Clinical trials
Neurodegenerative Diseases clinical trials
Below are recruiting neurodegenerative diseases clinical trials, each written for real people, not researchers. We’re tracking 85 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07531732Recruiting
Self-Awareness and Social Thinking in Brain Diseases
This study explores how awareness of oneself and the ability to understand others' thoughts relates to two types of brain diseases: frontotemporal dementia (a disease affecting personality and behavior) and Alzheimer's disease. The research may help doctors better understand these conditions and improve care.
ParisAges 50–80 - NCT04239079Recruiting
Study of immune-related changes in Parkinson’s and Alzheimer’s
This study looks for “autoimmune-like” (immune-system) features in brain-related diseases such as Parkinson’s and Alzheimer’s, using genetic testing and other assessments. Results may help researchers understand what drives these conditions and who might be more likely to have immune-related changes.
New York, New YorkAges 55–90 - NCT06846658Recruiting
Finding early signs of Parkinson's and related diseases
This study looks at cells from the nose, blood, and urine to find early markers for Parkinson's disease, similar conditions, and memory problems linked to Lewy bodies. If you have one of these conditions, joining could help improve early diagnosis.
Sesto Fiorentino, FIAges Any age - NCT05354622Recruiting
Genetic testing study for inherited leg stiffness
This study looks at genes (DNA) to understand an inherited condition that causes gradually worsening leg stiffness. It may help researchers learn what causes the condition and potentially guide future care.
Boston, MassachusettsAges 1 month–30 years - NCT07449117Recruiting
Brain stimulation for language in mild cognitive decline
This study tests a new type of gentle brain stimulation (called temporal interference) to see if it can improve language processing in people with mild cognitive impairment. The stimulation uses electrodes placed on the head and is done while you are in an MRI scanner.
Brno, South MoravianAges 60–80 - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT05785156Recruiting
Quick test study to predict stroke and memory disease outlook
This study tests quick new methods to measure “slowed actions” in people with stroke or memory-related brain conditions. The goal is to see whether these quick tests can help predict future outcomes and guide care.
AmiensAges 40–85 - NCT06528964Recruiting
Skin protein study for Alzheimer's, Parkinson's, and related disorders
This study looks at the skin of people with memory or movement disorders (like Alzheimer's, Parkinson's, ALS) to find proteins that may help diagnose these conditions. If you have one of these diseases or are a healthy older adult, you may be able to join by giving a small skin sample.
San Luis Potosí CityAges 45 years+ - NCT07467460Recruiting
Precision medicine trial for Parkinson's and Alzheimer's
This trial uses advanced tools to better diagnose and treat Parkinson's disease and Alzheimer's disease. It aims to personalize care based on your specific symptoms and biomarkers.
PozzilliAges 18 years+ - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT07239843Enrolling by invitation
Study of blood markers and mental health in brain diseases
This study looks at how social factors and blood markers relate to psychiatric symptoms in people with brain diseases or mental disorders. It aims to find new ways to understand and diagnose these conditions.
Barcelona, BarcelonaAges 18 years+ - NCT04715399Recruiting
Research study collecting data for neurodegenerative diseases
This study collects health information from people with neurodegenerative diseases, some family members, and healthy controls to help researchers better understand these conditions. It may help future diagnosis and research, and participation may include noninvasive checks and other procedures depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05402488Recruiting
Studying sleep recovery in adults with neurodegeneration
This study looks at how sleep “recovery” works in people with neurodegenerative diseases (conditions where abnormal proteins build up). It uses sleep recordings and sounds during sleep to see how sleep patterns relate to outcomes.
Zurich, Canton of ZurichAges 18 years+ - NCT05929144Recruiting
MRI testing to improve brain scans in neurodegenerative diseases
This study aims to improve MRI scan settings used when studying brain diseases that affect memory and movement. You would be asked to undergo MRI scanning as a healthy volunteer to help optimize the imaging process.
CaenAges 18 years+ - NCT05943002Recruiting
Track symptoms and life effects using a phone survey
This study uses patient-reported questionnaires and health/economics/psychosocial questions for people with Friedreich ataxia. It aims to better understand how the condition affects daily life and what outcomes matter most, which can help future care and research.
InnsbruckAges 12 years+ - NCT06339190Recruiting
Testing blood and voice for early dementia diagnosis
This study uses a simple blood test (neurofilament light chain) and a voice recording analysis to see if they can help diagnose dementia earlier. Researchers want to see if these markers can reliably detect brain changes in people with memory or thinking problems.
Box Hill, VictoriaAges Any age - NCT06538974Recruiting
Long-term use of an exoskeleton for leg weakness
This trial tests a walking device called an exoskeleton to help people with leg weakness or movement problems. It's designed to see if using the exoskeleton regularly over time can help improve walking or mobility.
ParisAges 18 years+ - NCT06627387Recruiting
Balance training with augmented reality for home rehab
This study tests a low-cost balance training platform that uses augmented reality to help people with balance problems from stroke or other brain conditions. It aims to see if the platform is easy and safe to use at home with a training partner.
Barcelona, BarcelonaAges 18 years+ - NCT06671236RecruitingPhase 1
Treg cell therapy for ALS
This trial tests a new type of cell therapy called regulatory T cells (Tregs) for people with neurodegenerative diseases like ALS. The goal is to see if these cells can slow down the disease.
Zhengzhou, HenanAges 18–70 - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT07137949Recruiting
Music therapy to prevent delirium in patients with memory or movement problems
This trial tests whether a music therapy session can help prevent delirium (sudden confusion) in hospitalized patients with memory or movement disorders like Parkinson's or Alzheimer's. If it works, music could become a drug-free way to keep you clearer-headed during a hospital stay.
Boston, MassachusettsAges 60 years+ - NCT07249918Recruiting
Wearable devices for dementia care in rural Taiwan
This trial tests if wearable devices can help monitor and improve behavioral symptoms like agitation, depression, or sleep problems in people with Alzheimer's or mild cognitive impairment. It also involves their caregivers.
Beigang, YunlinAges Any age - NCT07268079Recruiting
Testing a VR app for brain and thinking skills
This study is testing a virtual reality app called VIRADIA to see if it can help check brain and thinking skills. Doctors are looking for people with and without a neurological condition like Parkinson's or multiple sclerosis to take part.
Nitra, Nitra RegionAges 18–80 - NCT07285954Recruiting
Mindful walking study for brain health
This study tests whether a mindful walking program (audio-guided walks) can help people with brain conditions like multiple sclerosis, Parkinson's, or Alzheimer's feel more resilient. If you join, you will be randomly assigned to the walking program or a control group, and you'll wear a Fitbit and do some in-person brain tests.
Urbana, IllinoisAges 18–110
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Common questions
- Are there clinical trials for neurodegenerative diseases?
- Yes. Clin2 currently lists 85 recruiting neurodegenerative diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neurodegenerative diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neurodegenerative diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.