Clinical trials
Pediatric Oncology clinical trials
Below are recruiting pediatric oncology clinical trials, each written for real people, not researchers. We’re tracking 68 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06071897RecruitingPhase 3
Chemo-immunotherapy for high-risk neuroblastoma
This trial tests a combination of chemotherapy and immunotherapy as a first treatment for children and young adults with high-risk neuroblastoma. The goal is to see if this approach can improve outcomes.
MoscowAges 1.5 years–18 years - NCT06198842RecruitingPhase 2
Low-dose treosulfan with PTCy for Nijmegen Breakage Syndrome transplant
This trial tests a low-dose chemotherapy regimen (treosulfan) combined with a drug called PTCy to prepare children with Nijmegen Breakage Syndrome for a stem cell transplant. The goal is to reduce side effects while helping the donor cells take hold safely.
MoscowAges 3 months–21 years - NCT06296732Recruiting
Keyhole surgery for childhood neuroblastoma
This study looks at using keyhole (laparoscopic) surgery to remove neuroblastoma tumors in children. It groups tumors by risk factors to see which children can safely have this less invasive surgery.
MoscowAges 1 day–18 years - NCT06756152RecruitingPhase 2/Phase 3
Preventing GVHD after transplant for blood cancers in children and young adults
This trial tests a combination of four medicines (cyclophosphamide, abatacept, vedolizumab, and ruxolitinib) to prevent graft-versus-host disease (GVHD) after a stem cell transplant for children and young adults with certain blood cancers. The goal is to see if this approach reduces the risk of GVHD, a serious complication where donor cells attack the body.
MoscowAges 1 day–21 years - NCT07232134RecruitingPhase 3
Treating AML in children with Down syndrome
This trial tests a treatment plan for children with Down syndrome who have been diagnosed with acute myeloid leukemia (AML) or a related bone marrow condition. The goal is to see how well the therapy works and to help guide doctors in choosing the best approach.
MoscowAges 1 day–18 years - NCT07256210RecruitingPhase 2
Donor NK cells to prevent leukemia return after stem cell transplant
This trial tests whether giving donor natural killer (NK) cells after a stem cell transplant can help prevent leukemia from coming back. It is for people aged 14-25 with certain hard-to-treat leukemias who are already getting a stem cell transplant from a related donor.
MoscowAges 1 month–25 years - NCT07323069Recruiting
Nurse-led sleep program for children with cancer
This trial tests a special nurse-led program to help children with cancer sleep better. It includes simple steps to improve sleep and is designed for kids who are between 6 and 12 years old and currently getting cancer treatment.
Kowloon BayAges 6–12 - NCT07366801RecruitingPhase 2/Phase 3
Preventing graft versus host disease in children with blood cancer
This trial tests if adding special immune cells (Treg cells) to a stem cell transplant from a half-matched donor can lower the risk of graft versus host disease (a serious side effect where donor cells attack the patient's body) in children and young adults with blood cancers.
MoscowAges 1–25 - NCT06805734Recruiting
Tracking health in children with PTEN gene changes
This study follows children and their affected relatives who have a harmful change in the PTEN gene. The goal is to understand the health risks, especially the chance of developing cancer, over time.
MilanAges Up to 17 years - NCT06939322Recruiting
Long-term monitoring app for childhood cancer survivors
This trial tests whether a special software (LOG-AFTER) helps people who had cancer before age 25 keep up with long-term screenings. It aims to make follow-up care easier and more consistent.
Angers, Maine Et LoireAges 15 years+ - NCT07727694Recruiting
Access to new cancer drugs for children and young adults
This trial helps children, teens, and young adults with cancer get early access to promising new drugs that are not yet fully approved for their age group. It collects information on how these drugs work in real-world use.
AntwerpAges birth–25 years - NCT04477681Recruiting
Expanded access to cancer medicines for young people who need options
This trial helps children, teens, and young adults get an innovative cancer medicine when their disease has returned or hasn’t responded—and standard options are not available. It checks whether a “compassionate use” or off-label medicine plan can be carried out safely for the people who need it.
Villejuif, Val de MarneAges Up to 25 years - NCT06982066Recruiting
Helping Young Cancer Patients Talk with Their Care Team
This study works with teens and young adults (ages 15–25) who have cancer and are currently in treatment. It tests a way to help you talk better with your doctors and nurses about your care, so they can understand your needs and preferences more clearly.
Hartford, ConnecticutAges 15–25 - NCT05711667RecruitingPhase 3
Letermovir to prevent CMV after stem cell transplant in kids
This trial tests whether the medicine letermovir can prevent a common virus (CMV) from coming back after an allogeneic stem cell transplant in children. It may help lower the risk of CMV infection during the vulnerable period right after transplant.
Birmingham, AlabamaAges 2–18 - NCT05564026Recruiting
Study of DNA patterns in childhood germ cell tumors
This study looks at “molecular” (DNA-related) features of germ cell tumors in children and teens. It also follows patients over time, which can help researchers understand tumor patterns and improve future care.
Minneapolis, MinnesotaAges Any age - NCT05023785Recruiting
Lifestyle program for cancer survivors with early heart strain
This trial tests a structured lifestyle and exercise change program for young people who finished cancer treatment and have signs of early heart weakness. The goal is to improve heart health and lower the chance of heart failure later.
Toronto, OntarioAges 18–45 - NCT06054295Recruiting
Twin study of childhood brain tumors
This study looks at genetic differences between identical twins where only one twin has a childhood brain or spinal cord tumor. It helps researchers understand why some children get cancer and others don't.
Minneapolis, MinnesotaAges Up to 18 years - NCT05275881Recruiting
Virtual reality during procedures for young blood or cancer patients
This trial tests whether using virtual reality (VR) during certain procedures can make them easier for children, teens, and young adults with blood or cancer-related conditions. Participants must be able to safely use a VR headset and be willing to take part.
PoitiersAges 7–24 - NCT04726241RecruitingPhase 1/Phase 2
Testing blood and bone marrow samples in young leukemia patients
This trial looks at blood and bone marrow samples from children and teens whose leukemia has come back or is hard to treat. The goal is to better understand the disease and guide future options for these patients.
Birmingham, AlabamaAges Up to 22 years - NCT03067181RecruitingPhase 3
Active surveillance and chemotherapy for germ cell tumors
This study looks at how to manage germ cell tumors in children and young adults using careful monitoring for some patients and chemotherapy for others. It aims to see whether these approaches can control the cancer while avoiding unnecessary treatment when possible.
Birmingham, AlabamaAges Any age
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Common questions
- Are there clinical trials for pediatric oncology?
- Yes. Clin2 currently lists 68 recruiting pediatric oncology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric oncology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric oncology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.