Clinical trials
Neurocognitive Disorders clinical trials
Below are recruiting neurocognitive disorders clinical trials, each written for real people, not researchers. We’re tracking 77 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06320639Recruiting
Driving simulator study for people with memory or thinking problems
This study uses a driving simulator to see how people with mild cognitive problems or dementia perform while driving. If you have a driver's license and are still driving or recently stopped, you may be able to join.
VilleurbanneAges 50–95 - NCT07205003Recruiting
Artery stiffness test for memory disorders
This study looks at how the stiffness of your carotid artery (the main artery in your neck) relates to memory problems. It involves a brain MRI that you may already have planned, and results could help doctors better understand certain types of dementia.
RouenAges 70 years+ - NCT07237009Recruiting
Personalized reminiscence therapy for memory loss
This trial tests a digital app that uses personal photos and memories to help people with early memory problems feel less depressed or apathetic. It's designed for seniors who have mild cognitive impairment or early dementia.
AngersAges 60 years+ - NCT07279714RecruitingPhase 2
Fisetin for mild Alzheimer's disease
This trial tests whether a supplement called fisetin can help people with mild Alzheimer's disease or mild cognitive impairment. Fisetin is a natural compound found in fruits and vegetables that may reduce aging-related changes in the body.
Toronto, OntarioAges 60 years+ - NCT07526740Recruiting
Brain Stimulation and Training for Mild Memory Loss
This study tests whether combining brain stimulation (TMS) with cognitive training games can help people with mild cognitive impairment—early memory and thinking problems. The goal is to see if this combination improves thinking abilities and slows cognitive decline.
Charleston, South CarolinaAges 60–85 - NCT04889794Recruiting
Helps pharmacists support seniors with memory problems after work changes
This study looks at whether reorganizing work in family medicine clinics changes how pharmacists review and support seniors who have major memory (cognitive) problems. It may help improve medication support and seniors’ autonomy with guidance that fits their needs.
Montreal, QuebecAges 65 years+ - NCT05741853Recruiting
Speech therapy study for bilingual people with primary progressive aphasia
This study looks at how well speech-language therapy works in bilingual people with primary progressive aphasia, a condition that gradually affects language. It also tests whether different language skills (Spanish/Catalan or Spanish/English) affect response to treatment.
Austin, TexasAges 40 years+ - NCT06615167Recruiting
Testing ALZGUARD app for diagnosing dementia
This trial tests an app called ALZGUARD that helps doctors diagnose major neurocognitive disorders (like dementia). If you are between 55 and 85 years old, you may be able to help see if the app works well and is safe.
Chuncheon, Gangwon-doAges 55–85 - NCT06606353Recruiting
Talk-to-Jo: A digital companion for memory issues
This trial tests a French-speaking digital assistant called Talk-to-Jo for people recently diagnosed with mild to moderate memory or thinking problems and their caregivers. The goal is to see if this tool helps both the person with memory issues and the person caring for them.
Montreal, QuebecAges 65 years+ - NCT06638710RecruitingPhase 2
Testing oral midazolam for care in elderly with dementia who refuse care
This trial tests if giving a medication called midazolam by mouth can help older adults with memory problems who refuse care to accept it more calmly. It is for people in certain hospital or long-term care units, with moderate to severe memory loss and a history of resisting care.
Grenoble, IsereAges 60 years+ - NCT06488807Recruiting
Smell therapy to prevent confusion after surgery
This study tests whether a simple smell-based activity before and after surgery can help prevent confusion and memory problems in older adults. It is for people 65 and older who are having a long surgery under general anesthesia.
ShanghaiAges 65 years+ - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT07038798Recruiting
Deep rTMS for mild memory problems in older adults
This trial is testing whether a non-invasive brain stimulation technique called deep rTMS can help older adults with mild memory or thinking problems. It aims to see if this treatment can improve cognitive function without major side effects.
Hamilton, OntarioAges 60–90 - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT06608589Recruiting
Improving care transitions for older adults with memory problems
This study tests a program called CoMPAS+ MNCD to help older adults with memory or thinking problems move smoothly between care settings. It also looks at how to train healthcare workers and improve services in the region.
Québec, QuebecAges 65 years+ - NCT06692309Recruiting
Can brain wave patterns predict thinking problems after heart surgery?
This study uses a brain wave recording device (EEG) during heart surgery to see if it can predict short-term confusion or memory problems after the operation. It may help doctors find and treat thinking issues earlier.
Beijing, Beijing MunicipalityAges 60 years+ - NCT04825847Recruiting
Testing brain changes after major surgery in older adults
This study looks at how memory and thinking change after major surgery in people age 70 and older. It may help doctors understand who is at risk and how to reduce problems with thinking after surgery.
Montreal, QuebecAges 70 years+ - NCT07048002Recruiting
Silent brain infarct and cognitive decline after heart surgery
This trial tests a bundle of interventions to prevent silent brain infarctions (small 'silent' strokes) and thinking problems after heart or blood vessel surgery with a heart-lung machine. If you are 60 or older and having such surgery, this study may help protect your brain health.
Beijing, Beijing MunicipalityAges 60 years+ - NCT05886114Recruiting
Lifestyle program to help older adults at risk of memory decline
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
Hangzhou, ZhejiangAges 60–80 - NCT06853405Recruiting
Nutrition program to prevent memory decline
This study tests whether nutrition-based changes can help prevent memory loss and thinking problems in people who are at higher risk for dementia. To join, you need to be between 55 and 85, have at least 4 years of schooling, and have an elevated dementia risk score.
Porto, PortugalAges 55–85 - NCT06983119Recruiting
Finding early signs of memory loss in Pavia
This study looks for early thinking and memory changes in people 50 and older who haven't been diagnosed with cognitive decline. You'll complete a quick assessment to see if further checkups might help.
Pavia, PaviaAges 18 years+ - NCT07760545Recruiting
Memory screening by video before surgery
This study tests whether doing a quick memory and thinking check over video call is as reliable as doing it in person. You would take part before your scheduled surgery to help improve how cognitive health is assessed.
Vancouver, British ColumbiaAges 65 years+ - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT05668598Recruiting
Memory check study for older adults with and without dementia
This study creates a practical tool to measure “episodic memory,” which is your ability to recall events from daily life. It includes adults age 70+ with different memory levels, to see how well the tool works for people with dementia and for those without.
LensAges 70 years+
Hear when a new Neurocognitive Disorders trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for neurocognitive disorders?
- Yes. Clin2 currently lists 77 recruiting neurocognitive disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neurocognitive disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neurocognitive disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.