Clinical trials
Postoperative Pain Management in Total Knee Arthroplasty clinical trials
Below are recruiting postoperative pain management in total knee arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 9 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07286513Enrolling by invitation
Study of a new knee replacement implant
This study follows patients who receive a specific type of knee replacement implant called the Persona® SoluTion® PPS, to see how well it works over time. If your surgeon recommends this implant and you meet standard health requirements, you may be able to join.
Denver, ColoradoAges 18 years+ - NCT06557018RecruitingPhase 4
Numbing medicine injection for knee replacement pain
This study tests a long-lasting numbing medicine (liposomal bupivacaine) injected around the knee during total knee replacement surgery. It aims to see if this medicine helps control pain and reduce the need for other painkillers after surgery.
Dezhou, ShandongAges 18–80 - NCT06600815Recruiting
Step-by-step numbing shots for pain relief in knee replacement
This study tests whether a special step-by-step numbing injection given before knee replacement surgery can provide better pain relief during and after the procedure. It may help you have less pain and use fewer painkillers after surgery.
Fuzhou, FujianAges 18 years+ - NCT07242170Recruiting
Comparing nerve blocks for pain after knee replacement surgery
This trial tests if adding extra nerve blocks (sciatic, BiFeS, or IPACK) to the usual adductor canal block can reduce pain after total knee replacement. The goal is to find a better way to manage pain and improve recovery.
Erzincan, MerkezAges 18–75 - NCT07248072Recruiting
Nerve blocks for better recovery after knee replacement
This trial tests two types of nerve blocks—iPACK and BiFeS—to see if they help people feel better and recover faster after total knee replacement surgery. It compares adding these blocks to the usual spinal anesthesia.
ErzurumAges 18–75 - NCT07524387Recruiting
Nerve blocks for better leg strength after knee replacement
This study compares two types of numbing injections (nerve blocks) used during knee replacement surgery to see which one helps your thigh muscle recover strength faster. Both are standard care options; the trial tests which works better for early movement after surgery.
Ichinomiya, Aichi-kenAges 20 years+ - NCT07362589Enrolling by invitation
Does pain education before knee or hip replacement help?
This study tests whether a special education session before knee or hip replacement surgery can help reduce anxiety, pain, and the need for pain medicine after surgery. If you are scheduled for joint replacement and can take part in a short learning session, you may be eligible.
Istanbul, KayişdağiAges 18 years+ - NCT06574269RecruitingPhase 2
Study on TLC590 for pain after surgery
This trial tests a new pain medicine, TLC590, for people having one of several common surgeries, like bunion removal, hernia repair, breast augmentation, knee replacement, or tummy tuck. The goal is to see if it helps manage pain after the procedure.
Bellaire, TexasAges 18–70 - NCT04811209Recruiting
Testing better pain control and recovery after orthopedic surgery
This trial looks at how well a pain-control plan works after certain orthopedic surgeries and how it affects recovery and patient-reported outcomes. It may help determine what level of pain relief is meaningful to patients after surgery.
Toronto, OntarioAges 18–80
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Common questions
- Are there clinical trials for postoperative pain management in total knee arthroplasty?
- Yes. Clin2 currently lists 9 recruiting postoperative pain management in total knee arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain management in total knee arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain management in total knee arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.