan, MichiganAges 60 years+ - NCT07569887Recruiting
Brain Imaging Study of Arteriovenous Malformations Before and After Surgery
This research study uses special brain imaging scans to understand how an unruptured arteriovenous malformation (an abnormal tangle of blood vessels in the brain) affects blood flow and thinking abilities before and after surgical treatment. The goal is to learn how surgery impacts brain function and cognition in patients like you.
Montpellier, FranceAges 18 years+ - NCT06846658Recruiting
Finding early signs of Parkinson's and related diseases
This study looks at cells from the nose, blood, and urine to find early markers for Parkinson's disease, similar conditions, and memory problems linked to Lewy bodies. If you have one of these conditions, joining could help improve early diagnosis.
Sesto Fiorentino, FIAges Any age - NCT07294963Recruiting
Lifestyle changes to help thinking and memory in fatty liver disease
This trial tests whether lifestyle changes can prevent cognitive decline in people with non-alcoholic fatty liver disease. If you have fatty liver and are between 18 and 42 years old, you may be able to join.
Peshawar, KPKAges 18–42 - NCT07418008Recruiting
Thinking and memory study for people with liver cirrhosis
This study is creating a new test to measure thinking and memory problems in people with liver cirrhosis. It may help doctors find these problems earlier.
Ambāla, HaryanaAges 18–75 - NCT07589348Recruiting
Brain Function After Gynecologic Surgery
This study measures whether women experience changes in thinking and memory after having gynecologic surgery (removal of uterus and/or ovaries). Researchers want to understand how anesthesia and surgery affect the brain and identify who might be at risk.
İzmit, KocaeliAges 18 years+ - NCT06718140Enrolling by invitationPhase 1
Ultrasound for memory in mild cognitive decline
This study tests if a non-invasive ultrasound treatment can help memory in people with mild cognitive impairment (mNCD) and healthy older adults. It involves MRI scans and focused ultrasound sessions.
Charleston, South CarolinaAges 50–85 - NCT05888961Recruiting
Study of taste changes in people with memory problems
This study tracks how taste perception works in people with different stages of memory and thinking problems, including mild to moderate Alzheimer-type conditions. It uses non-painful taste testing and brain-wave measurements to understand changes over time and may help improve how these conditions are assessed.
DijonAges 18 years+ - NCT04971850Recruiting
Sleep study for children with possible breathing sleep problems
This trial looks at sleep-related breathing problems (“sleep-disordered breathing”) in children and young adults and how they may affect thinking and memory using sleep study testing plus neurocognitive (thinking) assessments. It may help doctors better understand symptoms and identify who could benefit from treatment.
ParisAges 1–20 - NCT06781905Recruiting
Brain effects of ALK/ROS1 lung cancer drugs and quality of life
This study looks at how certain targeted therapy drugs for ALK/ROS1-positive lung cancer may affect thinking, memory, mood, and mental health. It aims to build a special care and research path where patients and researchers work together to understand and manage these side effects.
BronAges 18 years+
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Common questions
- Are there clinical trials for neurocognitive disorders?
- Yes. Clin2 currently lists 77 recruiting neurocognitive disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neurocognitive disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neurocognitive disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.