Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 591 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04660955Enrolling by invitation
10-year follow-up MRI after ACL surgery in young athletes
This study uses an MRI scan to look at knees 10 years after ACL reconstruction. It helps researchers understand how the knee changes over time after sports-related ACL injury, and how well reconstruction lasts.
Cleveland, OhioAges 22–45 - NCT04536103Recruiting
Accelerated MRI scans after ACL knee injury surgery
This trial tests a faster MRI scan method to measure healing in the knee after an ACL (anterior cruciate ligament) tear and reconstruction. It may help researchers compare scan quality while participants go through standard rehab.
Cleveland, OhioAges 18–50 - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT04449146Recruiting
Ultrasound guide for shoulder position during standing test
This study uses ultrasound (a non-radiation imaging tool) to help check the best way to hold your shoulder blade while standing. It’s aimed at people having a reverse shoulder replacement on their own shoulder joint, to see if this positioning method can improve care or planning.
BrestAges 18–99 - NCT04458584Recruiting
Thumb surgery trial comparing treatments for basal joint arthritis
This study looks at how well different thumb (basal joint) surgery approaches restore strength and function. You would be having planned (non-replacement) thumb surgery, and your chosen surgeon would care for you while researchers compare outcomes.
Lebanon, New HampshireAges 21 years+ - NCT04145401Enrolling by invitation
Long-term follow-up for a specific knee revision implant
This study tracks how well a particular knee revision implant performs over many years. It may help you by closely monitoring your knee after revision surgery and adding to long-term safety and performance data.
Englewood, ColoradoAges 21 years+ - NCT03968913RecruitingEarly Phase 1
Biologic shot to prevent knee arthritis after ACL injury
This early-phase trial tests a biologic medicine (anakinra) given after an ACL injury to try to prevent or reduce later osteoarthritis (wear-and-tear arthritis). It enrolls young adults who recently tore their ACL and are planning a specific type of ACL reconstruction.
Los Angeles, CaliforniaAges 18–35 - NCT03921944Recruiting
CT and nerve tests after shoulder replacement for arthritis
This study checks how well the rotator cuff (the shoulder’s key tendons/muscles) is working after a total shoulder replacement done for arthritis. It uses CT scans and nerve testing to see what affects shoulder structure and function, which may help improve future care.
Hershey, PennsylvaniaAges 45 years+ - NCT03804853Recruiting
Rehab program after reverse shoulder replacement surgery
This trial studies a rehabilitation plan after reverse total shoulder arthroplasty (reverse shoulder replacement) to see if it improves recovery. If you are eligible, you may be guided through specific therapy and follow-up visits as part of the study.
Bloomington, MinnesotaAges 55 years+ - NCT03869996Recruiting
Fast-track recovery for knee replacement patients
This trial studies a faster recovery “fast-track” plan for people getting their first total knee replacement for arthritis. It may help by getting you back to movement and normal life sooner, while comparing outcomes against usual care.
BolognaAges 18–78 - NCT03404778Enrolling by invitation
Collecting data on reverse shoulder implants for weak rotator cuff
This study collects real-world information about a reverse shoulder implant used when the rotator cuff is badly damaged. It may help improve how these implants are chosen and how well they work for pain relief and improving arm function.
Towson, MarylandAges 18 years+ - NCT03304730Recruiting
Tracking pain patterns after low back joint injections
This study follows adults with long-lasting low back pain to learn what predicts who improves after a specific type of back joint injection. It mainly helps doctors understand which factors relate to better or worse outcomes over time.
São Paulo, São PauloAges 18 years+ - NCT02836262Recruiting
New hip replacement implant for painful worn-out hip joints
This trial studies a specific hip replacement implant system in people whose hip pain is from worn-out (non-inflammatory) joint disease like osteoarthritis. It compares outcomes by tracking pain and function before and after surgery, and you must be able to return for follow-up visits.
Winnipeg, ManitobaAges 65–79 - NCT02993029Recruiting
Fluoride scan–guided treatment for painful knee arthritis
This trial studies a targeted treatment using a fluoride-related injection to help reduce pain from knee osteoarthritis. To join, you need a painful osteoarthritis knee and a specific bone-scan finding (SUV above 10) on an imaging test.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT00411060Recruiting
Orthopaedic data bank study for acute and chronic problems
This study collects information about orthopedic (bone, joint, muscle) problems from people seen in the orthopaedics clinic. It may help improve future care by organizing real-world clinical data.
Gainesville, FloridaAges Any age
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 591 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.