Precision dosing of ibuprofen for PDA in premature babies
Part of Genetic & congenital, Heart & circulation, Women’s health & pregnancy clinical trials.
This study tests a personalized way to give ibuprofen to very premature babies with a heart condition called PDA. It aims to see if adjusting the dose can help close the heart opening more safely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby is born at or before 27 weeks and 6 days of pregnancy.
- Your baby is a patient in the NICU at McMaster Children's Hospital.
- Your baby has a PDA (a heart condition) that needs treatment, based on a heart ultrasound.
- You give permission for your baby to be in the study.
- Your baby does not have major birth defects, serious infections, or problems with the liver or kidneys.
- Your baby does not have any reason they cannot take ibuprofen (like severe jaundice, feeding issues, bowel problems, bleeding, or very low platelet count).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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