Clinical trials
Older Patients clinical trials
Below are recruiting older patients clinical trials, each written for real people, not researchers. We’re tracking 127 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07740694Recruiting
ECT study for older adults with depression
This study looks at how ECT affects brain activity and inflammation in older adults with depression. It may help researchers understand why ECT works and improve treatment.
Istanbul, BakırköyAges 55 years+ - NCT07463586Recruiting
Brain oxygen and confusion after surgery in older adults
This study looks at how giving extra oxygen during surgery affects brain function and confusion (delirium) in older adults. It involves placing a small sensor on your forehead to measure brain oxygen levels.
Seongnam-si, Gyeonggi-doAges 65 years+ - NCT07369596Recruiting
Chemotherapy doses and survival in older lung cancer patients
This study looks at how lowering chemotherapy doses affects survival in older patients with advanced lung cancer who do not have certain genetic mutations. It may help doctors understand the best way to treat this group.
Hong KongAges 65 years+ - NCT07300995Recruiting
Pain coping skills for older women with breast cancer
This study tests a behavioral program to help older women with breast cancer learn skills to cope with pain. The program is done through video or phone sessions.
Durham, North CarolinaAges 55 years+ - NCT06893419Recruiting
Telehealth for nursing home residents after hospital stay
This trial tests a telehealth program to help nursing home residents manage their health after a recent hospital stay. It may improve your recovery and keep you healthier.
AnconaAges 70 years+ - NCT06835530RecruitingPhase 2
Rituximab and CC-99282 for older frail patients with large b-cell lymphoma
This trial tests a combination of two drugs, rituximab and CC-99282, as a first treatment for older adults with diffuse large b-cell lymphoma who are too frail for standard chemotherapy. The goal is to see if this gentler approach can effectively control the disease while being easier to tolerate.
Alessandria, AlessandriaAges 80 years+ - NCT06375265Recruiting
Sleep improvement program for older surgery patients
This trial tests a digital sleep improvement program for older adults who are about to have knee or hip replacement surgery. It aims to help you sleep better before and after surgery, which may improve your brain health and recovery.
Boston, MassachusettsAges 65 years+ - NCT05336565Recruiting
COVID-era heart illness patterns in adults with cardiovascular disease
This study looks at how often heart problems happened in adults with cardiovascular disease during the COVID-19 pandemic period. It may help researchers understand what factors during the pandemic affected heart health.
TomskAges 18 years+ - NCT04452825Recruiting
Psychotherapy for older adults with cancer distress
This trial studies a new talking-therapy program for people age 70+ who have cancer and feel emotional distress. It may help reduce anxiety and low mood while you’re receiving cancer treatment or followed closely after treatment.
New York, New YorkAges 70 years+ - NCT04164940Recruiting
Tracking how hospital care affects alcohol risk in older adults
This study looks at how adults aged 21+ change over time after being admitted to the hospital for alcohol-related problems. It may help researchers understand which hospital approaches work best for reducing future alcohol-related harm—especially for people who have not had alcohol or drug use disorders before.
StavangerAges 21 years+ - NCT07610161Recruiting
Living Alone With a Limb Injury: A 12-Week Study
This study explores how older adults who live alone manage daily life after a limb injury. Researchers want to understand your experience and challenges over 12 weeks to help improve support for people in similar situations.
Kaohsiung City, KaohsiungAges 65–74 - NCT07442656Recruiting
Frailty and outcomes in older adults with pneumonia
This study looks at how frailty (overall weakness and decline) affects recovery in older adults who come to the emergency room with pneumonia. The goal is to understand what outcomes patients can expect based on their frailty level.
Izmir, BornovaAges 65 years+ - NCT06655272RecruitingPhase 4
OM 85 to prevent lung infections in older nursing home residents
This study tests a medication called OM 85 that may help prevent respiratory infections (like pneumonia) in older adults living in nursing homes. If you are 75 or older and have had infections recently, this trial could be a way to stay healthier.
Roma, RMAges 75 years+ - NCT07273357Recruiting
CDK4/6 inhibitors for older breast cancer patients
This study looks at how well older breast cancer patients (70 years and older) do when treated with a type of drug called a CDK4/6 inhibitor along with hormone therapy after surgery. The goal is to use simple health checks to help doctors decide if this treatment is right for you.
GävleAges 70 years+ - NCT07020065RecruitingPhase 2
Reduced chemo plus immunotherapy vs immunotherapy alone for older lung cancer patients
This trial tests whether a reduced dose of chemotherapy plus an immunotherapy drug (Cemiplimab) works better than Cemiplimab alone for older or frail patients with advanced lung cancer whose PD-L1 level is below 50%. It aims to find a gentler but effective treatment option.
Fribourg, Villars-sur-GlâneAges 70 years+ - NCT04959175RecruitingPhase 1/Phase 2
Lower-dose transplant drug for older or frail patients with blood cancer
This study tests whether a lower dose of a drug used after bone marrow transplant can reduce side effects while still preventing graft-versus-host disease (a condition where donor cells attack the patient's body). It is for older patients or those who are not healthy enough for a standard, stronger conditioning regimen.
Bethesda, MarylandAges 12–85 - NCT04913649RecruitingPhase 4
IV iron for anemia after heart surgery in older adults
This trial tests whether giving iron through a vein after heart surgery helps treat postoperative anemia (low red blood cells) in people age 70 and older. It may improve recovery by correcting low iron levels after surgery.
BredaAges 70 years+ - NCT03451383Recruiting
Study brain changes in older breast cancer patients
This study follows older women with newly diagnosed breast cancer to see who might develop thinking or memory problems over time. It may help researchers understand early brain risk and how treatment and other factors relate to cognitive decline.
Washington D.C., District of ColumbiaAges 60–105 - NCT07677319Recruiting
Heart surgery after age 75: a study on recovery
This study looks at how well people aged 75 and older recover after emergency heart surgery. It uses a special test to measure frailty and quality of life for one year after surgery.
Bordeaux, FranceAges 75 years+ - NCT07514169RecruitingPhase 2
New Combination Drug for Older Adults with B-Cell Lymphoma
This study tests whether a new three-drug combination (Pola-ZR-Glo) works safely and effectively for older adults with a type of blood cancer called large B-cell lymphoma who cannot or prefer not to receive standard chemotherapy. The goal is to find a gentler treatment option for frail or elderly patients.
ShanghaiAges 70 years+ - NCT07421713Recruiting
AI and chest x-rays to screen for osteoporosis
This trial tests if an AI software can use a chest x-ray to screen for osteoporosis, compared to the standard DXA bone density scan. It may offer a faster, simpler way to check bone health in people 50 and older.
RotterdamAges 50 years+ - NCT07366684Recruiting
Heart attack study for adults 75 and older
This study looks at how frailty and other health factors affect recovery in people 75 and older who have had a heart attack or unstable chest pain. It may help doctors better understand who is at higher risk and how to improve care for older adults.
NišAges 75 years+ - NCT06931067Recruiting
Exercise program to prevent falls in older adults
This study tests an exercise program called OTAGO, combined with motivational interviewing, to help older adults at high risk for falling improve their balance and strength. If you are 60 or older, have had a fall or worry about falling, and have some difficulty walking or moving around, this trial may be a good fit for you.
Portland, OregonAges 60–120 - NCT06972537Recruiting
Piperacillin-Tazobactam Dosing for Pneumonia in Older Adults
This study looks at the best way to give the antibiotic piperacillin-tazobactam (Zosyn) to people 65 and older who have pneumonia. It aims to make treatment more effective and safer for older adults.
Jinan, ShandongAges 65–100
Hear when a new Older Patients trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for older patients?
- Yes. Clin2 currently lists 127 recruiting older patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a older patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a older patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.