Clinical trials
Pain Management clinical trials
Below are recruiting pain management clinical trials, each written for real people, not researchers. We’re tracking 349 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07092605Enrolling by invitationEarly Phase 1
Microdosed semaglutide for longer, healthier life
This trial tests whether a very low ('micro') dose of semaglutide can improve health, quality of life, and how long you live well. It's for people who are interested in the drug's general health benefits but not specifically for weight loss.
Ann Arbor, MichiganAges 18–65 - NCT07275710Recruiting
Alprazolam for tooth pain after root canal
This trial tests if adding alprazolam (a mild anti-anxiety medicine) to standard painkillers can better manage pain after a root canal. It aims to find a more effective way to control post-procedure discomfort.
Rawalpindi, Punjab ProvinceAges 18–60 - NCT05315596Enrolling by invitation
Tracking pain and recovery answers after surgery
This study checks how patients report pain and recovery over time after surgery. It may help improve how hospitals understand and manage pain after operations.
JenaAges 18 years+ - NCT06386224Recruiting
Online pain self-management for pancreatitis pain
This study tests an online pain-management program for adults with chronic or recurrent acute pancreatitis. The program is done on your own device (or a loaner iPad) and is designed to help you learn skills to cope with pain and improve daily life.
Seattle, WashingtonAges 18 years+ - NCT06925152RecruitingPhase 4
Nerve block for C-section pain in complex surgery history
This study tests a targeted numbing injection (a nerve block) in the belly wall during C-sections to improve pain control and recovery for people who have had multiple or complex abdominal surgeries. It aims to see if this approach reduces the need for strong pain medicines.
Memphis, TennesseeAges 18–50 - NCT06696430Recruiting
Nudging to use TENS for pain after surgery
This trial tests whether a simple reminder (nudging) can encourage staff and patients to use a device called TENS, which uses mild electrical pulses to help reduce pain after urological surgery.
Gothenburg, VGRAges 18 years+ - NCT06977009Recruiting
Does tooth grinding relief help with post-dental pain?
This study tests whether reducing a tooth's contact with its opposite tooth before root canal treatment can lower pain after the procedure. It's for people with a dead nerve in a back molar that needs a crown.
Amman, Amman GovernorateAges 18–70 - NCT06569836Recruiting
Study on digital program for chronic knee pain
This trial tests a digital program to help people manage chronic knee pain. If you are 55 or older and have had knee pain recently, this study may be a good fit.
Hong KongAges 55 years+ - NCT04685486Recruiting
Virtual reality program to help burn pain
This trial tests whether virtual reality (immersive computer experiences) can help manage pain in people with burn injuries. It’s for burn patients who can safely participate without heavy sedation or certain mental health or substance-use issues.
New York, New YorkAges 8 years+ - NCT06595329RecruitingPhase 1
Pain relief after kidney cancer surgery: epidural vs spinal opioids
This trial compares two ways to manage pain after open kidney cancer surgery: an epidural (a thin tube placed near your spine) versus a single spinal injection of opioids. Both aim to control pain, but the study wants to see which method works better, with fewer side effects.
SplitAges 18 years+ - NCT07185425Recruiting
NeuroCuple patch for pain after C-section
This study tests a special sticky patch (NeuroCuple device) placed near your C-section incision to see if it helps with pain after delivery. It may offer a drug-free way to manage discomfort.
Falls Church, VirginiaAges 18 years+ - NCT07396753Recruiting
Nerve block to reduce opioid use after kidney donor surgery
This study tests a nerve block called Transversalis Fascia Plane Block to see if it lowers the amount of strong pain medicine (opioids) needed after a kidney donor surgery. It may help you have less pain and fewer side effects.
Istanbul, ZeytinburnuAges 18–80 - NCT07401147Recruiting
TENS for pain relief during first labor
This trial tests a gentle electrical device (TENS) to help manage pain during labor. It's for women having their first baby, with a healthy, single pregnancy, and no major health issues.
Tegucigalpa, Francisco Morazán DepartmentAges 18–45 - NCT07547618Recruiting
Pain Management in Recovery Room After Surgery
This study observes how much pain medication patients need right after surgery while they're in the recovery room. Researchers want to understand pain patterns to help improve comfort for future surgical patients.
Ankara, YenimahalleAges 18 years+ - NCT07653906Recruiting
Nerve block for upper abdominal cancer pain
This trial compares two nerve-block procedures to see which better relieves severe pain from cancers in the upper belly (like pancreas, stomach, liver, or bile duct). It may help if you have moderate to severe pain and are not pregnant or have certain medical conditions.
DhakaAges 18 years+ - NCT06962709Enrolling by invitation
Warmed lidocaine for less pain during eye injections
This trial tests whether warming the numbing medicine (lidocaine) before an eye injection reduces pain. If you're already getting an eye injection for any reason, you may be able to join.
Columbia, MissouriAges Any age - NCT06917651RecruitingPhase 3
Study of a new pain medicine for arm or leg injuries in the ER
This trial tests a fast-acting pain pill (sufentanil) placed under the tongue for people with moderate to severe pain from a single arm or leg injury. It aims to see if it works well in the emergency room.
FranceAges 18 years+ - NCT06344169RecruitingPhase 2/Phase 3
Pain relief after C-section with Naldebain
This trial tests a long-acting painkiller, Naldebain, for women having a planned C-section. It aims to see if it provides better pain control after the surgery.
Dalin, Chai-YiAges 20 years+ - NCT06515925Recruiting
Virtual group program for managing chronic pain
This study tests a virtual group program that combines medical care with integrative approaches like mindfulness and gentle movement to help adults manage chronic musculoskeletal pain.
Malden, MassachusettsAges 18 years+ - NCT05009771Recruiting
Testing a pain-control method after C-section
This study looks at how to better manage pain after a C-section using spinal anesthesia and either a patient-controlled IV pain pump or a specific pain medicine (naldebaein). You may be able to join if you’re scheduled for a C-section at 37–40 weeks and can take the usual pain medicines.
New Taipei City, TaiwanAges 20–40 - NCT06785350Recruiting
Smallest effective steroid dose for spine surgery pain
This study tests whether a very small amount of a steroid (betamethasone) placed around the surgical cut can help control pain after spine surgery. It aims to find the lowest dose that still works well, so patients may need fewer painkillers and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–65 - NCT07197710Recruiting
Imagined acupuncture for pain after spine surgery
This trial tests if imagining acupuncture, guided by a video, can help reduce pain after spinal surgery. It is for adults having their first spine surgery on one or two bones.
Boston, MassachusettsAges 18 years+ - NCT07054450Enrolling by invitation
Assessment and rehabilitation for chronic pinched nerve in the neck
This trial tests a program of assessment and rehabilitation (including physical exercise and possibly a nutraceutical supplement) for people with chronic cervical radiculopathy — a pinched nerve in the neck causing pain, numbness, or weakness in the arm. It may help reduce pain and improve function without surgery.
CraiovaAges 50–79 - NCT06940986Recruiting
Holistic pain self-management for military health system patients
This trial tests a holistic pain self-management program for people with long-term muscle or bone pain. It aims to help you take control of your pain through education and support, without relying only on medications.
Fairbanks, AlaskaAges 18 years+
Hear when a new Pain Management trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain management?
- Yes. Clin2 currently lists 349 recruiting pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.