Clinical trials
Patent Ductus Arteriosus clinical trials
Below are recruiting patent ductus arteriosus clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05011149RecruitingPhase 3
Medicine for early treatment of a leaking heart vessel
This trial studies whether giving medicine soon can help preterm babies with a patent ductus arteriosus (a temporary leaking blood vessel in the heart). It aims to see if early treatment improves outcomes for very early gestational age infants.
Orange, CaliforniaAges Up to 3 days - NCT07338370Recruiting
PGE2 levels and heart duct closure in preterm babies
This trial measures a substance called prostaglandin E2 (PGE2) in preterm babies to see if it can predict whether a heart blood vessel (ductus arteriosus) will close on its own or need treatment. This could help doctors decide when to use medication to close the vessel.
Cairo, AbbasiaAges 1 day–1 week - NCT05264753Recruiting
Follow-up study for a device that closes an abnormal heart blood vessel
This study checks how well and how safely the Occlutech PDA Occluder works over time to close a patent ductus arteriosus (PDA). You may be considered if your PDA can be treated with this non-surgical device and you can return for follow-up visits.
MontrealAges Any age - NCT05547165Recruiting
Closing a leaky heart connection early in very small babies
This trial compares an early procedure to close a heart vessel called the ductus arteriosus versus careful observation alone in very low-birth-weight preterm infants. It aims to see whether closing the vessel early can improve outcomes and be done safely.
Birmingham, AlabamaAges 1 week–1 month - NCT06627374Recruiting
Ultrasound to check duct closure in premature babies
This study uses ultrasound to see if a heart blood vessel called the ductus arteriosus has closed after treatment in premature infants. It aims to find a better way to monitor the response to treatment without X-rays.
Roma, romaAges Up to 4 weeks - NCT05340582RecruitingPhase 2
Ibuprofen plus acetaminophen for a heart condition in very premature babies
This Phase 2 study tests whether giving ibuprofen together with acetaminophen improves outcomes for an important heart connection (PDA) in extremely premature infants. It compares how this medicine approach affects the baby’s heart-related measurements and short-term progress.
Newcastle, New South WalesAges Up to 6 months - NCT06646250Recruiting
New ultrasound for steady brain monitoring in newborns
This trial uses a new ultrasound device (NeoDoppler) to watch blood flow in a baby's brain continuously. It aims to see if this gentle, bedside tool can help doctors monitor babies—especially those born early or with certain health concerns—without moving them.
TrondheimAges birth–1 year - NCT06658496Recruiting
Studying kidney health in very premature newborns
This trial looks at how well kidneys work in very premature babies (born before 32 weeks). It uses special sensors to monitor kidney health in the first few days of life.
Madison, WisconsinAges 1 minute–1 week - NCT07143201RecruitingPhase 2
Precision dosing of ibuprofen for PDA in premature babies
This study tests a personalized way to give ibuprofen to very premature babies with a heart condition called PDA. It aims to see if adjusting the dose can help close the heart opening more safely.
Hamilton, OntarioAges Up to 6 months - NCT07646704Recruiting
Study of HeartR PDA Heart Device Safety and Function
This study follows patients who had a small heart device (HeartR PDA Occluder) placed to close an opening in their heart called a PDA. Researchers will check how well the device is working and track the patient's health over time.
Pekanbaru, RiauAges 6 months+ - NCT07114718Recruiting
Stent for babies with heart defect needing extra blood flow
This trial tests a special stent for babies with a heart defect that needs a temporary blood vessel to stay open. The stent is placed to help blood flow to the lungs until the baby can have a more permanent surgery.
Los Angeles, CaliforniaAges 1 minute–6 months
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Common questions
- Are there clinical trials for patent ductus arteriosus?
- Yes. Clin2 currently lists 11 recruiting patent ductus arteriosus studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a patent ductus arteriosus trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a patent ductus arteriosus trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.