Preventing graft-versus-host disease after stem cell transplant for immune disorders
Treatments studied
Part of Genetic & congenital, Immune system & allergy clinical trials.
This trial tests a combination of two drugs, ruxolitinib and PTCy, to prevent graft-versus-host disease (a common complication) in children receiving a stem cell transplant for inborn errors of immunity. The goal is to make the transplant safer and more effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between birth and 20 years old.
- You must have an inborn error of immunity (a genetic condition affecting the immune system) that qualifies for a stem cell transplant.
- A parent or legal guardian must sign a consent form agreeing to your participation.
- You must not have a severe illness unrelated to your immune condition that would add extra risk from the transplant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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