Clinical trials · California
Obesity & Overweight clinical trials in California
We’re tracking 64 recruiting obesity & overweight studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
San Diego, CaliforniaAges 18 years+ - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with overweight or obesity
This trial tests an investigational once-daily pill (ASC30) to see if it can help adults with overweight or obesity lose weight. You may be able to join if you have a high body mass index (BMI) and have tried to lose weight before.
Banning, CaliforniaAges 18 years+ - NCT06937086RecruitingPhase 3
Mirikizumab plus tirzepatide for UC with obesity
This study tests whether adding mirikizumab to the weight-loss drug tirzepatide helps people with moderate-to-severe ulcerative colitis who also have obesity or overweight. It aims to see if the combination reduces bowel inflammation and helps with weight management.
Anaheim, CaliforniaAges 18–70 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Escondido, CaliforniaAges 18–79 - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Escondido, CaliforniaAges 18–79 - NCT07497880RecruitingPhase 2
Study of a new pill for weight loss in adults with obesity
This trial tests a daily pill called KAI-7535 to see if it helps people with obesity or overweight lose weight safely. It is for adults who have a body mass index (BMI) of 27 or higher and at least one weight-related health problem, such as high blood pressure or type 2 diabetes.
Irvine, CaliforniaAges 18–75 - NCT07284875RecruitingPhase 3
Ribupatide for weight loss in adults without diabetes
This trial tests a new medication, Ribupatide, to see if it helps people with obesity or overweight who also have weight-related health problems. You cannot have diabetes to join.
Escondido, CaliforniaAges 18 years+ - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Los Angeles, CaliforniaAges 18 years+ - NCT06864026RecruitingPhase 4
Adding tirzepatide to ixekizumab for psoriatic arthritis with weight concerns
This study tests adding tirzepatide (a once-weekly injection for weight and diabetes) to your current treatment with ixekizumab for psoriatic arthritis. It may help with both joint symptoms and weight.
Apple Valley, CaliforniaAges 18 years+ - NCT07776678Recruiting
Body fat and muscle measurement study
This study uses advanced body scans (like MRI and DXA) to better measure body fat and muscle. It may help improve how obesity is diagnosed and treated.
Menlo Park, CaliforniaAges 18 years+ - NCT07090005Recruiting
Endoscopic weight loss: comparing EndoZip and Apollo ESG
This study compares two different endoscopic procedures (EndoZip and Apollo ESG) to help obese patients lose weight. Both are done through the mouth without cutting the skin, and the goal is to see which works better and is safer.
Los Angeles, CaliforniaAges 21–65 - NCT06067763Enrolling by invitation
Project Health: Preventing unhealthy weight gain in young adults
This study tests a program to help young adults improve their eating and exercise habits, with the goal of preventing obesity. It is designed for people who are concerned about their weight and want to make healthier lifestyle choices.
Stanford, CaliforniaAges 17–20 - NCT06924320RecruitingPhase 1/Phase 2
Study of two medicines for weight loss and diabetes
This study tests two investigational medications, MET233 and MET097, in people with obesity or overweight, with or without type 2 diabetes. It aims to see if the combination can help with weight loss and blood sugar control.
Cypress, CaliforniaAges 18–75 - NCT07511205RecruitingPhase 1
Study of AZD1043 for overweight or obesity
This trial tests a new medicine called AZD1043 in healthy adults who are overweight or have obesity. It aims to see if the medicine is safe and how the body handles it.
Glendale, CaliforniaAges 18–65 - NCT07392190RecruitingPhase 3
Study of eloralintide for people with persistent obesity
This trial tests if adding eloralintide helps people who are still obese or overweight while taking weekly incretin therapy. It aims to support additional weight loss for those who haven't reached their goals.
Irvine, CaliforniaAges 18 years+ - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
Escondido, CaliforniaAges 18 years+ - NCT07710768RecruitingPhase 1
A study on how UBT251 affects certain drugs in people with extra weight
This study tests if a new medicine called UBT251 changes how the body processes caffeine, midazolam (a sedative), and warfarin (a blood thinner). It is for generally healthy adults with a Body Mass Index (BMI) between 27 and 40.
Cypress, CaliforniaAges 18–65 - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Fountain Valley, CaliforniaAges 18–99 - NCT07253285RecruitingPhase 3
Study on cagrilintide and CagriSema for kids with excess weight
This trial tests two new medicines (cagrilintide and CagriSema) to see if they help children and teens lose weight. It's for young people who have tried lifestyle changes without enough success.
Escondido, CaliforniaAges 8–18 - NCT05143931Recruiting
Avoid and resist habits to manage weight
This study looks at strategies to help people manage their weight by changing how they respond to food-related cues and habits. It tests whether these approaches can be used over time with regular, brief check-ins.
Los Angeles, CaliforniaAges 14 years+ - NCT06891352Recruiting
Timing meals to reduce disease risk in night shift workers
This study tests whether adjusting when you eat (time-restricted eating) can improve health in night shift workers. You would use a smartphone app to track your meals and follow a set eating schedule for up to a year.
La Jolla, CaliforniaAges 18–70 - NCT07316816Recruiting
Weight loss study for teens with severe obesity
This study evaluates how continuous glucose monitors and other wearable devices can help teens in a bariatric program lose weight. You may join if you are in the program and ready for sleeve gastrectomy or GLP-1 medication.
Palo Alto, CaliforniaAges 10–18 - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07509307RecruitingPhase 3
Study of a new medicine for weight loss and knee pain in osteoarthritis
This trial tests if a new medicine, NNC0487-0111, can help people with excess weight and knee osteoarthritis lose weight and reduce knee pain. It is for people who have had knee pain for at least three months and who can stop taking pain relievers for short periods before study visits.
Escondido, CaliforniaAges 18 years+
Obesity & Overweight trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting obesity & overweight studies listed above.
- Research Site · 4 studies
- Artemis Institute for Clinical Research · 3 studies
- Cedars-Sinai Medical Center · 3 studies
- ACCOMPLISH Research Site · 2 studies
- ACCOMPLISH-1 Research Site · 2 studies
- Altasciences Clinical Los Angeles, Inc. · 2 studies
- Diablo Clinical Research · 2 studies
- Kailera Clinical Site · 2 studies
What taking part in a obesity & overweight study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Obesity & Overweight trials in other states
Common questions
- Are there obesity & overweight clinical trials in California?
- Yes. We're currently tracking 64 recruiting obesity & overweight studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity & overweight study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity & overweight studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.