Clinical trials
Pain Management clinical trials
Below are recruiting pain management clinical trials, each written for real people, not researchers. We’re tracking 338 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06353529RecruitingPhase 4
Pain management after pituitary tumor surgery
This study tests a nerve block (called sphenopalatine ganglion block) for pain relief after pituitary tumor surgery through the nose. It aims to see if this block helps manage pain and reduces the need for other pain medicines.
Hamilton, OntarioAges 18–100 - NCT07750626Recruiting
Vibration and ShotBlocker for injection pain in children
This study tests two methods to reduce pain and fear during a shot in the emergency department. It compares using a vibration device or a ShotBlocker device against standard care.
BurdurAges 5–10 - NCT07755540RecruitingPhase 2
Group music therapy for chronic pain in active duty service members
This study tests whether participating in group music therapy sessions can help active duty service members manage chronic pain. It aims to see if music therapy can improve pain symptoms and quality of life.
Anchorage, AlaskaAges 18–64 - NCT07429916RecruitingEarly Phase 1
Ketamine for shoulder pain after weight loss surgery
This trial tests if a single dose of ketamine, given during surgery, can reduce common shoulder pain after laparoscopic gastric sleeve surgery. If you are having this weight-loss procedure and meet the weight and health criteria, this study may help improve your recovery.
IrbidAges 18–60 - NCT06502457Recruiting
Virtual reality hypnosis for labor pain
This study tests whether using a virtual reality hypnosis program can help manage pain during early labor in women with low-risk pregnancies. If you are in the beginning stages of labor and want a non-drug option for comfort, this might be for you.
AmiensAges 18 years+ - NCT06515691Recruiting
Nerve block for pain after weight loss surgery
This study tests a nerve block (an injection near the nerves) to see if it helps reduce pain after laparoscopic sleeve gastrectomy. The block is called a modified thoracoabdominal nerve plane block, and it may lead to better pain control and recovery.
Istanbul, BagcilarAges 18–65 - NCT04130464RecruitingPhase 4
Analgesic placed inside the belly for after-surgery pain
This study tests whether placing a pain medicine inside the abdomen during hysterectomy can reduce postoperative pain. It targets people having specific types of minimally invasive hysterectomy for non-cancer reasons.
Washington D.C., District of ColumbiaAges 18–65 - NCT07452627Recruiting
Comparing Nerve Blocks for Sternotomy Pain
This study compares three different injection techniques (nerve blocks) to reduce pain after heart surgery that cuts through the breastbone. The goal is to find the best way to control pain with fewer side effects.
Bursa, NilüferAges 18–80 - NCT06932406Recruiting
Personality and self-help for jaw pain
This study tests whether a self-management program for jaw and face pain works differently in people with different personalities. You will learn techniques to manage your pain at home.
Valencia, ValenciaAges 18–65 - NCT07158476RecruitingPhase 4
Steroid injection for pain after ACL repair
This trial tests whether a single dose of methylprednisolone (a steroid) can reduce pain after ACL knee surgery. You will be randomly assigned to receive either the steroid or a placebo, and your pain levels will be tracked.
St Louis, MissouriAges 13–50 - NCT05266040RecruitingPhase 2
Valacyclovir to reduce pain from infected tooth abscess
This Phase 2 study tests whether valacyclovir, an antiviral medicine, can help reduce moderate-to-severe pain from an acute infected tooth abscess. Participants also receive standard dental treatment, and the study looks at whether the added medicine helps with pain.
San Francisco, CaliforniaAges 18–80 - NCT06946290Recruiting
Nerve block for pain relief after heart surgery
This study tests a nerve block, called an intertransverse process block, to see if it helps people feel better and recover faster after heart surgery. The block is given during surgery to reduce pain.
Hong KongAges 18 years+ - NCT06797973RecruitingPhase 4
Morphine for pain after planned cesarean section
This trial studies whether giving a small dose of morphine into the spinal fluid during a planned cesarean section helps with pain after surgery. It aims to find a safe and effective way to manage pain for new mothers.
AarhusAges 18 years+ - NCT06327542Recruiting
Group pain management in primary care clinics
This trial tests a group-based program to help people with chronic pain manage their symptoms. It is offered in primary care clinics that serve underinsured communities, and sessions are available in English or Spanish.
San Francisco, CaliforniaAges 18 years+ - NCT04166877RecruitingPhase 4
Magnesium drip to reduce pain in ICU trauma patients
This trial tests whether a magnesium infusion can better control pain in adults who have serious injuries and need intensive care. It compares magnesium as part of pain treatment to standard pain care to see if pain improves and stays controlled.
Sacramento, CaliforniaAges 18 years+ - NCT05916235Recruiting
Laser light treatment for jaw pain from TMJ disorder
This trial tests whether a specific type of light therapy (called photobiomodulation/laser) can reduce pain from temporomandibular disorder (TMJ) affecting the jaw muscles. If you have jaw muscle pain for at least 3 months, the study will compare your symptoms while you follow the treatment and diary requirements.
Gainesville, FloridaAges 18–99 - NCT07369024RecruitingPhase 2
Study of low-dose ketamine for sickle cell pain crisis
This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.
Torrance, CaliforniaAges 5–20 - NCT07824908Recruiting
Numbing medicine and pain after keyhole appendix removal
This study looks at whether the place where the appendix is taken out during keyhole surgery and the use of numbing medicine can help reduce pain after the operation. If you're having this emergency surgery, you may have less pain afterward.
Diyarbakır, KayapınarAges 18 years+ - NCT07770191Recruiting
Distraction methods for easing pain and fear during blood draws in children
This study tests different distraction techniques, like chewing gum or other activities, to help reduce pain and fear when children aged 5 to 10 get blood drawn. The goal is to make the experience more comfortable and less stressful.
TekirdağAges 5–10 - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07311369RecruitingPhase 2
Testing a new pain tablet after abdominal surgery
This trial tests a new pain tablet (HL-1186) for people having abdominal surgery. It aims to see if the tablet is safe and works well to manage pain after the operation.
Changsha, HunanAges 18–75 - NCT07085065Recruiting
Virtual reality for pain and anxiety during blood cancer procedures
This trial tests whether watching a virtual reality experience during a medical procedure can help reduce pain and anxiety for people with blood cancers. You may be able to take part if you are getting a bone marrow biopsy, spinal tap, blood draw, or chemotherapy.
Tunis, Sfax GovernorateAges 6 years+ - NCT06819956RecruitingPhase 3
Lower-dose ketorolac for pain in the ICU
This trial tests whether a lower dose of the pain medicine ketorolac can safely control pain for people in the intensive care unit (ICU). If you are in the ICU and have pain, this study might help find a better way to treat it.
Edmonton, AlbertaAges 18 years+ - NCT06725550Recruiting
Acupuncture for pain in sickle cell disease
This trial tests whether adding acupuncture to standard pain treatments can help manage pain in people with sickle cell disease. It involves brain scans, questionnaires, and acupuncture sessions to see if this approach reduces pain and improves quality of life.
Cincinnati, OhioAges 14–80
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Common questions
- Are there clinical trials for pain management?
- Yes. Clin2 currently lists 338 recruiting pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.