Clinical trials
Pediatric Oncology clinical trials
Below are recruiting pediatric oncology clinical trials, each written for real people, not researchers. We’re tracking 66 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06199427RecruitingPhase 2
Preventing graft-versus-host disease after stem cell transplant for immune disorders
This trial tests a combination of two drugs, ruxolitinib and PTCy, to prevent graft-versus-host disease (a common complication) in children receiving a stem cell transplant for inborn errors of immunity. The goal is to make the transplant safer and more effective.
MoscowAges birth–21 years - NCT06071897RecruitingPhase 3
Chemo-immunotherapy for high-risk neuroblastoma
This trial tests a combination of chemotherapy and immunotherapy as a first treatment for children and young adults with high-risk neuroblastoma. The goal is to see if this approach can improve outcomes.
MoscowAges 1.5 years–18 years - NCT05518383RecruitingPhase 4
Pediatric B-cell lymphoma treatment study using established care
This trial studies treatment for children and teens with certain B-cell non-Hodgkin lymphomas using a specific treatment protocol. It may help doctors confirm how well the regimen works in young patients and improve care over time.
Moscow, RFAges 1 day–18 years - NCT05549167RecruitingPhase 3
Sirolimus for children with juvenile nasal blood tumors
This trial tests whether sirolimus can shrink or control juvenile nasopharyngeal angiofibroma in children and teens, and checks its safety. It may help families who cannot rely only on surgery, especially for larger or hard-to-treat tumors.
MoscowAges 7–18 - NCT07867522Recruiting
Preventing bile leaks after liver surgery in children
This study tests a way to prevent bile leaks after surgery to remove part of the liver in children. Bile is a digestive fluid made by the liver, and if it leaks after surgery it can cause problems. The approach involves a special technique during the operation to reduce the chance of this happening.
MoscowAges birth–18 years - NCT06805734Recruiting
Tracking health in children with PTEN gene changes
This study follows children and their affected relatives who have a harmful change in the PTEN gene. The goal is to understand the health risks, especially the chance of developing cancer, over time.
MilanAges Up to 17 years - NCT06939322Recruiting
Long-term monitoring app for childhood cancer survivors
This trial tests whether a special software (LOG-AFTER) helps people who had cancer before age 25 keep up with long-term screenings. It aims to make follow-up care easier and more consistent.
Angers, Maine Et LoireAges 15 years+ - NCT06982066Recruiting
Helping Young Cancer Patients Talk with Their Care Team
This study works with teens and young adults (ages 15–25) who have cancer and are currently in treatment. It tests a way to help you talk better with your doctors and nurses about your care, so they can understand your needs and preferences more clearly.
Hartford, ConnecticutAges 15–25 - NCT04477681Recruiting
Expanded access to cancer medicines for young people who need options
This trial helps children, teens, and young adults get an innovative cancer medicine when their disease has returned or hasn’t responded—and standard options are not available. It checks whether a “compassionate use” or off-label medicine plan can be carried out safely for the people who need it.
Villejuif, Val de MarneAges Up to 25 years - NCT07727694Recruiting
Access to new cancer drugs for children and young adults
This trial helps children, teens, and young adults with cancer get early access to promising new drugs that are not yet fully approved for their age group. It collects information on how these drugs work in real-world use.
AntwerpAges birth–25 years - NCT05711667RecruitingPhase 3
Letermovir to prevent CMV after stem cell transplant in kids
This trial tests whether the medicine letermovir can prevent a common virus (CMV) from coming back after an allogeneic stem cell transplant in children. It may help lower the risk of CMV infection during the vulnerable period right after transplant.
Birmingham, AlabamaAges 2–18 - NCT05564026Recruiting
Study of DNA patterns in childhood germ cell tumors
This study looks at “molecular” (DNA-related) features of germ cell tumors in children and teens. It also follows patients over time, which can help researchers understand tumor patterns and improve future care.
Minneapolis, MinnesotaAges Any age - NCT06054295Recruiting
Twin study of childhood brain tumors
This study looks at genetic differences between identical twins where only one twin has a childhood brain or spinal cord tumor. It helps researchers understand why some children get cancer and others don't.
Minneapolis, MinnesotaAges Up to 18 years - NCT05023785Recruiting
Lifestyle program for cancer survivors with early heart strain
This trial tests a structured lifestyle and exercise change program for young people who finished cancer treatment and have signs of early heart weakness. The goal is to improve heart health and lower the chance of heart failure later.
Toronto, OntarioAges 18–45 - NCT05275881Recruiting
Virtual reality during procedures for young blood or cancer patients
This trial tests whether using virtual reality (VR) during certain procedures can make them easier for children, teens, and young adults with blood or cancer-related conditions. Participants must be able to safely use a VR headset and be willing to take part.
PoitiersAges 7–24 - NCT02013336RecruitingPhase 1
Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors
Cincinnati, OhioAges 1–20 - NCT04726241RecruitingPhase 1/Phase 2
Testing blood and bone marrow samples in young leukemia patients
This trial looks at blood and bone marrow samples from children and teens whose leukemia has come back or is hard to treat. The goal is to better understand the disease and guide future options for these patients.
Birmingham, AlabamaAges Up to 22 years - NCT03067181RecruitingPhase 3
Active surveillance and chemotherapy for germ cell tumors
This study looks at how to manage germ cell tumors in children and young adults using careful monitoring for some patients and chemotherapy for others. It aims to see whether these approaches can control the cancer while avoiding unnecessary treatment when possible.
Birmingham, AlabamaAges Any age
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Common questions
- Are there clinical trials for pediatric oncology?
- Yes. Clin2 currently lists 66 recruiting pediatric oncology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric oncology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric oncology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.