Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 750 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Sun City, ArizonaAges 40–80 - NCT07204652Recruiting
Colonoscopy test for Parkinson's disease detection
This study tests whether a protein in colon tissue can help diagnose Parkinson's disease. People with Parkinson's who already need a routine colonoscopy may participate.
Portland, OregonAges 40–99 - NCT07786116Recruiting
Gut bacteria in Parkinson's disease and related conditions
This study looks at how certain gut bacteria (methanogens) are involved in the progression of Parkinson's disease and related conditions. It aims to understand the connection between gut health and brain health, which may lead to better treatments.
Cambridge, CB2Ages 55 years+ - NCT06705517Recruiting
Mediterranean diet study for Parkinson's disease
This trial tests whether a Mediterranean diet can help people with Parkinson's disease. You would either follow your usual diet or switch to a Mediterranean diet for six months and provide blood and stool samples.
Varese, VareseAges 40–85 - NCT07217054Recruiting
Parkinson's and RBD diagnosis via colon biopsy
This trial uses a small piece of colon tissue, taken during a routine colonoscopy, to look for a protein linked to Parkinson's disease and REM sleep behavior disorder (RBD). It aims to improve diagnosis for these conditions.
Branford, ConnecticutAges 40–99 - NCT04994015RecruitingTeam says not enrolling
Genetic registry for people with Parkinson’s
This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.
Birmingham, AlabamaAges 18 years+ - NCT07630545RecruitingPhase 1
Testing a new drug for Parkinson's disease
This study tests an experimental drug, MTX325, in people with Parkinson's disease. The goal is to see if it is safe and how the body processes it, which may lead to new treatment options.
AdelaideAges 18–75 - NCT07568067Recruiting
Accelerated Brain Stimulation for Parkinson's Disease
This trial tests a new type of brain stimulation (called temporal interference stimulation) targeted at specific brain regions to help improve Parkinson's disease symptoms. Researchers will use MRI imaging and behavioral assessments to see if this approach can reduce movement problems and improve quality of life.
Guangzhou, GuangdongAges Up to 85 years - NCT04997642Recruiting
Parkinson’s patient database for memory and movement tracking
This study builds a research database of people who receive care for Parkinson’s disease, including those with mild memory problems or dementia. It aims to collect consistent information that researchers can use to better understand Parkinson’s and related thinking changes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05997043RecruitingEarly Phase 1
Botulinum toxin for overactive bladder in Parkinson's disease
This trial tests if botulinum toxin A injections can help control overactive bladder symptoms in people with Parkinson's disease who haven't gotten enough relief from standard bladder medications. It aims to see if the treatment is safe and effective.
Guangzhou, GuangdongAges 25–80 - NCT06174948Recruiting
CUE1 device for Parkinson's and related movement disorders
This trial tests a small device called CUE1 that gives gentle vibrations on the chest to help improve movement and balance in people with Parkinson's disease and similar conditions. It may help if you have trouble with walking or stability.
LondonAges 18 years+ - NCT07685873Recruiting
MAO-B PET imaging in Parkinson's and related diseases
This study uses a special type of brain scan (PET/CT) to look at a protein called MAO-B in people with Parkinson's disease or related conditions. The scan may help doctors understand more about the disease and could be part of your regular care.
Hefei, AnhuiAges 18–90 - NCT07761936RecruitingPhase 3
Safinamide for Parkinson's disease pain
This study tests whether safinamide, an add-on medication for Parkinson's disease, can reduce chronic pain in people who also experience motor fluctuations (times when symptoms return between doses). It aims to see if this treatment can improve pain and quality of life.
Verona, VenetoAges 18 years+ - NCT07752355Recruiting
Parkinson's subtypes and causes in young onset disease
This study looks at different types of Parkinson's disease, especially in people diagnosed before age 50. It involves a small skin biopsy to help understand what causes the disease.
New York, New YorkAges 18 years+ - NCT07265596RecruitingPhase 2
Brain Scan Study for Early Parkinson's Disease
This trial uses a special brain scan (PET scan) to look at early changes in people who have early signs of Parkinson's disease. The goal is to learn more about how Parkinson's develops over time.
New Haven, ConnecticutAges 18 years+ - NCT07567794Recruiting
Gut-Brain Connection Study in Parkinson's Disease
This research examines how the gut and brain are connected in Parkinson's disease and aims to better understand the disease. You'd participate in visits and tests over three years, including some involving your digestive system.
Stanford, CaliforniaAges 21–80 - NCT07411664Enrolling by invitation
Balance and walking study for stroke, Parkinson's, or multiple sclerosis
This study uses special motion-tracking tools to measure balance and trunk control in people with first-time stroke, Parkinson’s, or multiple sclerosis. It aims to understand how these conditions affect stability, which could help tailor rehabilitation.
Kaposvár, Somogy CountyAges 18–80 - NCT07330258Recruiting
Observing Parkinson's over time in people still having movement symptoms
This study follows people with Parkinson's disease who still have movement symptoms despite taking medication. It aims to understand how the disease changes over time, which could help improve future treatments.
Phoenix, ArizonaAges 45–75 - NCT04101968Recruiting
Study of GBA changes in Parkinson’s using multiple tests
This study looks at people with Parkinson’s who carry a specific genetic change in the GBA gene. It uses several tests (including brain scans) to understand the disease better and may help guide future treatments.
Portland, OregonAges 18–80 - NCT04735458Recruiting
Brain network study for Parkinson’s or essential tremor
This study looks at how “inhibitory control” brain networks work in people with Parkinson’s disease or essential tremor. If you are eligible for surgery and can do the study tasks, your results may help researchers better understand movement disorders and guide future treatments.
Birmingham, AlabamaAges 18 years+ - NCT04848077Recruiting
Smartphone exercise program for early Parkinson’s patients
This trial tests whether a motivating phone-based exercise plan can help people with early-stage Parkinson’s move more safely and consistently. You may qualify if you can walk on your own, understand Dutch, and are fairly inactive right now.
Nijmegen, GelderlandAges 18 years+ - NCT05065060Recruiting
Parkinson study tracking health online and long-term
This study aims to better understand Parkinson’s disease over time by collecting health information online. You may join if you have Parkinson’s, or if you don’t, to compare changes and help researchers find useful markers.
San Francisco, CaliforniaAges 18 years+ - NCT05066763Recruiting
Surveys for people with Parkinson’s and their care partners
This trial is for people with Parkinson’s disease, their care partners, and health professionals who work with people with Parkinson’s. The Parkinson’s Foundation will contact you to collect survey information and may invite you to future research opportunities.
Miami, FloridaAges 18 years+ - NCT05516719Recruiting
Study tracking I2BS in Parkinson’s over time
This study follows people with Parkinson’s to see how “I2BS” changes over time using special brain scans and other tests. It may help researchers better understand Parkinson’s and improve how it’s measured in future trials.
Exeter, DevonAges 25 years+
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 750 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.