Clinical trials · Los Angeles, CA
Pain clinical trials in Los Angeles
We’re tracking 85 recruiting pain studies with a site in or near Los Angeles — including Early Phase 1, Phase 1, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Los Angeles
- NCT05351801RecruitingPhase 2
Test cannabis-based treatment for nerve pain
This Phase 2 study tests cannabis-derived products to see if they reduce neuropathic (nerve-related) pain in veterans. It may help people whose pain is persistent and causes significant daily impact, especially if certain exam tests show allodynia (pain from normally non-painful touch).
West Los Angeles, CaliforniaAges 21 years+ - NCT06004804Recruiting
Psychological treatments for chronic pain in veterans
This study compares two group psychological treatments for chronic pain delivered over video conference. It aims to see if these treatments help reduce pain and improve quality of life for veterans.
West Los Angeles, CaliforniaAges 60–95 - NCT07276542RecruitingPhase 2/Phase 3
Ketamine for phantom limb pain: a six-month outpatient study
This study tests whether ketamine, given as an outpatient treatment, can reduce phantom limb pain over six months. You would come to a clinic for multiple ketamine sessions, with at least a week between each session, and be followed for a year.
Santa Monica, CaliforniaAges 18–65 - NCT05247255Enrolling by invitationEarly Phase 1
Nerve block during hip replacement surgery
This early-stage study tests whether a specific nerve block to numb the lower back area can make total hip replacement surgery more comfortable. It looks at patients who are having planned (elective) hip replacement and whether the nerve block is safe and works well.
Santa Monica, CaliforniaAges 18 years+ - NCT06778447Recruiting
Trial of disc tissue injection for degenerative disc disease
This study tests an experimental treatment that injects donated disc tissue (called an allograft) into damaged discs in your lower back. It's designed for people with chronic low back pain from disc degeneration who haven't found relief from non-surgical treatments.
Santa Monica, CaliforniaAges 22–85 - NCT07369024RecruitingPhase 2
Study of low-dose ketamine for sickle cell pain crisis
This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.
Torrance, CaliforniaAges 5–20 - NCT06985784Recruiting
Virtual reality for head and neck cancer patients and caregivers
This study tests whether using virtual reality can help reduce depression, anxiety, and pain in people with head and neck cancer and their caregivers. You and your caregiver may be able to use VR headsets together as part of your treatment.
Duarte, CaliforniaAges 18 years+ - NCT05612750Recruiting
Online therapy for chronic pain: CBT vs one-session relief
This study compares two online treatments for chronic pain: an 8-session cognitive behavioral therapy (CBT) program versus a single “empowered relief” session. It aims to see which approach helps people manage pain better over time.
Long Beach, CaliforniaAges 18 years+ - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Long Beach, CaliforniaAges 18 years+ - NCT07464639Enrolling by invitation
Comparing two ways to help shoulder pain with movement feedback
This study compares using ultrasound images (dynamic visual feedback) versus manual guidance to help activate shoulder blade muscles and improve space in the shoulder joint for people with shoulder pain when lifting their arm.
Long Beach, CaliforniaAges 18–70 - NCT07209566Recruiting
Muscles, nerves, and period pain in women
This study looks at how your muscles and nervous system relate to period pain. It compares women with and without painful periods to understand why some have more pain.
Azusa, CaliforniaAges 18–35 - NCT07335913RecruitingPhase 1
Testing SBS-147 in healthy adults for safety
This study tests a new drug, SBS-147, in healthy adults to see if it's safe and how the body processes it. It may help find the right dose for future studies in people with certain conditions.
Cypress, CaliforniaAges 18–55 - NCT03877653Recruiting
Freedom-1 treatment for long-term knee pain in adults
This study tests a procedure called Freedom-1 to reduce long-term, limiting knee pain from knee arthritis. It may help if other non-surgical options didn’t work and you meet specific knee and health requirements.
Placentia, CaliforniaAges 18 years+ - NCT03876054Recruiting
Tracking outcomes after Abbott neurostimulator implantation
This study follows people long-term after they get an Abbott device implanted to help with chronic pain. It aims to learn how well the therapy works in real-world care over time.
Pomona, CaliforniaAges 18 years+ - NCT07145346Enrolling by invitationPhase 4
Suzetrigine for pain relief after multiple rib fractures
This trial tests a new medicine, suzetrigine, for managing acute pain in adults who have broken three or more ribs from a blunt injury. It aims to see if this painkiller works well and is safe for you.
Orange, CaliforniaAges 18 years+ - NCT07826936RecruitingEarly Phase 1
Nerve block for severe abdominal pain in the emergency department
This trial tests whether a nerve block can provide better pain relief for severe abdominal pain that hasn't improved with standard pain medicine. It's for people who are not candidates for surgery and are in the emergency department or already in the hospital.
Orange, CaliforniaAges 18 years+ - NCT07581080Recruiting
Biofield therapy to ease fatigue from cancer immunotherapy
This study tests whether Reiki—a hands-on healing practice—can help reduce severe tiredness in cancer patients receiving immunotherapy drugs. If it works, it could offer patients another way to manage fatigue alongside their cancer treatment.
Orange, CaliforniaAges 18 years+ - NCT06020677Recruiting
Study on Latinx children's pain after surgery
This study looks at how parents manage their child's pain after surgery, focusing on Latinx families who speak Spanish at home. By understanding these experiences, doctors hope to improve pain care for children.
Orange, CaliforniaAges 2–12 - NCT01719055Recruiting
Long-term follow-up for Boston Scientific pain nerve stimulation
This study looks at how well a Boston Scientific nerve stimulation device works over the long term for pain in everyday care. You may be able to join if you’re already being set up to use one of these approved systems and can reliably report your pain outcomes.
Fountain Valley, CaliforniaAges 18 years+ - NCT01550575Recruiting
Study of outcomes in people treated with Boston Scientific devices
This study looks back at what happened to patients after treatment (or if they could have used) Boston Scientific medical devices. It may help improve how these devices are used and understand real-world results.
Fountain Valley, CaliforniaAges 18 years+ - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Fountain Valley, CaliforniaAges 18 years+ - NCT06394830RecruitingPhase 2
Testing VNX001 for bladder pain syndrome
This study tests a new treatment (VNX001) for people with interstitial cystitis or bladder pain syndrome (IC/BPS). You must have already taken part in an earlier study of this drug to join. The goal is to see if it safely reduces bladder pain.
Tustin, CaliforniaAges 18 years+ - NCT07061769Enrolling by invitation
Using a gentle head device to help with nerve pain from chemo
This trial tests a low-intensity cranial PEMF device to see if it can reduce nerve pain caused by chemotherapy. Participants use the device at home and receive text messages to track their symptoms.
Newport Beach, CaliforniaAges 18–60 - NCT04984291Recruiting
Study of shoulder replacement implants for eligible adults
This trial looks at a specific shoulder replacement implant and follow-up care for people who need a shoulder arthroplasty (shoulder replacement) for certain joint problems or fractures. You may be a candidate if you can take part in required visits and your shoulder muscles and bone are suitable.
Irvine, CaliforniaAges 20 years+
Hear when a new Pain trial opens near Los Angeles, CA
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Pain trials in other cities
Where these studies are running near Los Angeles
Institutions with a site for the recruiting pain studies listed above.
- Pain Medicine Associates, Inc. · 2 studies
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA · 2 studies
- AltaSciences, Inc
- Ark Clinical Research
- Azusa Pacific University
- Children's Hospital of Orange County
- City of Hope
- Conejo Pain Specialists
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pain studies in California.
Common questions
- Are there pain clinical trials near Los Angeles?
- Yes. We're currently tracking 85 recruiting pain studies with a site near Los Angeles, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study near Los Angeles?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Los Angeles to take part?
- Not necessarily. These studies have a site near Los Angeles, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open near Los Angeles regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.