Clinical trials
Periapical Periodontitis clinical trials
Below are recruiting periapical periodontitis clinical trials, each written for real people, not researchers. We’re tracking 14 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07019298Recruiting
Comparing dental filling methods for root canals
This trial studies different ways to fill a root canal after treatment to see which works best. It may help if you have a tooth with an infected or dying nerve.
Madrid, SpainAges 18 years+ - NCT05763420Enrolling by invitation
Testing a bioceramic root-canal sealer in adult molar teeth
This trial tests how well a bioceramic sealer works for primary (first-time) root canal treatment in permanent back teeth. It may help by improving the chances that the treated tooth heals and stays functional.
Janūb as Surrah, Hawalli GovernateAges 18–65 - NCT06587048Recruiting
New bone window surgery for root canal infections
This trial tests a new way to perform root-end surgery using a special ultrasound device. It aims to treat infections at the tip of a tooth root by making a small opening in the bone, which may help you heal faster.
Rohtak, HaryanaAges 18–60 - NCT06890676Recruiting
Dental care in nursing homes to prevent infections and improve health
This study tests whether bringing dental care to nursing home residents can reduce mouth infections, pneumonia, and help control blood sugar in people with diabetes. If you live in a nursing home and are 60 or older, you may be able to join.
Jefferson City, MissouriAges 60–100 - NCT05439330Recruiting
Dental MRI to help diagnose jaw, gum, and tooth problems
This study tests whether a special dental MRI can give useful pictures to diagnose jaw joint problems, tooth-related tissue changes, and gum/inflammation issues, and to help plan some dental implant treatments. If you need imaging for these reasons, the trial may help doctors choose the best next treatment by using clearer, dedicated scans.
AarhusAges 18 years+ - NCT07734987Recruiting
Root tip surgery accuracy with a 3D-printed guide
This trial tests whether using a custom 3D-printed guide helps make root-end surgery more accurate and improves healing. It may be right for you if you have an infected or damaged root tip that needs surgery.
Ho Chi Minh CityAges 16 years+ - NCT07018284Recruiting
Pain after root canal filling with different sealers
This study compares pain levels after root canal treatment using two different types of sealer material. It aims to find which sealer may cause less discomfort.
MadridAges 18 years+ - NCT07343804Recruiting
Dental root canal and heart disease risk study
This trial tests whether treating a tooth infection with a root canal can lower blood markers linked to heart risk in people with stable heart disease.
Rohtak, HaryanaAges 30 years+ - NCT07439614Recruiting
Comparing two ways to clean a dead nerve during a root canal
This trial compares two different ways to clean a molar tooth during a root canal when the nerve is dead. The goal is to find which method is better at removing infection without causing discomfort.
Buffalo, New YorkAges 18–70 - NCT07448571Recruiting
Testing i-PRF for better root canal retreatment healing
This study tests whether using a special platelet-rich concentrate (i-PRF) during a root canal retreatment can help heal infection at the tip of the root better than standard retreatment alone. It is for adults with a previously treated upper front tooth that now shows signs of infection on X-ray.
IstanbulAges 18–50 - NCT07501585Recruiting
Hyaluronic acid gel for infected back tooth surgery
This trial tests whether putting hyaluronic acid (a natural gel-like substance) into the bone during root-end surgery helps heal infections in first molars (back teeth) that didn't get better after a root canal. It may be a good option if you have a small, stubborn infection and your gums are healthy.
MoscowAges 18 years+ - NCT07671326Recruiting
Bioceramic vs calcium hydroxide for infected molars
This study compares two types of medication placed inside a root canal to fight infection. It may be an option if you have an infected lower molar and are in generally good health.
Istanbul, IstanbulAges 18–65 - NCT07237620Recruiting
Comparing medicines for failed root canal treatment
This trial compares different medicines placed inside the tooth after a failed root canal to help heal the infection at the root tip. If you have a back tooth that still has an infection even though it had a root canal years ago, this study may test which medicine works best for you.
Hatay, AntakyaAges 18–60 - NCT06545084Recruiting
Better healing after root-end surgery using a special blood clot
This study tests whether adding a concentrated blood clot (L-PRF) to standard root-end surgery helps tooth-related infections heal faster and better. You may be a good fit if you have a persistent infection at the tip of a tooth root and need this type of surgery.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for periapical periodontitis?
- Yes. Clin2 currently lists 14 recruiting periapical periodontitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a periapical periodontitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a periapical periodontitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.