Clinical trials
Patients Above 18 Years clinical trials
Below are recruiting patients above 18 years clinical trials, each written for real people, not researchers. We’re tracking 70 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06561620RecruitingPhase 4
Befotertinib after surgery for early-stage lung cancer
This trial tests a pill called befortinib for people with early-stage lung cancer who have had surgery. It aims to lower the chance of the cancer coming back. You might qualify if your tumor had certain high-risk features and you still have cancer DNA in your blood after surgery.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05928767Recruiting
Using frailty scores to predict death in ICU sepsis
This trial checks whether a “frailty” rating (how physically/mentally vulnerable someone is) can predict the risk of death in ICU patients with sepsis shock. It may help doctors identify higher-risk patients earlier and tailor care.
BéthuneAges 18–65 - NCT06560801RecruitingPhase 4
Dapagliflozin for kidney health after transplant
This trial tests whether taking dapagliflozin (a drug often used for diabetes and heart health) can help improve kidney structure and blood flow in people who received a kidney transplant at least 9 months ago. It may benefit those whose kidney function is stable, regardless of whether they have diabetes.
Erlangen, BavariaAges 18–75 - NCT07109323RecruitingPhase 1/Phase 2
Stem cell transplant plus CAR-T for aggressive myeloma
This trial tests combining a stem cell transplant with a special immune cell therapy (BCMA CAR-T) to treat very aggressive multiple myeloma. The goal is to see if this powerful one-two punch can help people whose myeloma is hard to control.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT07263529Recruiting
Iron pills for women with low iron but not anemic
This trial tests whether oral iron therapy can prevent anemia in women who have low iron stores but normal blood counts. It aims to find out if taking iron helps improve energy and overall health.
Kâğıthane, IstanbulAges 18–55 - NCT07280416Recruiting
Sleep changes in first year after cancer diagnosis
This study follows people who are newly diagnosed with cancer to see how their sleep changes during the first year. It looks at whether treatments like chemo or immunotherapy affect insomnia.
Le Puy-en-VelayAges 18–80 - NCT07557277Recruiting
Gum Recession and Quality of Life Study
This study looks at how gum recession (when gums pull back from teeth) affects your quality of life and oral health. Researchers will ask you questions and examine your teeth to understand this connection better.
Rohtak, HaryanaAges 18–45 - NCT05108948Recruiting
Study factors linked to better quality of life after spine surgery
This study looks at what helps adults with spinal deformity have a better quality of life one year after surgery. It may help doctors understand which patients benefit most and how to improve follow-up care.
BrugesAges 18 years+ - NCT07285005RecruitingPhase 3
Study of an oral drug for venous, lymphatic, and certain overgrowth syndromes
This trial tests whether the study drug KP-001 can help reduce symptoms like pain, fatigue, or bleeding caused by certain vascular malformations (abnormal blood vessel growths) that can't be surgically removed or haven't responded to other treatments. It's for people age 2 and older with specific conditions such as common venous malformations, lymphatic malformations, or KTS/CLOVES syndrome.
Charleston, South CarolinaAges 2 years+ - NCT05372640RecruitingPhase 1
Drug combo trial for rare cancers with shared NUT features
This Phase 1 trial tests the safety and early signs of effectiveness of combining two anti-cancer drugs (ZEN003694 and abemaciclib) in teens and adults with metastatic or unresectable NUT carcinoma, breast cancer, and other solid tumors. It may help by finding a safer dose and whether the drug combination can shrink or control tumors that do not respond to standard treatments.
Los Angeles, CaliforniaAges 12 years+ - NCT06229288RecruitingPhase 3
Pneumonia treatment: amoxicillin alone vs. with clavulanate for adults 65+
This trial compares two antibiotics for older adults hospitalized with pneumonia. It aims to see if amoxicillin alone works as well as amoxicillin combined with clavulanate, which might reduce side effects.
Saint-Nazaire, FranceAges 65 years+ - NCT06860919Recruiting
Transition care for young adults with esophageal atresia
This trial studies a special follow-up program for young adults born with a connection problem in their esophagus (the tube that carries food). The goal is to see if a transitional consultation helps manage long-term health needs.
ParisAges 18–30 - NCT06891417RecruitingPhase 1/Phase 2
Chlamydia mRNA vaccine study for adults 18-29
This study tests a new mRNA vaccine designed to prevent chlamydia infection. It is for adults aged 18 to 29 who have a higher risk of getting chlamydia.
Bruce, Australian Capital TerritoryAges 18–29 - NCT07049159RecruitingPhase 2
Testing a new oral vaccine to prevent shigella and ETEC infection
This trial tests an oral vaccine designed to protect against two common causes of severe diarrhea: shigella and ETEC bacteria. Healthy adults aged 18 to 50 will receive the vaccine and later be exposed to the bacteria to see if it works.
Baltimore, MarylandAges 18–50 - NCT07516418RecruitingPhase 1
RSV and Flu H5 Vaccine Formulations Study
This study tests different versions of experimental vaccines designed to protect against RSV (a common respiratory virus) and flu H5. You'll receive one of these vaccines and be monitored to see how safe it is and how your body responds.
Griffith, QueenslandAges 18–49 - NCT05009927RecruitingPhase 2
Check whether continuing imatinib works after long GIST control
This trial studies people with advanced or metastatic gastrointestinal stromal tumor (GIST) who have been on the drug imatinib for 10 years with stable, non-growing disease. The goal is to see how effective it is to keep imatinib going after this long period.
BesançonAges 18 years+ - NCT05709288RecruitingPhase 1
Gene therapy for teens with hemophilia B
This Phase 1 study tests a one-time gene therapy treatment (BBM-H901) for boys ages 12 to 18 with hemophilia B. It aims to see if the treatment is safe and can help the body make more clotting factor over time.
Tianjin, Tianjin MunicipalityAges 12–18 - NCT05927701Recruiting
Long-term outcomes in adolescent scoliosis patients
This study asks people with adolescent idiopathic scoliosis about how they feel today and how they use healthcare services. It compares people who had surgery versus those who were treated without surgery, but only includes those with long follow-up since their teen years.
BrugesAges 18 years+ - NCT07590635Recruiting
Heart Recovery Program Using Online Health Tools
This study tests a new heart rehabilitation program that combines online tools with personalized support for people who've had heart procedures. It aims to help you recover safely and manage your heart health from home.
BergenAges 18 years+ - NCT06848166RecruitingEarly Phase 1
Middle meningeal artery embolization for resistant chronic migraine
This study tests a procedure called 'middle meningeal artery embolization' using a special glue-like material (SQUID) to treat chronic migraine that hasn't responded to other treatments. The goal is to see if blocking blood flow to the membrane around the brain can reduce migraine attacks.
Bishkek, BishkekAges 35–59 - NCT06622603RecruitingPhase 4
Testing lower doses of febuxostat in well-controlled gout
This trial tests if gradually lowering the dose of the gout medication febuxostat is safe for people whose gout has been well-controlled for at least 5 years. The goal is to see if a lower dose can still keep uric acid levels in a healthy range.
Seongnam-si, Gyeonggi-doAges 19–79 - NCT06944262Recruiting
Cancer-related stress study for patients and caregivers
This study looks at stress after a cancer diagnosis and asks patients and caregivers what kind of support they want. It may help improve care for people coping with cancer.
Lille, NordAges 18 years+ - NCT06994208Recruiting
Melanoma study for adults under 40
This study looks at the characteristics of melanoma in people younger than 40. It may help doctors understand how this cancer affects younger adults.
Genoa, LiguriaAges 18–39 - NCT07315932Recruiting
Hormone therapy views in teenagers
This trial is a survey asking girls aged 11 to 17 how they feel about starting hormone replacement therapy for hypogonadism. The goal is to understand their experiences and views.
StrasbourgAges 11–18
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Common questions
- Are there clinical trials for patients above 18 years?
- Yes. Clin2 currently lists 70 recruiting patients above 18 years studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a patients above 18 years trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a patients above 18 years trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.