Clinical trials · California
Obesity & Overweight clinical trials in California
We’re tracking 64 recruiting obesity & overweight studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Escondido, CaliforniaAges 18 years+ - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
San Diego, CaliforniaAges 18 years+ - NCT07607587RecruitingPhase 1
Testing a new weight-loss drug for people who couldn't tolerate GLP-1 shots
This study tests a new injectable medication called cagrilintide for people with obesity who had to stop GLP-1 drugs (like Ozempic or Wegovy) because of stomach problems. The goal is to see if cagrilintide causes fewer stomach side effects while still helping with weight.
Walnut Creek, CaliforniaAges 18 years+ - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
Huntington Beach, CaliforniaAges 18 years+ - NCT07202884RecruitingPhase 3
Orforglipron for Women with Stress Incontinence and Overweight
This study tests an oral medication called orforglipron to see if it helps women with stress urinary incontinence who are also overweight or have obesity. The medicine may reduce leaking episodes and also help with weight loss.
Los Angeles, CaliforniaAges 18 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Lynwood, CaliforniaAges 18 years+ - NCT07724340RecruitingPhase 2
Study of AT673 plus semaglutide for type 2 diabetes and weight loss
This study tests a new medication called AT673 combined with semaglutide (Wegovy) to help people with type 2 diabetes and overweight or obesity lose weight and improve blood sugar. It is for people who have tried diet and exercise to lose weight but haven't had success.
Anaheim, CaliforniaAges 18 years+ - NCT05309395RecruitingPhase 3
Food prescriptions to help Latino families eat affordably
This trial tests whether giving free/covered “food prescriptions” helps multigenerational Latino households lose weight by improving diet within a budget. It may help families who want to eat healthier without worrying as much about grocery costs.
Pasadena, CaliforniaAges 2 years+ - NCT05530538Recruiting
Phone app program to help teens manage weight
This study tests a weight-management app (the BrainWeighve app) for teens. It looks at whether the app is workable and helpful for teens who are motivated to change weight habits.
Los Angeles, CaliforniaAges 14–21 - NCT06323070Recruiting
Watermelon vs. low-fat cookies for wellness
This trial compares eating watermelon or low-fat cookies to see how they affect your overall wellness. It will help determine if one snack is better for your health.
San Diego, CaliforniaAges 18–50 - NCT06570642Recruiting
Study on emotions and physical activity
This study looks at how emotions affect your desire to be active. You'll wear a Fitbit smartwatch and answer short surveys to help researchers understand what helps people start and stick with physical activity.
Los Angeles, CaliforniaAges 18 years+ - NCT06724172Recruiting
Comparing health programs for pregnant mothers from diverse backgrounds
This study tests two different health programs for pregnant women to see which one helps mothers and babies more. You may join if you are early in your pregnancy, identify as Black, Hispanic, or have Medicaid, and speak English or Spanish.
Palo Alto, CaliforniaAges 18 years+ - NCT06824974Recruiting
Time-restricted eating for liver disease or cancer
This study tests whether combining time-restricted eating with healthy eating helps people with metabolic liver disease, cirrhosis, or early-stage liver cancer. If you are overweight and currently fast less than 12 hours at night, this diet approach might improve your health.
La Jolla, CaliforniaAges 18 years+ - NCT06994338RecruitingPhase 2
Tirzepatide for alcohol use disorder
This study tests whether a medication called tirzepatide (a once-weekly injection) can help people reduce their alcohol consumption. It is for people who drink heavily, have a high BMI, and are actively seeking help to drink less.
Los Angeles, CaliforniaAges 21–65 - NCT07013643RecruitingPhase 1
How a new weight-loss drug affects birth control pills
This study checks if a new weight-loss medicine changes how the body handles birth control pills. It is for healthy women with overweight or obesity.
Glendale, CaliforniaAges 35–75 - NCT07044570Recruiting
Examining attitudes in physical activity engagement
This trial tests if a program can help people who are not very active start and stick with a physical activity routine. Participants will wear a study-provided smartwatch to track their activity and answer brief surveys.
Los Angeles, CaliforniaAges 18 years+
Obesity & Overweight trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting obesity & overweight studies listed above.
- Diablo Clinical Research · 2 studies
- Research Site · 2 studies
- University of Southern California · 2 studies
- ACCOMPLISH-1 Research Site
- Alarcon Urology Center
- Artemis Institute for Clinical Research
- Care Access
- CenExel ACT (Anaheim Clinical Trials)
What taking part in a obesity & overweight study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Obesity & Overweight trials in other states
Common questions
- Are there obesity & overweight clinical trials in California?
- Yes. We're currently tracking 64 recruiting obesity & overweight studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity & overweight study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity & overweight studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.