Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 611 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07533188Recruiting
Robotic Knee Replacement Surgery Alignment Techniques Study
This study compares two different ways surgeons can align and position a robotic knee replacement to see which gives better results. You'll be randomly assigned to one approach and tracked over time to measure pain, function, and satisfaction.
SingaporeAges 18 years+ - NCT07556003Recruiting
Physical Therapy After Knee Replacement Surgery
This study tests whether a physical therapy program helps improve walking ability and foot pressure patterns in women who have had knee replacement surgery or have knee problems. The goal is to see if structured rehabilitation helps you walk better and more comfortably.
SakakahAges 40–70 - NCT07558590Recruiting
Shoulder Replacement System Recovery and Function Study
This study follows patients who have received a new shoulder replacement device to see how well it works and how patients recover. Researchers will collect information about your shoulder function and satisfaction over time.
AmiensAges 18 years+ - NCT07566507Recruiting
High-Energy Laser for Thumb Joint Arthritis
This trial tests whether a high-energy laser can reduce pain and improve function in people with arthritis at the base of the thumb (where it connects to the wrist). The laser is applied to the skin and may help by reducing inflammation and pain without surgery.
BariAges 18 years+ - NCT07574762Recruiting
Knee Replacement: Computer Navigation vs. Robotic Surgery
This study compares two advanced surgical techniques for knee replacement in patients with knee arthritis. Researchers want to see if robotic-assisted surgery offers any advantages over computer-guided navigation surgery for placing the artificial knee.
Paris, ParisAges 18 years+ - NCT07595718Recruiting
AI Study of Disease Patterns and Health Data
This research uses artificial intelligence to analyze health information from adults to better understand and predict when major diseases like diabetes, heart disease, and cancer might develop. Your participation could help scientists discover new patterns that improve early detection.
Seoul, Seoul Special CityAges 30–60 - NCT07618403Recruiting
Physical Therapy for Knee Arthritis
This study tests whether a structured physical therapy program helps knee arthritis pain and function. Researchers will also look at how your expectations about treatment affect your results.
Ankara, YenimahalleAges 50 years+ - NCT07630337Recruiting
Cryotherapy to reduce pain medication after knee replacement
This study tests whether applying cold therapy (cryotherapy) after knee replacement surgery helps patients need fewer opioid pain medications than standard care alone. If cryotherapy works, it could help you manage pain more safely after surgery.
Buenos Aires, Buenos AiresAges 18 years+ - NCT07645989Recruiting
Registry tracking long-term outcomes after MuseCell treatment
This registry follows patients who have received Dezawa MuseCells (a type of cell therapy) to understand how well the treatment works over 5 years. You'll complete online surveys about your health and progress periodically.
North Palm Beach, FloridaAges Up to 89 years - NCT07651462Recruiting
Fasting Before Hip Surgery and Gut Health
This study tests whether fasting for 20 days before hip replacement surgery changes your gut bacteria in ways that might help your recovery. Researchers want to understand if this dietary approach affects how well you heal after the operation.
Berlin, State of BerlinAges 18–75 - NCT07651735Recruiting
Safety and Recovery Study of Tipmed Hip Replacement
This study tracks how well people recover after hip replacement surgery using the Tipmed hip implant system. Researchers will monitor your healing and implant performance over time to ensure the device works safely and effectively.
BalıkesirAges 18 years+ - NCT07652437Recruiting
Wearable device study for knee osteoarthritis walking
This study tests whether a wearable device can help people with knee osteoarthritis walk more easily and for longer periods. If you have knee pain or stiffness on most days and find walking difficult, this might help you improve your mobility.
Cambridge, MassachusettsAges 21–100 - NCT07478861Enrolling by invitation
Vibration training for seniors with knee arthritis and obesity
This study tests whether whole-body vibration training can help older adults who have both severe knee arthritis and obesity. It aims to improve strength, mobility, and quality of life.
Banī SuwayfAges 60–75 - NCT07351981Enrolling by invitation
Cooled radiofrequency for knee osteoarthritis pain
This study tests a new approach called cooled radiofrequency (TcPRF) to calm knee pain from osteoarthritis. It may be an option if standard treatments haven't worked and you haven't had certain other treatments recently.
AthensAges 45 years+ - NCT07255768Enrolling by invitation
Pain relief blocks for hip surgery: comparing two methods
This study compares two types of nerve blocks to see which provides better pain relief after hip surgery. One block targets the capsule around the hip joint, while the other adds blocks for nearby nerves. The goal is to find a more effective way to manage pain.
ErzurumAges 18–80 - NCT07219888Enrolling by invitationPhase 4
Comparing suzetrigine and oxycodone for knee replacement pain
This study compares a new pain medicine called suzetrigine with a commonly used opioid, oxycodone, for pain after a knee replacement. The goal is to see which works better and has fewer side effects.
Louisville, KentuckyAges 21–89 - NCT07150221Enrolling by invitation
10-year follow-up of vitamin E hip liner
This study follows people who received a special vitamin E infused plastic hip liner (Vivacit-E) during a first-time total hip replacement about 10 years ago. It checks how the implant is holding up over time.
South Bend, IndianaAges 18 years+ - NCT07047079Enrolling by invitation
Pre-surgery exercise program for knee replacement patients
This trial tests a patient-navigation-based exercise program for people scheduled for knee replacement surgery. The goal is to see if doing exercises before surgery helps with recovery.
Guangzhou, GuangdongAges 45–90 - NCT06988163Enrolling by invitation
Osteoarthritis care tools for primary care doctors
This study tests a tool to help doctors manage osteoarthritis care. You may join if you are a healthcare provider at the UNC pilot clinic or a patient who has been referred to the 'Walk With Ease' program by that clinic, are 18 or older, and speak English.
Chapel Hill, North CarolinaAges 18–99 - NCT06911437Enrolling by invitation
Knee pain relief with Chinese formula and massage
This study tests if combining a Chinese herbal formula called Xiaoyu Zhitong with a gentle drainage massage can reduce knee pain and swelling. It may help people whose knee symptoms are worse in cold, damp weather.
BeijingAges 25–70 - NCT06892899Enrolling by invitation
Exercise study for knee health after ACL surgery
This study tests whether a specific exercise program can improve knee health in people who have had ACL surgery. It aims to understand how exercise affects the knee after injury and may help prevent arthritis.
Oslo, OsloAges 16–40 - NCT06885372Enrolling by invitation
Long-term follow-up of ACL tear patients without surgery
This trial is for people with a torn ACL who are young (up to 25) and have certain risk factors for knee instability. It will follow them long-term to see how their knee does without surgery, focusing on those who are active in pivoting sports, have a loose knee joint, or have naturally loose joints.
Banff, AlbertaAges 14–25 - NCT06670651Enrolling by invitation
Study of a new total knee replacement system
This trial is testing a new knee replacement system called LinkSymphoKnee. It is for people needing a first-time total knee replacement to help reduce pain and improve function.
Birmingham, AlabamaAges 18–79 - NCT06623149Enrolling by invitation
Surgery vs. non-surgery for knee arthritis
This study compares non-surgical treatments with knee replacement surgery for people with knee osteoarthritis. It aims to find out which approach works better.
Copenhagen, CopenhagenAges Any age
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 611 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.