Study of revumenib and mezigdomide for leukemia
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests two experimental drugs, revumenib and mezigdomide, for people with acute leukemia that has certain genetic changes (NPM1, KMT2A, or NUP98) and has come back or not responded to prior treatment. The goal is to see if this combination can help control the leukemia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 12 years old or older and weigh at least 40 kg (about 88 lbs).
- Your leukemia has a specific genetic change (NPM1 mutation, or KMT2A or NUP98 rearrangement).
- You have already tried at least one treatment for your leukemia, and it didn't work or it came back.
- You have not taken mezigdomide before.
- Your blood counts, heart, liver, and kidney function are within a safe range for this study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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