Clinical trials
Traumatic Brain Injury (TBI) Patients clinical trials
Below are recruiting traumatic brain injury (tbi) patients clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07783828Recruiting
Chatbot-guided exercise for brain injury recovery
This trial tests whether a smartphone chatbot can help people recovering from a mild brain injury stick to a personalized, guided exercise program. It aims to improve their physical and mental well-being during recovery.
TaipeiAges 18 years+ - NCT07455136Recruiting
Blood test for traumatic brain injury diagnosis and monitoring
This study is testing a new blood-based test to help doctors diagnose traumatic brain injury (TBI) and track recovery or complications. If you have had a head injury and a CT scan as part of your care, you may be able to join.
Sacramento, CaliforniaAges 18 years+ - NCT06963775Enrolling by invitation
Brain injury study using magnetic brain stimulation
This study uses a non-invasive magnetic stimulation technique to measure brain activity in people who have had a traumatic brain injury (TBI). It aims to see if this tool can help doctors better understand and track recovery after a head injury.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05236010Recruiting
Brain stimulation plus cognitive training for mild TBI memory and thinking
This trial studies whether brain stimulation through the scalp can improve cognitive (thinking and memory) training in people with chronic mild traumatic brain injury (TBI). Participants train on thinking tasks while receiving a targeted “control network neuromodulation” approach to see if it enhances training results.
Minneapolis, MinnesotaAges 18–59 - NCT07256704Recruiting
Hypnosis and attention for neurological conditions
This study looks at whether hypnosis can help improve attention in people with conditions like stroke, traumatic brain injury, or multiple sclerosis. It may help if you have trouble concentrating or focusing.
LucerneAges 18 years+ - NCT06293300RecruitingPhase 2
Botulinum toxin for light sensitivity after brain injury
This study tests if botulinum toxin type A (Botox) can reduce long-term light sensitivity in people who have had a traumatic brain injury at least a year ago. You must have had light sensitivity for 6 months or more and not have had Botox for face or mouth conditions before.
Miami, FloridaAges 18 years+ - NCT07483528Enrolling by invitation
Ways to help people with chronic brain injury manage health
This study compares different ways to help people with long-term traumatic brain injury (TBI) manage their health care. If you have had a TBI for at least a year and see a brain injury doctor, you may be able to join—especially if you also have other health conditions or use multiple medications.
Indianapolis, IndianaAges 18 years+ - NCT06583252Recruiting
Monitoring care for severe traumatic brain injury
This study tests a special monitoring approach for people with severe traumatic brain injury who are not opening their eyes or following commands. The goal is to see if close watching and coordinated care can improve recovery.
Changsha, HunanAges 18 years+ - NCT07733284RecruitingEarly Phase 1
Home walking program to boost thinking skills after TBI
This study tests whether a home-based walking program can improve thinking skills like memory and attention in people with traumatic brain injury (TBI). Eligible participants are 18 to 65, can walk briskly without help, and have noticed problems with thinking since their injury.
East Hanover, New JerseyAges 18–65 - NCT06595914Enrolling by invitation
Improving education for mild traumatic brain injury
This trial is working to improve how doctors and nurses teach patients about mild traumatic brain injury (mTBI) in the emergency room and after they go home. It may help you get clearer information and support during recovery.
Milwaukee, WisconsinAges 18 years+ - NCT06465290Recruiting
Brain recovery treatment for recent stroke with ankle stiffness
This trial tests a treatment to help your brain recover after a stroke. It focuses on improving ankle movement and leg strength using exercises that promote brain rewiring.
Baltimore, MarylandAges 30–85 - NCT03559114RecruitingPhase 3
Preventing blood clots after severe brain injury
This trial tests whether taking an anti–blood clot medicine (dalteparin) and using leg compression can reduce dangerous blood clots after a severe traumatic brain injury. It may help lower the chance of clots forming when people are immobile and at higher risk.
Calgary, AlbertaAges 18 years+ - NCT04124029Recruiting
Study how mild brain injuries may relate to dementia
This study looks at how past mild traumatic brain injury may contribute to brain changes seen in chronic traumatic encephalopathy (CTE) and Alzheimer’s disease (AD). It may help researchers understand risk and brain markers by comparing people with mild or moderate TBI, people with mild memory problems, and healthy controls.
Boston, MassachusettsAges 30–90 - NCT04400266RecruitingPhase 4
Buspirone and melatonin for depression after a brain injury
This trial studies whether the medicines buspirone and melatonin can reduce depression symptoms in people who had a mild or moderate traumatic brain injury (TBI) at least 3 months ago. It may help if you have ongoing depression after TBI and can safely take study medications and attend regular visits, including MRI scans.
Boston, MassachusettsAges 18–64 - NCT04995068Recruiting
Predicting Brain Lesion Risk After Mild Head Injury
This trial studies how to predict who may develop small brain injuries seen on CT scans after a mild traumatic brain injury. It may help doctors decide who needs closer monitoring or follow-up imaging.
StockholmAges 15 years+ - NCT05022940Recruiting
Track recovery and participation after adult brain injury rehab
This study follows adults with traumatic brain injury (TBI) during and after rehabilitation, to better understand how recovery and daily participation change over time. It may help improve rehab programs for people like you in the future.
Montreal, QuebecAges 17 years+ - NCT05084352Recruiting
Monitoring vital signs to predict recovery after head injury
This study checks vital signs (like heart rate and breathing) in the first hours after a traumatic brain injury to predict whether neurological function may decline. It may help doctors spot patients at higher risk sooner and adjust care earlier.
Baltimore, MarylandAges 18–79 - NCT05095857RecruitingPhase 4
Ketamine to improve care in severe acute brain injury
This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.
CopenhagenAges 18 years+ - NCT05205174Recruiting
Check a scalp sensor to detect brain swelling after injury
This study tests whether a sensor on the scalp can detect a wave of abnormal electrical activity in the brain after a traumatic brain injury (TBI). The goal is to help clinicians monitor and possibly treat dangerous pressure build-up in the brain.
Minneapolis, MinnesotaAges Any age - NCT05402761Recruiting
Nurse-guided sleep program for insomnia after brain injury
This trial studies whether nurse-guided behavioral sleep therapy can improve insomnia in people recovering after a traumatic brain injury (TBI). It may help you sleep better by targeting sleep habits and insomnia symptoms.
TaipeiAges 20–65 - NCT05533060Recruiting
Collecting brain injury data from people treated soon
This study collects medical and test information from people who have a confirmed brain injury (TBI) and arrive at the emergency room within 12 hours. Doctors hope the collected clinical and lab data will help better understand TBI and improve future care.
ShanghaiAges Any age - NCT05725993Recruiting
Study of tiny blood-vessel brain injury after head trauma
This study follows people with a moderate, non-penetrating traumatic brain injury (TBI) to see how small blood-vessel damage changes over time. It uses brain scans to learn what happens after a serious accident, which may help improve future care.
Philadelphia, PennsylvaniaAges 18–65 - NCT05782244RecruitingPhase 2
Sildenafil trial for long-term brain blood-flow problems after TBI
This Phase 2 study tests whether sildenafil (a medication better known for erectile function) can improve long-term symptoms and brain blood-flow issues after a past traumatic brain injury (TBI). It may help by improving blood vessel function in the brain and possibly reducing persistent post-concussion symptoms.
Philadelphia, PennsylvaniaAges 18–70 - NCT05855252Recruiting
Study on monitoring and outcomes after moderate to severe head injury
This observational study follows adults with moderate to severe traumatic brain injury to understand care and outcomes. It collects information from the first 48 hours in the ICU and may help improve how clinicians monitor and treat patients in the critical early period.
Kogarah, New South WalesAges 18 years+
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Traumatic Brain Injury (TBI) Patients trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for traumatic brain injury (tbi) patients?
- Yes. Clin2 currently lists 97 recruiting traumatic brain injury (tbi) patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a traumatic brain injury (tbi) patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a traumatic brain injury (tbi) patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.