Clinical trials
Paediatrics clinical trials
Below are recruiting paediatrics clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04873583RecruitingPhase 3
High-dose steroids for children after a one-sided stroke
This trial tests whether high-dose steroids given soon after a stroke can improve outcomes for children. It is aimed at children whose stroke is caused by a one-sided blood-vessel problem seen on brain scans.
Randwick, New South WalesAges 6 months–17 years - NCT05017363Recruiting
Child goal-setting coaching during rehab therapy
This study tests whether a child-friendly goal-setting approach helps kids do better during physical therapy or occupational therapy. It may help children and families set clearer goals and feel more motivated during rehab.
Edmonton, AlbertaAges 5–12 - NCT05198570Recruiting
Measuring how acyclovir moves in children with cancer
This study checks how acyclovir behaves in the body when it’s given by mouth or through an IV to children receiving cancer care. It may help doctors better choose doses and monitor the medicine in kids who need prevention or treatment of certain viral infections.
Trieste, TSAges 6 months–18 years - NCT05224193Recruiting
Study of exercise and sleep in kids with inflammatory bowel disease
This study looks at how physical activity and sleep habits affect children and teens with inflammatory bowel disease. It may help doctors understand which routines could support better day-to-day health and disease management.
Southampton, HampshireAges 6–18 - NCT05553899Recruiting
PET-MRI scans for monitoring children’s brain tumor return
This study checks whether a special scan called PET-MRI can better tell if a child’s brain tumor has come back after treatment. It may help doctors decide faster and more accurately when changes seen on regular MRI are true tumor recurrence.
Sheffield, South YorkshireAges 8–18 - NCT05555771Recruiting
Kids with fainting episodes after arriving at the emergency room
This study looks at children and teens (ages 6–18) who recently fainted but are now back to normal, using a survey. It aims to better understand fainting episodes that happen before the emergency visit and how to evaluate them safely.
Vancouver, British ColumbiaAges 6–18 - NCT05615389RecruitingPhase 1/Phase 2
Medicinal cannabis pilot for children’s distress symptoms
This early-phase study tests medicinal cannabis to help improve symptoms like pain, muscle stiffness (dystonia), and gut problems in children who are receiving palliative care for non-cancer conditions. You may be asked to follow a medication schedule and not start or change other treatments right before joining.
Parkville, VictoriaAges 6 months–21 years - NCT05673096Recruiting
PACT therapy for young autistic children and their parents
This trial studies a structured communication therapy program (PACT) for children ages 2–6 who have autism. It aims to improve how children communicate and how families can support communication at home.
AabenraaAges 2–6 - NCT05748717Recruiting
Tests blood flow in children with sickle cell
This study measures how well blood flows through brain arteries in children with sickle cell disease using a noninvasive ultrasound test. It may help doctors better understand stroke risk and how treatments like hydroxyurea or recent care affect blood flow.
Kingston, Saint Andrew ParishAges 4–16 - NCT05770037RecruitingPhase 2/Phase 3
Alectinib for ALK-positive cancers in teens and adults
This study tests whether alectinib can treat ALK-positive cancers in adults, teenagers, and children. It focuses on people whose cancer testing shows an ALK change, and who can start oral treatment and have a new tissue sample.
BelfastAges Any age - NCT05770102RecruitingPhase 2/Phase 3
Atezolizumab for cancers with high mutation or immune markers
This trial tests atezolizumab, a cancer immunotherapy, for people whose tumors have high mutation levels (TMB), or are “MSI-high,” or have CMMRD. It may help shrink cancer or slow its growth by boosting the immune system’s ability to recognize the tumor.
BelfastAges Any age - NCT05770544RecruitingPhase 2/Phase 3
Entrectinib for ROS1 fusion cancers with matching gene test
This trial studies entrectinib, a targeted pill, in people whose cancer has a specific gene change called ROS1 fusion. It may help by shrinking tumors that depend on this ROS1 gene switch, and the study requires starting with a new tissue sample and treatment monitoring.
BelfastAges Any age - NCT05781295Recruiting
Taurolidine vs saline lock for kids’ central line
This trial studies whether a medicine lock called taurolidine is safer or works better than a standard saline (salt water) lock for pediatric cancer patients with central venous lines. It’s meant to help prevent central-line infections.
ParisAges Up to 21 years - NCT05786716RecruitingPhase 2/Phase 3
Trastuzumab plus pertuzumab for HER2-mutated cancers
This trial tests whether combining trastuzumab and pertuzumab can treat cancers that have HER2 amplification or an activating HER2 mutation. It looks at people ages 12 and older, and may include both children/teens and adults, using the study drug based on their HER2 test results.
BelfastAges 12 years+ - NCT05891873Recruiting
Study delirium during ICU care for stroke patients
This study looks at “delirium,” a sudden confusion that can happen during critical care, in people receiving ICU treatment for stroke. It includes both adults and children in specific ICU settings and may help clinicians better prevent or manage confusion during recovery.
BrnoAges Any age - NCT05982847Recruiting
Blood pressure check for kids in South Africa
This study checks blood pressure in children ages 5 to 17 across South Africa. It aims to find normal blood pressure ranges and improve healthcare for kids.
Mthatha, Eastern CapeAges 5–18 - NCT05991388RecruitingPhase 2/Phase 3
New treatments for children with relapsed B-NHL
This trial tests two new treatment combinations for children and young adults with B-cell non-Hodgkin lymphoma that has come back or not responded to previous therapy. The goal is to find better options for treating this cancer.
Sydney, New South WalesAges Up to 25 years - NCT06190431Recruiting
Can coaching help kids learn to use a lung-clearing device?
This study tests whether a coaching feature helps children learn to use a device called mechanical in-exsufflation (MI-E), which helps clear mucus from the lungs. The trial is split into two parts: one for healthy children and one for children with neuromuscular diseases.
Brussels, Brussels CapitalAges 6–12 - NCT06212362Recruiting
Comparing two talk therapies for anxious kids aged 7-12
This trial compares two kinds of therapy for children with mild to moderate anxiety. It tests whether a stepped care approach works as well as group cognitive behavioral therapy (CBT) to help reduce anxiety.
SolnaAges 7–12 - NCT06292299Recruiting
Breathing monitor study for children with sleep or breathing issues
This study looks at how well a new breathing monitor works for children with sleep problems, breathing pauses in newborns, or epilepsy. It may help doctors better understand breathing patterns without extra needles or blood tests.
Glasgow, Glasgow CityAges 1 minute–16 years - NCT06315556Recruiting
Study of Eylea for preterm babies with retinopathy of prematurity in the UK
This study collects information on how the medicine Eylea is given to preterm babies with retinopathy of prematurity (an eye problem in premature infants) using a special dosing device. The goal is to see how the treatment works in everyday hospital care.
Multiple LocationsAges Up to 1 year - NCT06383338RecruitingPhase 1
Metabolism Changes in Young People with Lymphoma
This study looks at how your body's metabolism (processing of food and medicine) changes after you start treatment for lymphoma. It uses two safe, commonly used drugs (omeprazole and dextromethorphan) to measure these changes.
Melbourne, VictoriaAges 6–25 - NCT06457412Recruiting
Program for Helping Children with Severe Obesity
This study tests a program designed to help children ages 6 to 12 with severe obesity. It focuses on lifestyle changes like healthy eating and physical activity to improve your child's health.
CórdobaAges 6–12 - NCT06599879Recruiting
Brain radiation effects on memory and attention in kids
This study looks at how radiation from brain tumor treatment affects memory, attention, and thinking skills in children. It uses brain scans and tests to understand these effects.
AngersAges 6–14
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Common questions
- Are there clinical trials for paediatrics?
- Yes. Clin2 currently lists 97 recruiting paediatrics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a paediatrics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a paediatrics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.