Clinical trials · Philadelphia, PA
Parkinson’s disease clinical trials in Philadelphia
We’re tracking 17 recruiting parkinson’s disease studies with a site in or near Philadelphia — including Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT04994015RecruitingTeam says not enrolling
Genetic registry for people with Parkinson’s
This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Philadelphia, PennsylvaniaAges 50–85 - NCT06285643RecruitingPhase 2
Gene therapy for moderate Parkinson's disease
This trial tests a gene therapy (AAV2-GDNF) to see if it can slow or improve symptoms of Parkinson's disease. It is for people who have had moderate Parkinson's for 4 to 10 years and still respond to levodopa therapy.
Philadelphia, PennsylvaniaAges 45–75 - NCT04071847Recruiting
Study tracking results after Abbott deep brain stimulator surgery
This study follows people who are getting a new Abbott deep brain stimulator (DBS) device or replacing the battery/implantable pulse generator to see how outcomes change over time. It mainly applies to certain DBS targets and diagnoses, and it uses follow-up visits to track results.
Philadelphia, PennsylvaniaAges Any age - NCT04997642Recruiting
Parkinson’s patient database for memory and movement tracking
This study builds a research database of people who receive care for Parkinson’s disease, including those with mild memory problems or dementia. It aims to collect consistent information that researchers can use to better understand Parkinson’s and related thinking changes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Philadelphia, PennsylvaniaAges 18–80 - NCT07330258Recruiting
Observing Parkinson's over time in people still having movement symptoms
This study follows people with Parkinson's disease who still have movement symptoms despite taking medication. It aims to understand how the disease changes over time, which could help improve future treatments.
Philadelphia, PennsylvaniaAges 45–75 - NCT07265596RecruitingPhase 2
Brain Scan Study for Early Parkinson's Disease
This trial uses a special brain scan (PET scan) to look at early changes in people who have early signs of Parkinson's disease. The goal is to learn more about how Parkinson's develops over time.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04373317RecruitingPhase 4
Comparing two medicines for hallucinations in Parkinson's disease
This study compares two drugs, pimavanserin and quetiapine, to see which works better for hallucinations or delusions caused by Parkinson's disease. The goal is to help patients manage these symptoms more effectively.
Philadelphia, PennsylvaniaAges 40 years+ - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Philadelphia, PennsylvaniaAges 40–80 - NCT06377033Recruiting
Using health records to advance genomic medicine for all
This study uses electronic health records to learn how to improve genomic medicine across a diverse health system. It may help make DNA-based healthcare more accessible and effective for people with certain conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04477785Recruiting
Study to track Parkinson’s signs using imaging, spinal fluid, and genes
This study is building a large, detailed group of people—some with Parkinson’s and some at higher risk—to understand early changes over time. It uses brain imaging (DaTscan SPECT), sometimes spinal fluid tests (lumbar puncture), and genetic information to help researchers better measure disease and develop future treatments.
Philadelphia, PennsylvaniaAges 30 years+ - NCT05539196Recruiting
Registry for Exablate treatment in Parkinson’s with medication problems
This trial is a real-world registry that follows people with Parkinson’s who are planning to get an Exablate 4000 procedure (a focused ultrasound treatment) for one-sided symptoms that are difficult to control with medication. It mainly checks outcomes and safety over time, helping doctors understand how well this treatment works in everyday care.
Philadelphia, PennsylvaniaAges 30–99 - NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Willow Grove, PennsylvaniaAges 40–85 - NCT06916260Recruiting
Light therapy study for people with Parkinson's disease
This study tests whether light therapy can help people with Parkinson's disease. Participants will receive light therapy sessions and have their symptoms checked before, after, and three months later.
Newark, DelawareAges 50–80 - NCT04496973Recruiting
Parkinson’s disease research registry for adults
This registry asks people with Parkinson’s disease to join a research program at the University of Delaware. Being in the registry may help you get invited to investigator-led studies that could improve understanding or treatment of Parkinson’s.
Newark, DelawareAges 21–100 - NCT04616508Recruiting
Online arm movement training for people with Parkinson’s
This study uses online tasks to look at how people with Parkinson’s control reaching movements. You may benefit by contributing to research that could improve understanding and future treatments for movement problems.
Newark, DelawareAges 18–85
Hear when a new Parkinson’s disease trial opens near Philadelphia, PA
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Parkinson’s disease trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting parkinson’s disease studies listed above.
- University of Pennsylvania · 9 studies
- Thomas Jefferson University Hospital · 4 studies
- University of Delaware · 3 studies
- Abington Neurology
- Center for Interventional Pain & Spine
- Corporal Michael J. Crescenz VA Medical Center
- Philadelphia MultiService Center, Philadelphia, PA
What taking part in a parkinson’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting parkinson’s disease studies in Pennsylvania.
Common questions
- Are there parkinson’s disease clinical trials near Philadelphia?
- Yes. We're currently tracking 17 recruiting parkinson’s disease studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a parkinson’s disease study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New parkinson’s disease studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.