Clin2
NCT05776056Possibly a fitRecruiting

Methylphenidate for PTSD with memory and thinking problems

Posttraumatic Stress Disorder (PTSD)

Treatments studied

Part of Brain & nervous system, Injuries & trauma, Mental health clinical trials.

This study tests whether methylphenidate, a medication commonly used for attention issues, can help veterans with PTSD who also have memory or concentration problems. The goal is to see if it improves these cognitive symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
70 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are a veteran of the U.S. military.
  • You have been diagnosed with PTSD and currently have symptoms like flashbacks or nightmares.
  • You have noticeable memory, focus, or thinking difficulties.
  • You are not currently taking certain medications (like stimulants or antidepressants) and agree to stop them before the study.
  • You are not pregnant and, if you could become pregnant, you agree to use birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06954025Enrolling by invitation· Phase 2
MDMA therapy for PTSD inpatients

This trial tests whether high-dose MDMA, given during intensive inpatient therapy, can help people with PTSD that hasn't improved with other treatments. It takes place at a specialized trauma center and involves several therapy sessions with the drug.

Oegstgeest
NCT04452500Recruiting· Phase 2
Study drug for PTSD symptoms in Veterans

This trial tests a study medicine that blocks the effects of cortisol (a stress hormone) to reduce PTSD symptoms in Veterans. It’s meant for people with ongoing PTSD symptoms and stable treatments, and it closely checks safety because the medicine can affect sleep, mood, and heart rhythm.

Tuscaloosa, Alabama
NCT05746572Enrolling by invitation· Phase 2
MDMA-assisted therapy plus exposure therapy for PTSD

This Phase 2 study tests whether MDMA combined with therapy that uses exposure (gradual confronting of trauma memories) can reduce PTSD symptoms. It may help people who meet PTSD criteria, can follow strict safety rules, and can complete medicine-session monitoring.

Atlanta, Georgia
NCT07288151Recruiting· Phase 2
MDMA with Exposure Therapy for PTSD

This trial tests whether MDMA (the drug in ecstasy) combined with a type of talk therapy called massed exposure therapy can help treat PTSD. It may be an option if standard treatments haven't worked well enough.

Atlanta, Georgia
NCT07664631Not yet recruiting· Phase 1
Testing stimulant medications for PTSD

This study tests whether stimulant medications can help treat PTSD symptoms. Researchers want to see if these medications are safe and effective for people with PTSD.

Chicago, Illinois
NCT05133804Recruiting· Phase 2
Testing two medications for PTSD attention and emotions

This Phase 2 study tests whether reboxetine or methylphenidate can improve attention and emotional or sensory problems in adults with post-traumatic stress disorder (PTSD). You may be eligible if you have a confirmed PTSD diagnosis and are able to meet medication and safety requirements.

Afula

Hear when a new Posttraumatic Stress Disorder (PTSD) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.