Clinical trials
Phenotype clinical trials
Below are recruiting phenotype clinical trials, each written for real people, not researchers. We’re tracking 312 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03716908Recruiting
Study of hearing gene changes in DFNA9 family members
This study looks at how a specific inherited gene change (the P51S COCH mutation) connects to hearing and balance symptoms over time. It may help researchers better predict who will develop symptoms and how they may progress.
AntwerpAges 18 years+ - NCT03428009Recruiting
Study links dystonia symptoms to genetic and brain differences
This study looks at how different types of dystonia (movement disorders) relate to genetics and brain findings from scans. You might help researchers understand why symptoms look different from person to person and what patterns may matter.
Dallas, TexasAges 11 years+ - NCT07082244Recruiting
Gum and bone shaping for dental implants
This study tests a procedure to improve the shape of the gum and bone around a dental implant in people with thin gums. It uses a special graft material to make the area thicker and more stable for a better-looking result.
Ann Arbor, MichiganAges 18 years+ - NCT03231241Recruiting
Study of worsening headaches using scans and blood testing
This study looks at why headaches can become long-lasting (“chronified”) by combining answers from online questionnaires, brain imaging, and blood protein tests. Your participation may help researchers find biological clues that could improve how headache problems are understood and treated.
Stanford, CaliforniaAges 18 years+ - NCT02886611Recruiting
Study for genetic eye surface stem cell problems
This trial studies people whose eye surface problems are caused by an inherited (genetic) condition. It aims to better understand how specific genetic changes relate to symptoms, which may guide more personalized care.
ParisAges Any age - NCT03016819RecruitingPhase 3
Test drugs anlotinib and catequentinib for advanced sarcoma
This Phase 3 study tests two anti-cancer medicines (anlotinib and catequentinib) for people with certain advanced soft-tissue sarcomas, including alveolar soft part sarcoma, synovial sarcoma, and leiomyosarcoma. It is designed for tumors that cannot be removed and that have either grown despite treatment or no longer respond to standard options.
Phoenix, ArizonaAges 18 years+ - NCT02692885Recruiting
Study body fat tissue to learn how it affects metabolism
This study looks at samples of body fat to understand what controls metabolism (how your body uses energy). You may be asked for a fat tissue sample during surgery or through a special biopsy scan, depending on your situation.
Bethesda, MarylandAges 18–90 - NCT02362685Recruiting
Metabolic exercise testing study
This study is about doing a breathing-and-heart performance test while you exercise to better understand how your body uses energy. You may join if you’re referred for this type of test and can safely complete it.
BrestAges 5 years+ - NCT02614911Recruiting
Genetics and health profile study for early severe bowel disease
This study looks at how an early-onset bowel illness looks and what genetic changes may be involved. It may help researchers better understand inherited causes and improve future care for families affected by these conditions.
BordeauxAges Any age - NCT02447861Recruiting
Study of behavior differences in 3q29 deletion or duplication
This study looks at how brain development and behavior may differ in people with a 3q29 deletion or 3q29 duplication. It may help researchers understand what to expect and how these conditions affect daily life.
Piscataway, New JerseyAges Any age - NCT02602769Recruiting
Testing blood traits in children with ROHHAD syndrome
This trial studies children with ROHHAD syndrome to better understand their body chemistry and other blood features. The results may help researchers learn what drives the condition and how it might be tracked over time.
Boston, New YorkAges 2–20 - NCT01517425Enrolling by invitation
Using blood stem cells to study heart disease traits
This study uses your blood to create special lab cells (induced pluripotent stem cells) to better understand heart-related differences between people with coronary artery disease and generally healthy older adults. It may help researchers learn what biological traits are linked to heart risk and how those traits work.
La Jolla, CaliforniaAges 18 years+ - NCT06108089Recruiting
Hypoxia imaging for head and neck cancer treatment planning
This study uses a special MRI scan to measure oxygen levels in your head and neck tumor. The goal is to learn if this scan can help doctors choose the best treatment plan for you.
Salt Lake City, UtahAges 18 years+ - NCT06325800Recruiting
Heart and blood vessel health registry
This study collects information from people at risk for heart disease, stroke, or kidney problems to better understand how to prevent these conditions. If you join, you'll be helping doctors learn more about how to keep blood vessels healthy.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT01257269Recruiting
Study of genetic and blood features in Upshaw-Schulman
This study looks at how genetic changes (ADAMTS13 gene mutations) and blood test results relate to symptoms and treatment needs in Upshaw-Schulman syndrome. It may help doctors better predict disease behavior and personalize care.
Oklahoma City, OklahomaAges Any age - NCT01016613Enrolling by invitation
Kidney health study that helps build a tissue and data bank
This study collects health information and biological samples to better understand kidney disease and support future kidney research. It may help your care indirectly by improving how kidney conditions are recognized and studied.
Ann Arbor, MichiganAges Any age - NCT00768820RecruitingPhase 4
Study brain and mental health in people with 22q11 deletion
This trial looks at how thinking and mental health (psychiatric symptoms) show up in people who have a specific chromosome deletion. It may help researchers understand patterns in this condition and improve future care.
Petah TikvaAges Any age - NCT06533579RecruitingPhase 1/Phase 2
Gene therapy for CD19-positive blood cancers
This trial tests a new gene therapy treatment for people with certain types of leukemia or lymphoma that have the CD19 marker and have not responded to other treatments. The therapy uses a virus to deliver a gene to target and kill cancer cells.
Duarte, CaliforniaAges 13–90 - NCT01145196Recruiting
Study drug eye damage and genes in Plaquenil users
This study looks at how Plaquenil (hydroxychloroquine) can harm the retina (the eye’s light-sensing layer) and whether genetics affect who gets affected. You may help by sharing medical details and providing an eye-related blood sample so researchers can compare gene patterns to eye findings.
Bethesda, MarylandAges 18–120 - NCT00271622Recruiting
Screening test for child or adult brain and behavior patterns
This study uses a structured check-up to learn about how someone’s thinking, behavior, and development may differ from typical patterns. It involves an interview and possibly medical, nervous-system, and blood or urine tests to understand what kinds of issues might be present.
Bethesda, MarylandAges 1 month+ - NCT01132885Recruiting
Brain scans in children with Williams syndrome
This study uses brain testing—often MRI scans—to learn how the brains of children with Williams syndrome are different from typical development. It may help researchers better describe brain patterns and improve future care for people with Williams syndrome.
Bethesda, MarylandAges 5–99 - NCT06361641Recruiting
Study of immune cells in blood cancers
This study looks at immune cells (monocytes) in people with certain blood cancers. Researchers want to understand how these cells behave and change over time. You can join if you are newly diagnosed and haven't started treatment yet.
Angers, Maine et LoireAges 18 years+ - NCT07762573Recruiting
Predicting COPD progression with dynamic chest x-rays
This study looks at whether a special type of chest x-ray (called dynamic chest radiography) can help predict how chronic obstructive pulmonary disease (COPD) might progress. It may help doctors better understand the disease and plan treatment.
Guangzhou, GuangdongAges 30–85 - NCT07764588Recruiting
Immune cell study after a heart attack
This study looks at how immune cells change in the first few hours after a severe heart attack (STEMI) and how that relates to early scar healing. It may help doctors understand why some patients heal better than others.
ShanghaiAges 18–80
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Common questions
- Are there clinical trials for phenotype?
- Yes. Clin2 currently lists 312 recruiting phenotype studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a phenotype trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a phenotype trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.